ChemicalBook >> CAS DataBase List >>ILIMAQUINONE

ILIMAQUINONE

ILIMAQUINONE structure

CAS No.: 71678-03-0

Chemical Name:: ILIMAQUINONE

Synonyms: IQ;ILIMAQUINONE;illimaquinone;(-)-Ilimaquinine;(-)-ILIMAQUINONE;5-Epiilimaquinone;Ilimaquinone - CAS 71678-03-0 - Calbiochem;3-[(decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone;3-[(DECAHYDRO-1B,2B,4AB-TRIMETHYL-5-METHYLENE-1-NAPHTHYL)METHYL]-2-HYDROXY-5-METHOXYBENZOQUINONE;2-[[(1R,8aα)-1,2β,4aβ-Trimethyl-5-methylenedecalin-1α-yl]methyl]-3-hydroxy-6-methoxy-1,4-benzoquinone

CBNumber:: CB5267651

Molecular Formula:: C22H30O4

Molecular Weight:: 358.47

MDL Number:: MFCD22200891

MOL File:: 71678-03-0.mol

Last updated:2023-05-18 11:31:19

Request For Quotation

ILIMAQUINONE Properties

Melting point	108-110℃ (pentane )
alpha	D23 -23.2° (c = 1.12 in CHCl3)
Boiling point	478.4±45.0 °C(Predicted)
Density	1.14±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO: Soluble; Ethanol: Soluble; Hexane: Soluble; Methanol: Soluble
pka	2.92±0.50(Predicted)
form	Red solid
FDA UNII	5U0WAN3N8Q
Proposition 65 List	IQ (2-Amino-3-methylimidazo-[4-5-f]quinoline)

SAFETY

Risk and Safety Statements

WGK Germany	3

ILIMAQUINONE price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Alfa Aesar	J67278	Ilimaquinone, 98%	71678-03-0	100microg	$199	2021-12-16	Buy
Cayman Chemical	15124	Ilimaquinone ≥98%	71678-03-0	100μg	$209	2024-03-01	Buy
Usbiological	044951	Ilimaquinone	71678-03-0	100ug	$350	2021-12-16	Buy
TRC	I267318	Ilimaquinone	71678-03-0	500μg	$920	2021-12-16	Buy
Adipogen Life Sciences	AG-CN2-0038-C100	Ilimaquinone ≥98%(HPLC)	71678-03-0	100μg	$130	2021-12-16	Buy

Product number	Packaging	Price	Buy
J67278	100microg	$199	Buy
15124	100μg	$209	Buy
044951	100ug	$350	Buy
I267318	500μg	$920	Buy
AG-CN2-0038-C100	100μg	$130	Buy

ILIMAQUINONE Chemical Properties,Uses,Production

Description

Ilimaquinone is a natural sesquiterpene quinone that has antimicrobial, anti-HIV, anti-mitotic, and anti-inflammatory properties. In mammalian cells, 25 μM ilimaquinone reversibly induces vesiculation of Golgi membranes, blocking the secretory pathway. It inhibits the conversion of S-adenosylhomocysteine (SAH) to homocysteine by SAH hydrolase (IC₅₀ = 40 μM). Ilimaquinone also inhibits DNA polymerase β and dual specificity phosphatase Cdc25B (IC₅₀ = 45.2 and 92 μM, respectively) and, at 10 μM, activates gene expression through hypoxia-inducible factor-1.

Uses

Biological probe for intracellular communications and vesicle-mediated transport.

Uses

Ilimaquinone is an ADP-ribosylation factor (ARF) and β-COP to the Golgi membrane inhibitor.

Definition

ChEBI: A natural product found in Dactylospongia elegans.

General Description

A cell-permeable marine sponge metabolite with anti-microbial, anti-HIV, anti-inflammatory, and anti-mitotic properties. Induces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules. Inhibits cellular methylations through its interaction with S-adenosylhomocysteinase. Blocks the cytotoxicity of ricin and diphtheria toxin. Acts as an inhibitor of the RNase H activity of HIV-1.

Biochem/physiol Actions

Primary TargetInduces a complete and reversible breakdown of Golgi membranes into smaller vesicular structures and causes depolymerization of microtubules.

ILIMAQUINONE Preparation Products And Raw materials

Raw materials

Preparation Products

ILIMAQUINONE Suppliers

Global( 58)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Tauto Biotech Co., Ltd.	021-51320588	tauto@tautobiotech.com	China	3989	66
Hotechem Shanghai Co., Ltd.,	021-34621078 13120882795	465106944@qq.com	China	858	56
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58

Supplier	Advantage
Aladdin Scientific	58
Shanghai Tauto Biotech Co., Ltd.	66
Hotechem Shanghai Co., Ltd.,	56
Shanghai EFE Biological Technology Co., Ltd.	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58

71678-03-0(ILIMAQUINONE)Related Search:

5'-GUANYLYLIMIDODIPHOSPHATE TRISODIUM EMBELIN 2,5-DIHYDROXY-1,4-BENZOQUINONE PRIMIN ILIMAQUINONE

3-methoxy-2,5-toluquinone METHOXYBENZOQUINONE p-Toluquinone

1of2

3-[(DECAHYDRO-1B,2B,4AB-TRIMETHYL-5-METHYLENE-1-NAPHTHYL)METHYL]-2-HYDROXY-5-METHOXYBENZOQUINONE 3-[(DECAHYDRO-1BETA,2BETA,4A-BETA-TRIMETHYL-5-METHYLENE-1-NAPHTHYL)-METHYL]-2-HYDROXY-5-METHOXYBENZOQUINONE 3-[(DECAHYDRO-1BETA,2BETA,4A-BETA-TRIMETHYL-5-METHYLENE-1-NAPTHYL)METHYL]-2-HYDROXY-5-METHOXYBENZOQUINONE 3-[(DECAHYDRO-1BETA,2BETA,4ALPHA-BETA-TRIMETHYL-5-METHYLENE-1-NAPHTHYL)METHYL]-2-HYDROXY-5-METHOXYBENZOQUINONE IQ ILIMAQUINONE 3-[(decahydro-1β,2β,4aβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone illimaquinone 5-Epiilimaquinone (-)-Ilimaquinine 2-[[(1R,8aα)-1,2β,4aβ-Trimethyl-5-methylenedecalin-1α-yl]methyl]-3-hydroxy-6-methoxy-1,4-benzoquinone 3-[[(1R,8aα)-Decahydro-1,2β,4aβ-trimethyl-5-methylenenaphthalene-1α-yl]methyl]-2-hydroxy-5-methoxy-2,5-cyclohexadiene-1,4-dione 3-[[[(1R,8aα)-Decahydro-1,2β,4aβ-trimethyl-5-methylenenaphthalen]-1α-yl]methyl]-2-hydroxy-5-methoxy-2,5-cyclohexadiene-1,4-dione 3-[[(1R,2S,4aS,8aS)-Decahydro-1,2,4a-trimethyl-5-methylene-1-naphthalenyl]methyl]-2-hydroxy-5-methoxy-2,5-cyclohexadiene-1,4-dione (-)-ILIMAQUINONE Ilimaquinone - CAS 71678-03-0 - Calbiochem 2,5-CYCLOHEXADIENE-1,4-DIONE,3-[[(1R,2S,4AS,8AS)-DECAHYDRO-1,2,4A-TRIMETHYL-5-METHYLENE-1-NAPHTHALENYL] METHYL]-2-HYDROXY-5-METHOXY- 71678-03-0 Cell Biology Cell Signaling and Neuroscience BioChemical Organelle Proteins and Related Molecules Cytoskeleton and Extracellular Matrix