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Glycine ethyl ester hydrochloride

Glycine ethyl ester hydrochloride structure

CAS No.: 623-33-6

Chemical Name:: Glycine ethyl ester hydrochloride

Synonyms: ETHYL GLYCINATE HYDROCHLORIDE;GLYCINE ETHYL ESTER;GLYCINE ETHYL ESTER HCL;GEE;H-GLY-OET HCL;ETHYL AMINOACETATE HYDROCHLORIDE;usafdo-10;Gly-OEt HCl;ycine EthyL;GLYCINE-OET HCL

CBNumber:: CB5275670

Molecular Formula:: C4H9NO2.ClH

Molecular Weight:: 139.58

MDL Number:: MFCD00012871

MOL File:: 623-33-6.mol

MSDS File:: SDS

Last updated:2024-03-27 13:09:27

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Glycine ethyl ester hydrochloride Properties

Melting point	145-146 °C(lit.)
Density	1.371 g/cm3
storage temp.	2-8°C
solubility	>1000 g/L (20 °C)
pka	pK1:7.66(＋1) (25°C)
form	Crystalline Powder
color	White
PH	2.9 (10g/l, H2O, 20℃)
Odor	Odorless
Water Solubility	>1000 g/L (20 ºC)
Sensitive	Hygroscopic
BRN	3594034
InChIKey	TXTWXQXDMWILOF-UHFFFAOYSA-N
CAS DataBase Reference	623-33-6(CAS DataBase Reference)
EPA Substance Registry System	Glycine, ethyl ester, hydrochloride (623-33-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H318

Precautionary statements

P280-P305+P351+P338

Hazard Codes

Risk Statements

41-36/37/38

Safety Statements

26-39-24/25-37/39

WGK Germany

RTECS

MC0525000

TSCA

Yes

HS Code

29224995

NFPA 704

	0
0		0

Glycine ethyl ester hydrochloride price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	G6503	Glycine ethyl ester hydrochloride 99%	623-33-6	5G	$35.4	2024-03-01	Buy
Sigma-Aldrich	G6503	Glycine ethyl ester hydrochloride 99%	623-33-6	100g	$65.6	2024-03-01	Buy
Sigma-Aldrich	G6503	Glycine ethyl ester hydrochloride 99%	623-33-6	500g	$97.7	2024-03-01	Buy
TCI Chemical	G0102	Glycine Ethyl Ester Hydrochloride >99.0%(T)	623-33-6	25g	$19	2024-03-01	Buy
TCI Chemical	G0102	Glycine Ethyl Ester Hydrochloride >99.0%(T)	623-33-6	500g	$75	2024-03-01	Buy

Product number	Packaging	Price	Buy
G6503	5G	$35.4	Buy
G6503	100g	$65.6	Buy
G6503	500g	$97.7	Buy
G0102	25g	$19	Buy
G0102	500g	$75	Buy

Glycine ethyl ester hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Crystalline

Uses

Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.

Uses

As a Glycine (G615990) ester, Glycine ethyl ester hydrochloride can be used as parakeratosis inhibitor and external composition for skin.

Synthesis

A production method for glycine ethyl ester hydrochloride:First add dehydrated ethanol in 1# reactor, pass into anhydrous hydrogen chloride to obtain hydrochloric acid-ethanol solution; Add a certain amount of triethyl orthoformate and glycine and hydrochloric acid-ethanol solution in 2# reactor, in the Reaction under action; after the reaction is complete, distill and recover ethanol and ethyl formate; then add alcohol-ether mixture, wash, filter, concentrate, recrystallize, and vacuum dry to obtain ethyl glycine hydrochloride.

Purification Methods

Crystallise it from absolute EtOH or EtOH/Et2O. [Marvel Org Synth Coll Vol II 310 1943, Beilstein 4 II 780, 4 III 3 75.]

Glycine ethyl ester hydrochloride synthesis

Synthesis of Glycine ethyl ester hydrochloride from Ethanol and Glycine

Glycine ethyl ester hydrochloride Preparation Products And Raw materials

Raw materials

Hydrogen chloride ethanol solution Ethanol Hydrochloric acid alcohol Glycine weak

Hydrochloric acid Hydrogen Hexamethylenetetramine

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Preparation Products

1-(Boc-amino)cyclopropanecarboxylic acid N-Boc-3-cyano-4-hydroxypyrrolidine ethyl 2-(3-bromo-2-oxopyrazin-1(2H)-yl)acetate ETHYL 2-[(2-THIENYLCARBONYL)AMINO]ACETATE 2,2-Dimethyl-3-(2-methylpropyl)cyclopropanecarboxylic acid p-(methoxymethyl)benzyl ester

tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate Ethyl N-(diphenylmethylene)glycinate Ethyl imidazole-4-carboxylate ethyl 2-(3,4-dihydro-2,3-dioxopyrazin-1(2H)-yl)acetate N-(ETHOXYCARBONYL)-N-(ETHOXYCARBONYKLETHYL)GLYCINE ETHYL ESTER

H-GLY-AMC HBR 1-Aminocyclopropanecarboxylic acid Glycine methyl ester hydrochloride N-FORMYLGLYCINE ETHYL ESTER 3-BROMO-6-METHYL-2-OXO-1(2H)-PYRAZINEACETIC ACID ETHYL ESTER

Anagrelide ethyl 2-(3,4-dihydro-6-methyl-2,3-dioxopyrazin-1(2H)-yl)acetate Ethyl diazoacetate 4-Imidazolemethanol hydrochloride Tetramethrin

4-BOC-AMINOMETHYL-1-N-BOC-PYRROLIDIN-3-OL 4,5,6,7-TETRAHYDRO-2-METHYLFURO[2,3-C]PYRIDINE

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Glycine ethyl ester hydrochloride Suppliers

Global( 737)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
DONBOO AMINO ACID COMPANY	+8613063595538	donboo@donboo.com	China	9365	58
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
Shandong Believe Chemical PTE.LTD	+86-18553607090 +8618553607090	1093908296@qq.com	China	1684	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
Sichuan HongRi Pharma-Tech Co.,Ltd	+86-028-64841719 +8618980456393	daisy@enlaibio.com	China	1369	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	885	50
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55

Supplier	Advantage
DONBOO AMINO ACID COMPANY	58
Shanghai Time Chemicals CO., Ltd.	55
Shandong Believe Chemical PTE.LTD	58
Hebei Mojin Biotechnology Co., Ltd	58
Anhui Ruihan Technology Co., Ltd	58
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from Glycine ethyl ester hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-26	H-Gly-Oet.HCl 623-33-6	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2023-10-30	Glycine ethyl ester hydrochloride 623-33-6	US $10.00 / kg	1kg	99%	20tons	Shandong Believe Chemical PTE.LTD
2023-09-08	Glycine ethyl ester hydrochloride 623-33-6	US $30.00 / kg	1kg	99%	20 tons	Anhui Ruihan Technology Co., Ltd

H-Gly-Oet.HCl
623-33-6
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Glycine ethyl ester hydrochloride
623-33-6
US $10.00 / kg
99%
Shandong Believe Chemical PTE.LTD

Glycine ethyl ester hydrochloride
623-33-6
US $30.00 / kg
99%
Anhui Ruihan Technology Co., Ltd

Glycine ethyl ester hydrochloride Spectrum

Glycine ethyl ester hydrochloride(623-33-6)MS Glycine ethyl ester hydrochloride(623-33-6)¹HNMR Glycine ethyl ester hydrochloride(623-33-6)¹³CNMR Glycine ethyl ester hydrochloride(623-33-6)IR1 Glycine ethyl ester hydrochloride(623-33-6)IR2 Glycine ethyl ester hydrochloride(623-33-6)Raman

623-33-6(Glycine ethyl ester hydrochloride)Related Search:

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Glycineethylesterhydrochlor Glycocollethylesterhydrochloride usafdo-10 glycine ethyhydnchlordeester Glycineethylester·HCl,Glycineethylesterhydrochloride Ethyl 2-aminoacetate, hydrochloride Glycine ethyl ester hydrochloride ,98% 2-Aminoacetic acid ethyl·hydrochloride Aminoacetic acid ethyl·hydrochloric acid Glycine ethyl·hydrochloride (2-Ethoxy-2-oxoethyl)aMMoniuM Chloride Glycine Ethyl Ester Monohydrochloride Glycine Hydrochloride Ethyl Ester ETHYL GLYCINATE HYDROCHLORIDE FOR SYNTHE Glycine ethyl ester HC1 Glycine ethyl ester hydrochloride, 99% 100GR Glycine ethyl ester hydrochloride, 99% 500GR Glycine ethylester HCI RARECHEM AL BW 0032 GLYCINE ETHYL ESTER HYDROCHLORIDE GLYCINE-OET HCL ETHYL AMINOACETATE HCL AMINO-ACETIC ACID ETHYL ESTER AMINOACETIC ACID ETHYL ESTER HYDROCHLORIDE Ethyl glycinate hydrochloride~H-Gly-OEt.HCl Ethyl Glycinate, HCl (1.00893) Glycine ethyl ester hydrochloride 99% Gly-OEt HCl Glycineethylesterhydrochloride,99% GlyClne ethyl ester HCl Ethyl glycinate hydrochloride for synthesis ycine EthyL Glycine ethyl ether hydrochloride GLYCINE ETHYL ESTER .HCl (623-33-6) GlycineEthylEsterHydrochloride> Ethylglycinathydrochlorid Glycine Impurity 10 glycine ethyl ester hydrochloric acid Ethyl glycine hydrochloride Glycine ethyl ester hydrochloride USP/EP/BP Glycine ethyl ester hydrochloride25 GLYCINE ETHYL ESTER HYDROCHLORIDE For Synthesis H-GLY-OET HCL GLYCINE ETHYL ESTER GLYCINE ETHYL ESTER HCL ETHYL AMINOACETATE HYDROCHLORIDE ETHYL GLYCINATE HYDROCHLORIDE GEE Glycine hexanoate hydrochloride Ethyl glycerate hydrochloride Glycine Ethyl Ester Hydrochloride (Ethyl Glycinate Hydrochloride) 623-33-6 C4H9NO2HClC4H10ClNO2 C4H9NO2xHCl CH3CH2O2CCH2NH2HCl NH2CH2COOC2H5HCl Amino Acids (C-Protected) Amino Acid Ethyl Esters