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2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE

2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE structure

CAS No.: 341-88-8

Chemical Name:: 2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE

Synonyms: hqno;kf8940;C04284;Pyo II;Antibiotic KF-8940;2-heptyl-4-quinolino1-oxide;NZPACTGCRWDXCJ-UHFFFAOYSA-N;2-Heptylquinolin-4-ol 1-oxide;2-Heptyl-4-quinolinol 1-oxide;4-Quinolinol, 2-heptyl-, 1-oxide

CBNumber:: CB5503571

Molecular Formula:: C16H21NO2

Molecular Weight:: 259.34

MDL Number:: MFCD00057295

MOL File:: 341-88-8.mol

MSDS File:: SDS

Last updated:2023-06-08 09:01:56

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2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Properties

Melting point	156-157°
Boiling point	445.8±37.0 °C(Predicted)
Density	1.09±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	Soluble in DMSO (up to 8 mg/ml with warming), or in Ethanol (up to 13 mg/ml with warming).
pka	1.07±0.40(Predicted)
form	White to off-white crystalline solid.
color	White
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
FDA UNII	1FU5S5CG6A

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H312-H315-H319

Precautionary statements

P280-P305+P351+P338

RTECS

VC5890000

Toxicity

LD50 intraperitoneal in mouse: 40mg/kg

NFPA 704

	0
2		0

2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	15159	HQNO ≥98%	341-88-8	5mg	$68	2024-03-01	Buy
Cayman Chemical	15159	HQNO ≥98%	341-88-8	10mg	$116	2024-03-01	Buy
Cayman Chemical	15159	HQNO ≥98%	341-88-8	50mg	$435	2024-03-01	Buy
American Custom Chemicals Corporation	INB0001935	2-HEPTYL-4-HYDROXYQUINOLINE-1-OXIDE 95.00%	341-88-8	5MG	$499.44	2021-12-16	Buy
ChemScene	CS-0104638	HQNO 98.04%	341-88-8	50mg	$320	2021-12-16	Buy

Product number	Packaging	Price	Buy
15159	5mg	$68	Buy
15159	10mg	$116	Buy
15159	50mg	$435	Buy
INB0001935	5MG	$499.44	Buy
CS-0104638	50mg	$320	Buy

2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Chemical Properties,Uses,Production

Description

HQNO (341-88-8) is a naturally occurring antagonist of dihydrostreptomycin. Potent inhibitor of the respiratory chain binding to the mitochondrial cytochrome b protein. HQNO inhibits NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR).

Uses

HQNO is a streptomycin antagonist. A naturally occurring antagonist of dihydrostreptomycin.

Definition

ChEBI: 2-heptyl-4-hydroxyquinoline N-oxide is an inhibitor of the mitochondrial respiratory chain at cytochrome bc1 and of photosynthetic electron flow immediately before cytochrome b559. It is a monohydroxyquinoline and a quinoline N-oxide.

References

References/Citations 1) Nakayama?et al. (1999),?Inhibitor studies of a new antibiotic, korormicin, 2-n-heptyl-4-hydroxyquinoline N-oxide and Ag+?toward the Na+-translocating NADH-quinone reductase from the marine Vibrio alginolyticus; Biol. Pharm. Bull.,?221064

2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Suppliers

Global( 64)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4121	55

Supplier	Advantage
Career Henan Chemica Co	58
BOC Sciences	58
Alfa Chemistry	58
InvivoChem	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
Shanghai Lollane Biological Technology Co.,Ltd.	55

2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE Spectrum

2-HEPTYL-4-HYDROXYQUINOLINE N-OXIDE(341-88-8)¹HNMR

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