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Indobufen

CAS No.
63610-08-2
Chemical Name:
Indobufen
Synonyms
2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid;d-INB;K 2930;K-3920;Ibustrin;INDOBUFEN;INDOBNFEN;lndobufen;d-Indobufen;Indobuprofen
CBNumber:
CB6213695
Molecular Formula:
C18H17NO3
Molecular Weight:
295.34
MDL Number:
MFCD00572250
MOL File:
63610-08-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 19:39:08
Product description Number Pack Size Price
Indobufen min. 98.0 % I1178 1G $81
Indobufen C6492 25mg $56
Indobufen I576500 25mg $70
Indobufen J54144 25mg $62
INDOBUFEN 95.00% API0004904 1G $1871.1
More product size

Indobufen Properties

Melting point 182-184°
Boiling point 518.1±50.0 °C(Predicted)
Density 1.275±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 4.39±0.10(Predicted)
color White
InChI InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)
InChIKey AYDXAULLCROVIT-UHFFFAOYSA-N
SMILES O=C1C2C=CC=CC=2CN1C1C=CC(C(CC)C(=O)O)=CC=1
CAS DataBase Reference 63610-08-2(CAS DataBase Reference)
FDA UNII 6T9949G4LZ
ATC code B01AC10
EPA Substance Registry System Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-.alpha.-ethyl- (63610-08-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

Indobufen price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical I1178 Indobufen min. 98.0 % 63610-08-2 1G $81 2026-04-30 Buy
ApexBio Technology C6492 Indobufen 63610-08-2 25mg $56 2026-05-06 Buy
TRC I576500 Indobufen 63610-08-2 25mg $70 2021-12-16 Buy
AK Scientific J54144 Indobufen 63610-08-2 25mg $62 2021-12-16 Buy
American Custom Chemicals Corporation API0004904 INDOBUFEN 95.00% 63610-08-2 1G $1871.1 2021-12-16 Buy
Product number Packaging Price Buy
I1178 1G $81 Buy
C6492 25mg $56 Buy
I576500 25mg $70 Buy
J54144 25mg $62 Buy
API0004904 1G $1871.1 Buy

Indobufen Chemical Properties,Uses,Production

Description

Indobufen is a platelet aggregation inhibitor related to the antiinflammatory agent indoprofen. It has shown clinical efficacy in peripheral artery disease, in prevention of deep vein thrombosis after myocardial infarction, and in blocking excercise-induced increase in platelet aggregation in angina patients.

Chemical Properties

Crystallized from methanol, melting point 182-184°C.

Originator

Erbamont (Italy)

Uses

Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombotic.

Definition

ChEBI: Indobufen is a member of isoindoles.

brand name

IBUSTRIN

Clinical Use

A reversible but very potent inhibitor of platelet COX-1 activity, was shown to have comparable clinical efficacy to that of aspirin in prevention of DVT after myocardial infarction and in blocking exercise-induced increase in platelet aggregation. In the secondary prevention of thromboembolic events, 100 or 200 mg of indobufen twice daily is as effective as warfarin or aspirin in patients with or without atrial fibrillation. Currently, indobufen is only available for routine clinical use in Europe.

36691-02-8
63610-08-2
Synthesis of Indobufen from Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-, ethyl ester

Indobufen Preparation Products And Raw materials

Global( 261)Suppliers
Supplier Tel Email Country ProdList Advantage
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
+86-029-86185165 +8618629664246 guoyuan@eastchinapharm.com China 1615 58
Beijing Hope Pharmaceutical Co., Ltd.
+86-010-67886402 +8613611125266 market@hopelife.cn China 72 58
Changzhou Rokechem Technology Co., Ltd.
18758118018 sales001@rokechem.com China 255 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 deasea125996@gmail.com China 2472 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8615965530500 nickzhang@hangyubiotech.com China 9922 58
airuikechemical co., ltd.
+86-18353166132 sales02@airuikechemical.com China 983 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29640 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6367 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460 faith@widelychemical.com CHINA 742 58

Related articles

View Lastest Price from Indobufen manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Indobufen pictures 2026-05-18 Indobufen
63610-08-2
US $0.00-0.00 / Kg/Drum 1KG 99%minHPLC 1000KG WUHAN FORTUNA CHEMICAL CO., LTD
Indobufen pictures 2026-05-18 Indobufen
63610-08-2
US $0.00-0.00 / kg 1kg 99% up by HPLC 20tons Sinoway Industrial co., ltd.
Indobufen pictures 2026-05-11 Indobufen
63610-08-2
US $64.00 / mg 99.63% 10g TargetMol Chemicals Inc.
  • Indobufen pictures
  • Indobufen
    63610-08-2
  • US $0.00-0.00 / Kg/Drum
  • 99%minHPLC
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Indobufen pictures
  • Indobufen
    63610-08-2
  • US $0.00-0.00 / kg
  • 99% up by HPLC
  • Sinoway Industrial co., ltd.
  • Indobufen pictures
  • Indobufen
    63610-08-2
  • US $64.00 / mg
  • 99.63%
  • TargetMol Chemicals Inc.

Indobufen Spectrum

1-Oxo-2-[p-[(α-ethyl)carboxyMethyl]phenyl]isoindoline 2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric Acid K 2930 (+-)-butyricaci 1-oxo-2-(p-((alpha-ethyl)carboxymethyl)phenyl)isoindoline 4-(1,3-dihydro-1-oxo-2h-isoindol-2-yl)-alpha-ethyl-benzeneaceticacid 2-[4-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PHENYL]-BUTYRIC ACID lndobufen INDOBNFEN INDOBUFEN 2-[4-(1-oxo-2-isoindolinyl)phenyl]butyric acid (2R)-2-[4-(3-Oxo-1H-isoindol-2-yl)phenyl]butanoic acid 1-Oxo-2-(p-((a-ethyl)carboxymethyl)phenyl)isoindoline 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)a-ethyl-benzeneacetic acid Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-a-ethyl- Butyric acid, 2-(p-(1-oxo-2-isoindolinyl)phenyl)-, (+-) (±)-4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid (αR)-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid [R,(-)]-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid (αS)-4-[(1,3-Dihydro-1-oxo-2H-isoindol)-2-yl]-α-ethylbenzeneacetic acid d-INB d-Indobufen Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-alpha-ethyl- Ibustrin K-3920 Ibustrin, K 3920 Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl- Indobufen USP/EP/BP 63610-08-2,Indobufen (2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid 2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid Indole cloth Finn Indobufen WRS 2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoicaci Indobuprofen Indobufen, 10 mM in DMSO D5-Indobufen 2-[4-(1-oxy-2-isoindolelineyl)phenyl]butyric acid 63610-08-2 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals 63610-08-2 API