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1-(3-Chlorphenyl)piperazine

1-(3-Chlorphenyl)piperazine
1-(3-Chlorphenyl)piperazine structure
CAS No.
6640-24-0
Chemical Name:
1-(3-Chlorphenyl)piperazine
Synonyms
MCPP;NSC 49307;AKOS BBS-00003580;TIMTEC-BB SBB003579;RARECHEM AH CK 0071;CHLOROPHENYLPIPERAZINE;1,3ChlorofenylPiperazine;m-Chlorophenylpiperazine;3-chlorophenyl piperazine;Metachlorophenyl Piprazine
CBNumber:
CB6325545
Molecular Formula:
C10H13ClN2
Formula Weight:
196.68
MOL File:
6640-24-0.mol

1-(3-Chlorphenyl)piperazine Properties

Melting point:
210-214°C
Boiling point:
105 °C
Density 
1.193
refractive index 
1,598-1,600
storage temp. 
-20°C Freezer, Under Inert Atmosphere
pka
8.85±0.10(Predicted)
CAS DataBase Reference
6640-24-0(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
REY0CNO998
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39-36
Hazard Note  Irritant
HazardClass  IRRITANT
HS Code  29339900

1-(3-Chlorphenyl)piperazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C379590 1-(3-Chlorophenyl)piperazine 6640-24-0 1g $240 2021-12-16 Buy
Frontier Specialty Chemicals JK287024 1-(3-Chlorophenyl)piperazine 98% 6640-24-0 5g $59 2021-12-16 Buy
Frontier Specialty Chemicals JK287024 1-(3-Chlorophenyl)piperazine 98% 6640-24-0 25g $219 2021-12-16 Buy
Medical Isotopes, Inc. 8430 1-(3-Chlorophenyl)piperazine 6640-24-0 25 mg $2000 2021-12-16 Buy
Abosyn 61-3144 1-(3-Chlorophenyl)piperazine 95%-98% 6640-24-0 1g $90 2021-12-16 Buy

1-(3-Chlorphenyl)piperazine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow oily liquid

Uses

It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.

Uses

It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.

Definition

ChEBI: A N-arylpiperazine that is piperazine carrying a 3-chlorophenyl substituent at position 1. It is a metabolite of the antidepressant drug trazodone.

Hazard

A poison.

1-(3-Chlorphenyl)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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