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MMP-9 INHIBITOR I

CAS No.
1177749-58-4
Chemical Name:
MMP-9 INHIBITOR I
Synonyms
MMP-9 Inhibitor;MMP-9 INHIBITOR I;MMP-9 Inhibitor II;MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem;Benzamide, 5-[(diethylamino)methyl]-N-hydroxy-2-[[(4-methoxyphenoxy)sulfinyl](phenylmethyl)amino]-3-methyl-
CBNumber:
CB6666273
Molecular Formula:
C27H33N3O5S
Molecular Weight:
511.63
MDL Number:
MFCD22581508
MOL File:
1177749-58-4.mol
Last updated:2023-05-04 17:34:32

MMP-9 INHIBITOR I Properties

Density 1.276±0.06 g/cm3(Predicted)
storage temp. -20C
form Off-white solid
pka 8.28±0.42(Predicted)

MMP-9 INHIBITOR I Chemical Properties,Uses,Production

Definition

ChEBI: MMP9 inhibitor I is a hydroxamic acid that is N-hydroxy-3-methylbenzamide in which the the hydrogens at positions 2 and 5 have been replaced by benzyl[(4-methoxyphenyl)sulfonyl]amino and (diethylamino)methyl groups, respectively. It is a cell-permeable, potent, selective, and reversible inhibitor of matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35). It has a role as an EC 3.4.24.35 (gelatinase B) inhibitor. It is a hydroxamic acid, a tertiary amino compound, a sulfonamide and an aromatic ether.

General Description

A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 μM) and MMP-13 IC50 = 113 nM) at higher concentrations.

Biochem/physiol Actions

Primary TargetMMP-9

MMP-9 INHIBITOR I Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518 sales@alabiochem.com China 995 59
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
Alabiotech Inc. 001-619-354-5251 sales@alabiotech-e.com United States 972 60
Alpha Biopharmaceuticals Co., Ltd 0411-39042497 sales@alphabiopharm.com China 1951 58
MMP-9 INHIBITOR I MMP-9 Inhibitor II MMP-9 Inhibitor MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem Benzamide, 5-[(diethylamino)methyl]-N-hydroxy-2-[[(4-methoxyphenoxy)sulfinyl](phenylmethyl)amino]-3-methyl- 1177749-58-4