ChemicalBook >> CAS DataBase List >>2,4-Thiazolidinedione
2,4-Thiazolidinedione
- CAS No.
- 2295-31-0
- Chemical Name:
- 2,4-Thiazolidinedione
- Synonyms
- THIAZOLIDINE-2,4-DIONE;TZD;Thiazolidinedione;2,4-Thiazolidindione;U 25560;idinedione;usafek-5496;2,4-ThiazoL;USAF ek-5496;AURORA 23272
- CBNumber:
- CB6675365
- Molecular Formula:
- C3H3NO2S
- Molecular Weight:
- 117.13
- MDL Number:
- MFCD00005478
- MOL File:
- 2295-31-0.mol
- MSDS File:
- SDS
Last updated:2023-11-17 16:09:38
| Melting point | 125-127 °C (lit.) |
|---|---|
| Boiling point | 178-179 °C (19 mmHg) |
| Density | 1.408 (estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.5130 (estimate) |
| Flash point | 178-179°C/19mm |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 6.50±0.10(Predicted) |
| color | Slightly yellow |
| Water Solubility | Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether. |
| BRN | 110700 |
| InChIKey | ZOBPZXTWZATXDG-UHFFFAOYSA-N |
| LogP | -0.29 at 25℃ |
| CAS DataBase Reference | 2295-31-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | AA68LXK93C |
| NIST Chemistry Reference | 2,4-Thiazolidinedione(2295-31-0) |
| EPA Substance Registry System | 2,4-Thiazolidinedione (2295-31-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310a-P321-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XJ5775000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29341000 | |||||||||
| NFPA 704 |
|
2,4-Thiazolidinedione price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 375004 | 2,4-Thiazolidinedione technical grade, 90% | 2295-31-0 | 25g | $79 | 2024-03-01 | Buy |
| Sigma-Aldrich | 375004 | 2,4-Thiazolidinedione technical grade, 90% | 2295-31-0 | 100g | $123 | 2024-03-01 | Buy |
| TCI Chemical | T1990 | 2,4-Thiazolidinedione >98.0%(GC)(T) | 2295-31-0 | 25g | $19 | 2024-03-01 | Buy |
| TCI Chemical | T1990 | 2,4-Thiazolidinedione >98.0%(GC)(T) | 2295-31-0 | 100g | $51 | 2024-03-01 | Buy |
| Alfa Aesar | A13496 | 2,4-Thiazolidinedione, 99% | 2295-31-0 | 25g | $59.65 | 2024-03-01 | Buy |
2,4-Thiazolidinedione Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Powder
Uses
Inhibitor of enzyme
Uses
2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity.
Definition
ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4.
General Description
2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported.
Flammability and Explosibility
Not classified
2,4-Thiazolidinedione Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Global( 599)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from 2,4-Thiazolidinedione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-02 | 2,4-Thiazolidinedione
2295-31-0
|
US $65.00-650.00 / KG | 1KG | 0.99 | 20 tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2023-11-18 | 2,4-Thiazolidinedione
2295-31-0
|
US $30.00-10.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2023-03-31 | 2,4-Thiazolidinedione
2295-31-0
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD |
-
- 2,4-Thiazolidinedione
2295-31-0
- US $65.00-650.00 / KG
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- 2,4-Thiazolidinedione
2295-31-0
- US $30.00-10.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- 2,4-Thiazolidinedione
2295-31-0
- US $5.00-2.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
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2,4-THIZAOLODINE
2,4-Thiazolidinedione >
2,4-Thiazolidinedione (P)
Thiazolidin-2,4-dion
TZD
THIAZOLIDINE-2,4-DIONE
Thiazolidinedione
2,4-Thiazolidindione
Thiazolidinedione (6CI)
Pioglitazone impurity
thiazolidine-2,4-dione
2295-31-0
2295-31-2
C3H3NO2S
C3H2KNO2S
Building Blocks
Heterocyclic Building Blocks
Thiazoles
Thiazolines/Thiazolidines
Starting Raw Materials & Intermediates
PHARMACEUTICAL INTERMEDIATES
Sulphur Derivatives
Sulfur compounds
blocks
Heterocycles