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2-Methoxyethanol structure
Chemical Name:
H2O;EGM;Egme;MECS;Prist;WATER G;dowanol7;TAP-WATER;SOLVENT S;dowanolem
Molecular Formula:
Formula Weight:
MOL File:

2-Methoxyethanol Properties

Melting point:
-85 °C
Boiling point:
124-125 °C(lit.)
0.965 g/mL at 25 °C(lit.)
vapor density 
2.62 (vs air)
vapor pressure 
6.17 mm Hg ( 20 °C)
refractive index 
n20/D 1.402(lit.)
Flash point:
115 °F
storage temp. 
15.7(at 25℃)
green cap
Relative polarity
Mild ethereal.
explosive limit
Water Solubility 
λ: 213 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 260 nm Amax: 0.05
λ: 300-400 nm Amax: 0.01
Exposure limits
TLV-TWA skin 5 ppm (15.5 mg/m3) (ACGIH), 25 ppm (77.5 mg/m3) (OSHA).
Stable, but contact with air may lead to the formation of explosive peroxides. A peroxide test should be carried out before this material is used if it has been exposed to air for some time, especially if it is to be purified by distillation. Contact with strong oxidizing agents may cause fire or explosion. Incompatible with strong bases, ac
CAS DataBase Reference
109-86-4(CAS DataBase Reference)
NIST Chemistry Reference
Ethanol, 2-methoxy-(109-86-4)
EPA Substance Registry System
Ethanol, 2-methoxy-(109-86-4)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T,F,C
Risk Statements  60-61-10-20/21/22-39/23/24/25-23/24/25-11-35-34-36/38
Safety Statements  53-45-36/37-16-26-23-36/37/39
RIDADR  UN 1188 3/PG 3
WGK Germany  3
RTECS  ZC0110000
Autoignition Temperature 548 °F
HazardClass  3
PackingGroup  III
HS Code  29332990
Hazardous Substances Data 109-86-4(Hazardous Substances Data)
Toxicity LD50 in rats, guinea pigs (mg/kg): 2460, 950 orally (Smyth); LC50 (7 hr in air) in mice: 4.6 mg/l (Werner)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.

2-Methoxyethanol price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1601645 Residual Solvent Class 2 - 2-Methoxyethanol Pharmaceutical Secondary Standard; Certified Reference Material 109-86-4 3x1.2ml $67.5 2018-11-13 Buy
Sigma-Aldrich 185469 2-Methoxyethanol ReagentPlus , ≥99.0%, contains 50 ppm BHT as stabilizer 109-86-4 4l $209 2018-11-13 Buy
TCI Chemical M0111 2-Methoxyethanol (stabilized with BHT) >99.0%(GC) 109-86-4 25mL $17 2018-11-22 Buy
TCI Chemical M0111 2-Methoxyethanol (stabilized with BHT) >99.0%(GC) 109-86-4 500mL $28 2018-11-22 Buy
Alfa Aesar 031733 2-Methoxyethanol, ACS, 99.3+% 109-86-4 *4x4L $449 2018-11-16 Buy

2-Methoxyethanol Chemical Properties,Uses,Production

Chemical Properties

Ethylene glycol monomethyl ether is a colorless, limpid liquid of mild odor. It is miscible with water and with aliphatic and aromatic hydrocarbons. It is a solvent for essential oils, lignin, dammar, Elemi Essential Oil, ester gum, kauri, mastic, rosin, sandarac resin, shellac, Zanzibar, nitrocellulose, cellulose acetate, alcohol-soluble dyes and many synthetic resins. Its solvency far cellulose esters is augmented when a ketone or a halogenated hydrocarbon i s added. The uses for methyl "Cellosolve" are as a solvent in quick-drying varnishes and enamels, in conjunction with aliphatic, aromatic and halogenated hydrocarbons, alcohols and ketones; in solvent mixtures and thinners for lacquers and dopes; in the manufacture of synthetic resin plasticizers and as a penetrating and leveling agent in dyeing processes, especially in the dyeing of leather, animal and vegetable fibers. Other uses are as o fixative in perfumes and as a solvent in odorless nail-polish lacquers. "Dowanol EM" should not be added to nitrocellulose lacquers containing coumarone resins or ester gum because it will cause incompatibility between these substances.

Chemical Properties

Ethylene glycol monomethyl ether is a colorless liquid with a slight ethereal odor. The Odor Threshold is 0.92.3 ppm.


ethylene glycol monomethyl ether (ethoxyethanol) is considered a non-comedogenic raw material. It is used as a solvent in nail products and as a stabilizer in cosmetic emulsions. It is able to penetrate the skin and may cause skin irritation.


The primary use of this compound is as asolvent for cellulose acetate, certain syntheticand natural resins, and dyes. Other applications are in jet fuel deicing, sealing moisture-proof cellophane, dyeing leather, and use innail polishes, varnishes, and enamels.


ChEBI: A hydroxyether that is ethanol substituted by a methoxy group at position 2.


Solvent for low-viscosity cellulose acetate, natural resins, some synthetic resins and some alcohol-soluble dyes; in dyeing leather, sealing moistureproof cellophane; in nail polishes, quick-drying varnishes and enamels, wood stains. In modified Karl Fischer reagent: Peters, Jungnickel, Anal. Chem. 27, 450 (1955).

General Description

A clear colorless liquid. Flash point of 110°F. Less dense than water. Vapors are heavier than air.

Air & Water Reactions

Flammable. Water soluble.

Reactivity Profile

2-Methoxyethanol is incompatible with oxygen and strong oxidizing agents. Contact with bases may result in decomposition. Incompatible with acid chlorides and acid anhydrides. . 2-Methoxyethanol forms explosive peroxides.


Toxic by ingestion and inhalation. Moderate fire risk. Toxic by skin absorption. Questionable carcinogen.

Health Hazard

Irritation of skin and eyes. Chronic exposure may also cause weakness, sleepiness, headache, gastrointestinal upset, weight loss, change of personality.

Health Hazard

Ethylene glycol monomethyl ether (EGME)is a teratogen and a chronic inhalation toxicant. The target organs are blood, kidney,and the central nervous system. In addi tion to inhalation, the other routes of expo sure are absorption through the skin, and ingestion. Animal studies indicated that over-exposure to this compound produced anemia, hematuria, and damage to the testes.In humans, inhalation of EGME vapors cancause headache, drowsiness, weakness, irrita tion of the eyes, ataxia, and tremor. The acuteinhalation toxicity, however, is low and anytoxic effect may be felt at a concentration ofabout 25–30 ppm in air
The oral and dermal toxicities of thiscompound in test animals were found to belower than the inhalation toxicity. Ingestioncan produce an anesthetic effect and in alarge dosage can be fatal. An oral intake ofabout 200 mL may cause death to humans.
LC50 value (mice): 1480 ppm/7 h,
LD50 value (rabbits): 890 mg/kg
EGME is a teratogen exhibiting fetotoxi city, affecting the fertility and the litter size,and causing developmental abnormalities inthe urogenital and musculoskeletal systemsin test animals.

Fire Hazard

Flash Point (°F): 120 ℃; 107 ℃; Flammable Limits in Air (%): 2.5-19.8; Fire Extinguishing Agents: Dry chemical, carbon dioxide or alcohol foam; Fire Extinguishing Agents Not To Be Used: Not pertinent; Special Hazards of Combustion Products: Not pertinent; Behavior in Fire: Not pertinent; Ignition Temperature (°F): 551; Electrical Hazard: Not pertinent; Burning Rate: 1.8 mm/min.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Safety Profile

Moderately toxic to humans by ingestion. Moderately toxic experimentally by ingestion, inhalation, shin contact, intraperitoneal, and intravenous routes. Human systemic effects by inhalation: change in motor activity, tremors, and convulsions. Experimental teratogenic and reproductive effects. A skin and eye irritant. Mutation data reported. When used under conditions that do not require the application of heat, thts material probably presents little hazard to health. However, in the manufacture of fused collars which require pressing with a hot iron, cases have been reported showing disturbance of the hemopoietic system with or without neurologcal signs and symptoms. The blood picture may resemble that produced by exposure to benzene. Two cases reported had severe aplastic anemia with tremors and marked mental dullness. The persons affected had been exposed to vapors of methyl "Cellosolve," ethanol, methanol, ethyl acetate, and petroleum naphtha. flame. A moderate explosion hazard. Can react with oxidizing materials to form explosive peroxides. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS. Flammable liquid when exposed to heat or

Potential Exposure

Ethylene glycol monomethyl ether is used as a jet fuel additive; solvent for protective coating; and in chemical synthesis. Ethylene glycol ethers are used as solvents for resins used in the electronics industry, lacquers, paints, varnishes, gum, perfume; dyes and inks; and as a constituent of painting pastes, cleaning compounds; liquid soaps; cosmetics, nitrocellulose, and hydraulic fluids

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy


UN1188 Ethylene glycol monomethyl ether, Hazard Class: 3; Labels: 3-Flammable liquid

Purification Methods

Peroxides can be removed by refluxing with stannous chloride or by filtration under slight pressure through a column of activated alumina. 2-Methoxyethanol can be dried with K2CO3, CaSO4, MgSO4 or silica gel, then distilled from sodium. Aliphatic ketones (and water) can be removed by making the solvent 0.1% in 2,4-dinitrophenylhydrazine and allowing to stand overnight with silica gel before fractionally distilling. [Beilstein 1 IV 2375.]


Vapors may form explosive mixture with air. Heat or oxidizers may cause the formation of unstable peroxides. Attacks many metals. Strong oxidizers may cause fire and explosions. Strong bases cause decomposition and the formation of toxic gas. Attacks some plastics, rubber and coatings. May accumulate static electrical charges, and may cause ignition of its vapors.

Waste Disposal

Concentrated waste containing no peroxides: discharge liquid at a controlled rate near a pilot flame. Concentrated waste containing peroxides: perforation of a container of the waste from a safe distance followed by open burning.

2-Methoxyethanol Preparation Products And Raw materials

Raw materials

Preparation Products

2-Methoxyethanol Suppliers

Global( 279)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20229 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4558 58
Yancheng Green Chemicals Co.,Ltd
86-515-87883652 CHINA 351 58
career henan chemical co
+86-371-86658258 CHINA 19997 58
13867897135 CHINA 930 58
Shanghai Macklin Biochemical Co.,Ltd. 15221275939
021-51821727 China 15820 55

View Lastest Price from 2-Methoxyethanol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-05 2-Methoxyethanol Factory 1ppb
US $1.00 / kg 1kg Heavy metal < 1-10 ppb High quality Factory Chemwill Asia Co.,Ltd.
2018-12-22 2-Methoxyethanol
US $1.00 / kg 1kg 99% Customized career henan chemical co

2-Methoxyethanol Spectrum

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