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2-Butoxyethanol structure
Chemical Name:
BuCs;egbe;2-be;butycel;gafcoleb;a13-0993;chimecnr;Gafcol EB;Minex BDH;Chimec NR
Molecular Formula:
Formula Weight:
MOL File:

2-Butoxyethanol Properties

Melting point:
-70 °C
Boiling point:
171 °C
0.902 g/mL at 25 °C(lit.)
vapor density 
4.1 (vs air)
vapor pressure 
<1 mm Hg ( 20 °C)
refractive index 
n20/D 1.419(lit.)
Flash point:
140 °F
storage temp. 
Store at room temperature.
900g/l completely miscible
7 (H2O, 20℃)(as aqueous solution)
Mild, characteristic; slightly rancid; mild ethereal.
explosive limit
Water Solubility 
λ: 230 nm Amax: 1.0
λ: 250 nm Amax: 0.10
λ: 275 nm Amax: 0.05
λ: 300-400 nm Amax: 0.01
Exposure limits
TLV-TWA skin 25 ppm (121 mg/m3) (ACGIH), 50 ppm (242 mg/m3) (OSHA); STEL 75 ppm (363 mg/m3) (ACGIH);IDLH 700 ppm (NIOSH). .
CAS DataBase Reference
111-76-2(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
Ethanol, 2-butoxy-(111-76-2)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  Xn
Risk Statements  20/21/22-36/38
Safety Statements  36/37-46
RIDADR  1986
WGK Germany  1
RTECS  KJ8575000
Autoignition Temperature 473 °F
HS Code  2909 43 00
HazardClass  6.1
PackingGroup  III
Hazardous Substances Data 111-76-2(Hazardous Substances Data)
Toxicity LD50 orally in rats: 1.48 g/kg (Smyth)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

NFPA 704

Diamond Hazard Value Description
3 0
Health   3 Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
Flammability   2 Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)

(NFPA, 2010)

2-Butoxyethanol price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 256366 Ethylene glycol butyl ether spectrophotometric grade, ≥99.0% 111-76-2 1l $117 2018-11-13 Buy
Sigma-Aldrich 256366 Ethylene glycol butyl ether spectrophotometric grade, ≥99.0% 111-76-2 2l $176 2018-11-13 Buy
TCI Chemical B0698 Ethylene Glycol Monobutyl Ether >99.0%(GC) 111-76-2 25mL $14 2018-11-22 Buy
TCI Chemical B0698 Ethylene Glycol Monobutyl Ether >99.0%(GC) 111-76-2 500mL $17 2018-11-22 Buy
Alfa Aesar A17976 2-n-Butoxyethanol, 99% 111-76-2 500ml $21 2018-11-15 Buy

2-Butoxyethanol Chemical Properties,Uses,Production


2-Butoxyethanol is a clear, colourless liquid with ether-like smell.2-Butoxyethanol is usually produced by a reaction of ethylene oxide with butyl alcohol, but it may also be made by the reaction of ethylene glycol with dibutyl sulphate. 2-Butoxyethanol is widely used as a solvent in protective surface coatings such as spray lacquers, quick-dry lacquers, enamels, varnishes, and latex paints. It is also used as an ingredient in paint thinners and strippers, varnish removers, agricultural chemicals, herbicides, silicon caulks, cutting oils, and hydraulic fluids and as metal cleaners, fabric dyes and inks, industrial and household cleaners (as a degreaser), and dry-cleaning compounds. It is also used in liquid soaps and in cosmetics. 2-Butoxyethanol acetate has been reported to be present in air, water, and soil as a contaminant and exposure to it occurs during its manufacture and use as an intermediate in the chemical industry, and during the formulation and use of its products in multiple industrial activities. The acetate form of 2-butoxyethanol is 2-butoxyethanol acetate and also known as ethylene glycol monobutyl ether acetate.

Chemical Properties

Ethylene glycol monobutyl ether is colorless liquid, miscible in alI proportions with many ketones, ethers, alcohols, aromatic paraffin and halogenated hydrocarbons. More specifically, it mixes in all proportions with acetone, benzene, carbon tetrachloride, ethyl ether, n-heptane and water. Because of its excellent solvency, low evaporation rate and high dilution ratios, it is used as a solvent in the manufacture and formulation of lacquers, enamels, inks and varnishes, employing such resins as alkyd, phenolic, nitrocellulose, maleic modified, styrene and epoxy. In lacquers butyl "Cellosolve" imparts a slow evaporation rate, strengthens blush resistance, heightens gloss, improves flow-out and helps prevent orange peel. Hot spray lacquers usually contain about 10% of "Dowanol" EB based on the solvent-diluent weight.

Chemical Properties

2-Butoxyethanol is a clear colorless liquid with an ether-like smell and belongs to the fam ily of glycol ether/alkoxy alcohol. 2-Butoxyethanol is miscible in water and soluble in most organic solvents. 2-Butoxyethanol does not occur naturally. It is usually produced by reacting ethylene oxide with butyl alcohol. It is used as a solvent for nitrocellulose, natural and synthetic resins, soluble oils, in surface coatings, spray lacquers, enamels, varnishes, and latex paints, as an ingredient in paint thinners, quick-dry lacquers, latex paint, and strippers, varnish removers, and herbicides. 2-Butoxyethanol is also used in textile dyeing and printing, in the treatment of leather, in the production of plasticizers, as a stabilizer in metal cleaners and household cleaners, and in hydraulic fl uids, insecticides, herbicides, and rust removers. It is also used as an ingredient in liquid soaps, cosmetics, industrial and household cleaners, dry-cleaning compounds, and as an ingredient in silicon caulks, cutting oils, and hydraulic fl uids. 2-Butoxyethanol is a fi re hazard when exposed to heat, sparks, or open flames

Chemical Properties

Ethylene glycol monobutyl ether is a colorless liquid with a mild, rancid, ether-like odor. It is soluble in most organic solvents and mineral oil. It mixes with acetone, benzene, carbon tetrachloride, ethyl ether, n-heptane and water; it is miscible with many ketones, ethers, alcohols, aromatic paraffin, and halogenated hydrocarbons.


Ethylene glycol n-butyl ether (EB) is used widely as a coupling solvent because of its superior coupling efficiency and excellent solvency for resins.


Ethylene glycol monobutyl ether (EGBE) is used as a solvent for nitrocellulose, resins, oil, and grease, and in dry cleaning.


Solvent for nitrocellulose, resins, grease, oil, albumin; dry cleaning.

General Description

A colorless liquid with a mild, pleasant odor. Less dense than water. Flash point 160°F. Irritates skin and eyes and may be toxic by ingestion. Used as a solvent and to make paints and varnish.

Air & Water Reactions

2-Butoxyethanol is sensitive to air and light. Slightly soluble in water.

Reactivity Profile

ETHYLENE GLYCOL N-BUTYL ETHER may react with bases, aluminum and oxidizing materials. 2-Butoxyethanol is liable to form peroxides on exposure to air and light. 2-Butoxyethanol attacks some forms of plastics, rubber and coatings. .


A toxic material. Eye and upper respiratory tract irritant. Questionable carcinogen.

Health Hazard

Vapors irritate eyes and nose. Ingestion or skin contact causes headache, nausea, vomiting, dizziness.

Health Hazard

2-Butoxyethanol is present in a variety of consumer products, including cleaning agents and surface coatings, such as paints, lacquers, and varnishes. 2-Butoxyethanol is readily absorbed following inhalation, oral, and dermal exposure. 2-Butoxyethanol is released into air or water by different industrial activities and facilities that manu facture, process, or use the chemical. Exposure to 2-butoxyethanol causes irritating effects to the eyes and skin, but it has not induced skin sensitization in guinea pigs. Information on the human health effects associated with exposure to 2-butoxyethanol is limited. However, case studies of individuals who had attempted suicide by ingest ing 2-butoxyethanol-containing cleaning solutions suffered poisoning with symp toms such as hemoglobinuria, erythropenia, and hypotension, metabolic acidosis, shock, non-cardiogenic pulmonary edema, and albuminuria, hepatic disorders and hematuria.

Health Hazard

EGBE exhibited mild to moderate toxicity in test animals. The toxic symptoms are similar to those of EGME. It is an irritant to the eyes and skin. The toxic routes of exposure are inhalation, ingestion, and absorption through the skin. In animals, prolonged exposure to high concentrations or high oral intake caused hematuria, kidney damage, and increased osmotic fragility of the blood cells. Such effects, however, were noted only at a high level of exposures (i.e., 700 ppm for 7 hours in mice, the minimal lethal concentration) (Werner et al. 1943). The other toxic effects noted were respiratory distress, change in motor activity, and lung, kidney, and liver changes. EGBE is absorbed rapidly through the skin. A 3-minute contact with 0.56 mL/kg over a 4.5% skin area produced the increased red blood cell fragility within an hour in rabbits (Carpenter et al. 1956; ACGIH 1986). Rabbits treated percutaneously with 0.08 to 0.25 mL/kg EGBE developed prostration, hypothermia, hemoglobinuria, spleen congestion, and kidney enlargement (Duprat and Gradiski 1979). Some rabbits survived and did not show the foregoing histopathological signs. The percutaneous toxicity of EGBE was found to be greater than that of the industrial solvents carbon tetrachloride and dimethyl formamide but lower than that of 2-chloroethanol and 1,1,2-trichloroethane (Wahlberg and Boman 1979). Chronic exposures at lower concentrations produced mild hemolytic anemia and thymic atrophy in rats (Grant et al. 1985). Subchronic oral doses of undiluted EGBE produced a significant dosedependent decrease in the blood hemoglobin concentration (Krasavage 1986). Such an effect was manifested at the moderately high dose of 222–885 mg/kg/day for 5 days/week over a 6-week period. No adverse effects on the testes, bone marrow, thymus, or white blood cells were observed
LC50 value, (rats): 450 ppm/4 h
LD50 value, oral (rats): 530 mg/kg
In humans the toxic effects of EGBE are generally low. Exposure to 200 ppm for 8 hours may produce nausea, vomiting, and headache. In a study on male volunteers exposed to 20 ppm of EGBE for 2 hours during light physical exercise, Johansson and coworkers (1986) determined that the respiratory uptake of EGBE was about 57% of the inspired amount; its concentration in the blood reached a plateau level of 0.87 mg/L; the elimination half-time and the mean residence time were 40 and 42 minutes, respectively. The amount excreted in the urine was <0.03% of the total intake, whereas that of butoxyacetic acid ranged from 17 to 55%.
Noreproductivetoxicity hasbeenreported in male animals. No teratogenic effects have been reported in females. However, when pregnant animals received high oral or inhalation doses of this material, signs of embryo–fetal toxicity were reported but only at doses that were maternally toxic. Unlike EGME, EGBE caused no testicular atrophy (Doe 1984; Nagano et al. 1984).

Fire Hazard

Flash Point (°F): 165 ℃; 155 ℃; Flammable Limits in Air (%): 1.1-10.6; Fire Extinguishing Agents: Carbon dioxide or dry chemical for small fires; alcohol-type foam for large fires; Fire Extinguishing Agents Not To Be Used: Data not available; Special Hazards of Combustion Products: Not pertinent; Behavior in Fire: Not pertinent; Ignition Temperature (°F): 472; Electrical Hazard: Not pertinent; Burning Rate: 6.7 mm/min.

Fire Hazard

Combustible material: may burn but does not ignite readily. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Safety Profile

Poison by ingestion, skin contact, intraperitoneal, and intravenous routes. Moderately toxic via inhalation and subcutaneous routes. Human systemic effects by inhalation: nausea or vomiting, headache, unspecified eye effects. Experimental teratogenic and reproductive effects. A skin irritant. Combustible liquid when exposed to heat or flame. To fight fire, use foam, CO2, dry chemical. Incompatible with oxidizing materials, heat, and flame. When heated to decomposition it emits acrid smoke and irritating fumes

Potential Exposure

2-Butoxy ethanol is a colorless liquid with a mild, ether like odor. Molecular weight 5 118.20; Specific gravity (H2O:1) 5 0.90; boiling point 5 171C; freezing/ melting point 5 274.8C; vapor pressure 5 0.8 mmHg @ 20C; Relative vapor density (air 5 1) 5 4.1; Flash point = 61C (cc); Autoignition temperature = 238C

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy


2-Butoxyethanol should be kept stored in tightly closed, grounded containers in a cool area with adequate ventilation, away from normal work areas and sources of heat and sparks, and electrical equipment. At the storage and handling area, workers should use solvent resistant materials.

Purification Methods

Peroxides can be removed by refluxing with anhydrous SnCl2 or by passage under slight pressure through a column of activated alumina. Dry with anhydrous K2CO3 and CaSO4, filter and distil, or reflux with, and distil from NaOH. [Beilstein 1 IV 2380.]


May form explosive mixture with air. Can form unstable and explosive peroxides; check for peroxides prior to distillation; render harmless if positive. Decomposes, producing toxic fumes. Violent reaction with strong caustics and strong oxidizers. Attacks some coatings, plastics and rubber. Attacks metallic aluminum at high temperatures.

Waste Disposal

EGBE is destroyed by burning in an incinerator. In the laboratory, small amounts may be disposed of in the sink with a large volume of water.


Occupational workers should use minimal quantities of 2-butoxyethanol in designated areas with adequate ventilation and away from sources of heat or sparks. Whenever pos sible, fi re-resistant containers should be used. Wear appropriate protective equipment to prevent skin and eye contact.

2-Butoxyethanol Preparation Products And Raw materials

Raw materials

Preparation Products

2-Butoxyethanol Suppliers

Global( 266)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 1730 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24001 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20095 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4669 58
career henan chemical co
+86-371-86658258 CHINA 20104 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40277 62
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 China 30168 84

View Lastest Price from 2-Butoxyethanol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-05 2-Butoxyethanol Factory
US $1.00 / kg 1kg Heavy metal < 1-10 ppb High quality Factory Chemwill Asia Co.,Ltd.
2019-04-04 2-Butoxyethanol; Ethyleneglycol monobutyl ether in stock Factory
US $1.00 / kg 1kg High quality purified manufacturer Top 3 production capacity Factory Chemwill Asia Co.,Ltd.
2018-12-18 2-Butoxyethanol
US $1.00 / kg 1kg as customer's need 500kg career henan chemical co

2-Butoxyethanol Spectrum

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