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Abacavir 5’-Phosphate

Abacavir 5’-Phosphate structure

CAS No.: 136470-77-4

Chemical Name:: Abacavir 5’-Phosphate

Synonyms: Abacavir Impurity 13;Abacavir 5’-Phosphate;(1S-cis)-Abacavir Monophosphate;[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate;((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)-;(1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester)

CBNumber:: CB72502992

Molecular Formula:: C14H19N6O4P

Molecular Weight:: 366.31

MDL Number:: MFCD23160255

MOL File:: 136470-77-4.mol

Last updated:2023-05-04 17:34:33

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Abacavir 5’-Phosphate Properties

Melting point	189-194°C (dec.)
Boiling point	749.3±70.0 °C(Predicted)
Density	1.93±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Methanol, Water
pka	1.91±0.10(Predicted)
form	Solid
color	White
FDA UNII	6I6AN9D95R

Abacavir 5’-Phosphate price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A105020	Abacavir5’-Phosphate	136470-77-4	1mg	$90	2021-12-16	Buy
TRC	A105020	Abacavir5’-Phosphate	136470-77-4	10mg	$625	2021-12-16	Buy
Biosynth Carbosynth	NA16495	Abacavir 5'-phosphate	136470-77-4	5mg	$1051.1	2021-12-16	Buy
AK Scientific	3389CC	Abacavir5'-phosphate	136470-77-4	5mg	$1468	2021-12-16	Buy
Biosynth Carbosynth	NA16495	Abacavir 5'-phosphate	136470-77-4	10mg	$1911	2021-12-16	Buy

Product number	Packaging	Price	Buy
A105020	1mg	$90	Buy
A105020	10mg	$625	Buy
NA16495	5mg	$1051.1	Buy
3389CC	5mg	$1468	Buy
NA16495	10mg	$1911	Buy

Abacavir 5’-Phosphate Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Definition

ChEBI: Abacavir monophosphate is the organic phosphate that is the 5'-monophosphate of abacavir. It has a role as a metabolite. It is a member of 2,6-diaminopurines and an organic phosphate. It is functionally related to an abacavir.

Abacavir 5’-Phosphate Preparation Products And Raw materials

Raw materials

Preparation Products

Abacavir 5’-Phosphate Suppliers

Global( 20)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10026	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9685	58
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Beijing Minruida Technology Co., Ltd.	010-82387566 18001021521;	sales@mreda.com.cn	China	21450	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55717	58
Shenzhen Botel Biotechnology Co. Ltd.	0755-22202135 13316968096	1979313431@qq.com	China	7642	58

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
NewCan Biotech Limited	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
BOC Sciences	65
Clearsynth Labs Limited	58
BOC Sciences	65
Beijing Minruida Technology Co., Ltd.	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Shenzhen Botel Biotechnology Co. Ltd.	58

136470-77-4(Abacavir 5’-Phosphate)Related Search:

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Abacavir 5’-Phosphate (1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester) (1S-cis)-Abacavir Monophosphate [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate ((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)- Abacavir Impurity 13 136470-77-4 C14H19N6O4P Bases & Related Reagents Intermediates & Fine Chemicals Metabolites & Impurities Nucleotides Pharmaceuticals Phosphorylating and Phosphitylating Agents