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Thymopentin

Thymopentin structure

CAS No.: 69558-55-0

Chemical Name:: Thymopentin

Synonyms: TP-5;RKDVY;Immunox;Timunox;ORF-15244;THYMOPETIN;Thyopentin;THYMOPENTIN;Thymopentine;ThymopentinⅡ

CBNumber:: CB7491069

Molecular Formula:: C30H49N9O9

Molecular Weight:: 679.77

MDL Number:: MFCD00214200

MOL File:: 69558-55-0.mol

Last updated:2023-11-15 17:17:25

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Thymopentin Properties

Density	1.44±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
pka	3.07±0.10(Predicted)
form	Powder
color	White
CAS DataBase Reference	69558-55-0(CAS DataBase Reference)
FDA UNII	O3Y80ZF13F
NCI Drug Dictionary	Immunox
ATC code	L03AX09

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P330-P501

WGK Germany

HS Code

3504009000

NFPA 704

	0
2		0

Thymopentin price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T8806	Thymopentin ≥97% (HPLC)	69558-55-0	10mg	$235	2024-03-01	Buy
Alfa Aesar	J61431	Thymopentin 99+%	69558-55-0	25mg	$117	2023-06-20	Buy
Alfa Aesar	J61431	Thymopentin 99+%	69558-55-0	100mg	$257	2021-12-16	Buy
Cayman Chemical	30119	Thymopentin	69558-55-0	5mg	$37	2024-03-01	Buy
Cayman Chemical	30119	Thymopentin	69558-55-0	10mg	$62	2024-03-01	Buy

Product number	Packaging	Price	Buy
T8806	10mg	$235	Buy
J61431	25mg	$117	Buy
J61431	100mg	$257	Buy
30119	5mg	$37	Buy
30119	10mg	$62	Buy

Thymopentin Chemical Properties,Uses,Production

Description

Thymopentin is a kind of peptide. Peptides and polypeptides play a critical role in the immune system and are therefore predestined as a source for new approaches in immunotherapy. Thymopentin is capable of modulating the immune response. It is a fragment of the thymopoietins (TMPOs) which is a family of nuclear protein. Studies have shown that Thymopentin is capable of affecting the function of T cells and monocytes monitored by increased cGMP level and the triggering of cellular signaling. It is also capable of improve an imbalanced immune system. As an immunomodulating agent, it is clinically used in the treatment of autoimmune diseases such as atopic dermatitis, chronic lymphocytic leukemia, Sezary’s syndrome, rheumatoid arthritis and decreased immune competency. Recent study has also shown that its immuno-modulating effect can also help fight against the infection of mycobacterium tuberculosis.

Originator

Janssen (Belgium)

Uses

Thymopentin Acetate (TP-5) is a synthetic immunomodulating pentapeptide.

Uses

immunoregulator

Definition

ChEBI: Thymopentin is an oligopeptide.

brand name

SINTOMODULINA; TIMUNOX

Clinical Use

Thymopentin is a synthetic, immunomodulating pentapeptide, representing the active fragment of the thymus hormone, thymopoietin. Thymopentin induces phenotypic differentiation and maturation of T-cells. It appears of value in the treatment of primary immune deficiency, rheumatoid arthritis, atopic dermatitis, sarcoidosis and a variety of other diseases with manifestations of disturbed immune balance.

References

Zhang, Yan, et al. "Novel thymopentin release systems prepared from bioresorbable PLA–PEG–PLA hydrogels." International journal of pharmaceutics 386.1 (2010): 15-22.
Gonser, S., E. Weber, and G. Folkers. "Peptides and polypeptides as modulators of the immune response: thymopentin—an example with unknown mode of action." Pharmaceutica Acta Helvetiae 73.6 (1999): 265-273.
Wang, Ying, et al. "Synthetic modifications of the immunomodulating peptide thymopentin to confer anti-mycobacterial activity." Biomaterials 35.9 (2014): 3102-3109.

Thymopentin Preparation Products And Raw materials

Raw materials

AMBERLITE(R) IRC-50 SEPHADEX G-75 ANION EXCHANGE RESIN 717

Preparation Products

Thymopentin Suppliers

Global( 394)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tengmao Chemical Technology Co. LTD	+8615238638457	salesvip2@hntmhg.com	China	415	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Beijing Yibai Biotechnology Co., Ltd	0086-182-6772-3597	sales04@yibaibiotech.com	CHINA	419	58

Supplier	Advantage
Henan Tengmao Chemical Technology Co. LTD	58
Nantong Guangyuan Chemicl Co,Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Beijing Yibai Biotechnology Co., Ltd	58

View Lastest Price from Thymopentin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-22	Thymopentin 69558-55-0	US $0.00 / KG	2KG	99% up	20tons	Sinoway Industrial co., ltd.
2024-03-08	Thymopentin 69558-55-0	US $10.00 / kg	1kg	99%	1000kg	Nantong Guangyuan Chemicl Co,Ltd
2023-11-30	Thymopentin 69558-55-0	US $220.00-210.00 / kilograms	1kilograms	99%	500tons	Henan Tengmao Chemical Technology Co. LTD

Thymopentin
69558-55-0
US $0.00 / KG
99% up
Sinoway Industrial co., ltd.

Thymopentin
69558-55-0
US $10.00 / kg
99%
Nantong Guangyuan Chemicl Co,Ltd

Thymopentin
69558-55-0
US $220.00-210.00 / kilograms
99%
Henan Tengmao Chemical Technology Co. LTD

69558-55-0(Thymopentin)Related Search:

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32-36-Thymopoietin L-Arg-L-Lys-L-Asp-L-Val-L-Tyr-OH Thymopoietin II-(32-36) ThyMopentin for Injection TP-5 THYMOPENTIN THYMOPENTIN 5 THYMOPOIETIN (32-36) (HUMAN, MOUSE) THYMOPOIETIN II FRAGMENT (32-36) THYMOPOIETIN I/II (32-36) (BOVINE) THYMOPOIETIN PENTAPEPTIDE Immunox Sintomodulina Thymopentin-FITC Thymopoietin 32-36 Timunox ARG-LYS-ASP-VAL-TYR (ASP34)-THYMOPOIETIN III (32-36) (BOVINE) H-ARG-LYS-ASP-VAL-TYR-OH RKDVY TP-5（Thymopentin） Thymopentin TP-5 Thymopentine THYMOPETIN Arg-Lys-Asp-Val-Tyr-OH Thymopoietin pentapeptide-Fluorescin-isothiocyanate thymopentin pentapeptide Thyopentin Thymopent njection ThymopentinⅡ Sibuxintramine TP-5 / Thymopentin GMP (CFDA) CAS L-Tyrosine, L-arginyl-L-lysyl-L-α-aspartyl-L-valyl- (6S,9S,12S,15S,18S)-1,6-Diamino-9-(4-aminobutyl)-12-(carboxymethyl)-18-(4-hydroxybenzyl)-1-imino-15-isopropyl-7,10,13,16-tetraoxo-2,8,11,14,17-pentaazanonadecan-19-oic acid Thymopentin USP/EP/BP NH2-RKDVY-OH 69558-55-0 Thymopentin Thymopeptide ORF 15244 ORF15244 ORF-15244 TP 5 Thymopoietin pentapeptide 69558-55-0 9558-55-0 C30H49N9O9 C265H397O67N73 BioChemical Amino Acids and Peptides Biochemicals and Reagents Peptides Other Peptides 多肽 Inhibitors IMMUNOX Peptide Amino Acid Derivatives