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Thymopentin

Thymopentin
Thymopentin structure
CAS No.
69558-55-0
Chemical Name:
Thymopentin
Synonyms
TP-5;RKDVY;Immunox;Timunox;THYMOPETIN;THYMOPENTIN;Thymopentine;THYMOPENTIN 5;Sintomodulina;Thymopentin TP-5
CBNumber:
CB7491069
Molecular Formula:
C10H14OSn
Formula Weight:
268.93
MOL File:
69558-55-0.mol

Thymopentin Properties

storage temp. 
−20°C
form 
Powder
color 
White
CAS DataBase Reference
69558-55-0(CAS DataBase Reference)

SAFETY

WGK Germany  3

Thymopentin price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T8806 Thymopentin ≥97% (HPLC) 69558-55-0 10mg $175 2018-11-20 Buy
Alfa Aesar J61431 Thymopentin 99+% 69558-55-0 100mg $258 2018-11-20 Buy
Alfa Aesar J61431 Thymopentin 99+% 69558-55-0 25mg $98.8 2018-11-20 Buy

Thymopentin Chemical Properties,Uses,Production

Description

Thymopentin is a kind of peptide. Peptides and polypeptides play a critical role in the immune system and are therefore predestined as a source for new approaches in immunotherapy. Thymopentin is capable of modulating the immune response. It is a fragment of the thymopoietins (TMPOs) which is a family of nuclear protein. Studies have shown that Thymopentin is capable of affecting the function of T cells and monocytes monitored by increased cGMP level and the triggering of cellular signaling. It is also capable of improve an imbalanced immune system. As an immunomodulating agent, it is clinically used in the treatment of autoimmune diseases such as atopic dermatitis, chronic lymphocytic leukemia, Sezary’s syndrome, rheumatoid arthritis and decreased immune competency. Recent study has also shown that its immuno-modulating effect can also help fight against the infection of mycobacterium tuberculosis.

Originator

Janssen (Belgium)

Uses

immunoregulator

brand name

SINTOMODULINA; TIMUNOX

Clinical Use

Thymopentin is a synthetic, immunomodulating pentapeptide, representing the active fragment of the thymus hormone, thymopoietin. Thymopentin induces phenotypic differentiation and maturation of T-cells. It appears of value in the treatment of primary immune deficiency, rheumatoid arthritis, atopic dermatitis, sarcoidosis and a variety of other diseases with manifestations of disturbed immune balance.

References

Zhang, Yan, et al. "Novel thymopentin release systems prepared from bioresorbable PLA–PEG–PLA hydrogels." International journal of pharmaceutics 386.1 (2010): 15-22.
Gonser, S., E. Weber, and G. Folkers. "Peptides and polypeptides as modulators of the immune response: thymopentin—an example with unknown mode of action." Pharmaceutica Acta Helvetiae 73.6 (1999): 265-273.
Wang, Ying, et al. "Synthetic modifications of the immunomodulating peptide thymopentin to confer anti-mycobacterial activity." Biomaterials 35.9 (2014): 3102-3109.

Thymopentin Preparation Products And Raw materials

Raw materials

Preparation Products


Thymopentin Suppliers

Global( 193)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21907 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24196 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20642 58
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2236 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23982 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20094 58

View Lastest Price from Thymopentin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-24 Thymopentin
69558-55-0
US $15.00 / G 1G 99% 20kg career henan chemical co

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