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Osimertinib mesylate

Osimertinib mesylate
Osimertinib mesylate structure
CAS No.
1421373-66-1
Chemical Name:
Osimertinib mesylate
Synonyms
Tagrisso;Osimertinib;Osimertinib d6;AZD-9291 (Mesylate);Mereletinib Ms salt;Mereletinib mesylate;Osimertinib mesylate;Osimertinib methanesulfonate;Osimertinib Mesylate(AZD9291);Osimertinib (AZD9291) mesylate
CBNumber:
CB82677060
Molecular Formula:
C29H37N7O5S
Formula Weight:
595.71298
MOL File:
1421373-66-1.mol

Osimertinib mesylate Properties

SAFETY

HS Code  29339900

Osimertinib mesylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy

Osimertinib mesylate Chemical Properties,Uses,Production

Definition

ChEBI: A methanesulfonate (mesylate) salt prepared from equimolar amounts of osimertinib and methanesulfonic acid. Used for treatment of EGFR T790M mutation positive non-small cell lung cancer.

Indications

The collection of ibrutinib (Imbruvica(R), Pharmacyclics Inc.), afatinib, and osimertinib represents the small, yet expanding, group of covalent SMKIs. Ibrutinib is a non-receptor Bruton’s tyrosine kinase inhibitor approved for the treatment of relapsed chronic lymphocytic leukemia. Afatinib, approved for NSCLC in 2013 and squamous NSCLC in 2016, is a second-generation irreversible EGFR inhibitor that targets wild-type EGFR, the mutant T790M EGFR, and HER2. Osimertinib (AZD9291), which was approved by FDA in November 2015, is a third-generation irreversible EGFR inhibitor that selectively targets the mutant T790M EGFR. Rociletinib, which shares a high degree of structural similarity with that of osimertinib, is a promising covalent EGFR inhibitor developed by Clovis Oncology aimed for the treatment of patients with EGFR T790M-mutated NSCLC, until the company terminated its development in May 2016 following a negative vote fromthe FDA’sOncologic Drugs Advisory Committee.

Osimertinib mesylate Preparation Products And Raw materials

Raw materials

Preparation Products


Osimertinib mesylate Suppliers

Global( 168)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Nanjing Gold Pharmaceutical Technology Co. Ltd.
025-84209270 15906146951
025-84209270 wgp@nanjing-pharmaceutical.com CHINA 117 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 663 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 16534 60
TianYuan Pharmaceutical CO.,LTD
+86-755-23284190 13684996853
+86-755-23284190 sales@tianpharm.com CHINA 308 58
Jinan Shengqi pharmaceutical Co,Ltd
86+15552594168
christine@shengqipharm.com CHINA 339 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58

View Lastest Price from Osimertinib mesylate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-15 AZD-9291 (Mesylate)
1421373-66-1
US $1.00 / KG 1KG 99% 1000KG career henan chemical co
2018-07-19 AZD-9291 (Mesylate)
1421373-66-1
US $10.00 / KG 10G 99% 500kg/month Hebei Chisure Biotechnology Co., Ltd.

1421373-66-1(Osimertinib mesylate)Related Search:


  • Osimertinib d6
  • N-(2-(N-(2-(dimethylamino)ethyl)-N-methylamino)-4-methoxy-5-((4-(1-methyl-1H-indole-3-yl)pyrimidine-2-yl)amino)phenyl)acrylamide methanesulfonate
  • Osimertinib methanesulfonate
  • AZD-9291 mesylate (Osimertinib,Mereletinib)
  • AZD-9291 (Mesylate)
  • N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1)
  • AZD-9291 mesylate N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1)
  • Osimertinib (AZD9291) mesylate
  • Mereletinib mesylate, 98%, a potent and selective mutated forms EGFR inhibitor
  • Osimertinib mesylate
  • Mereletinib mesylate
  • Osimertinib
  • N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt
  • Osimertinib Mesylate(AZD9291)
  • Mereletinib Ms salt
  • AZD9291 Ms salt, Osimertinib Ms salt
  • N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide methanesulfonate
  • N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate
  • Tagrisso
  • 1421373-66-1
  • 421373-66-1
  • -
  • C28H33N7O2CH4O3S
  • C29H37N7O5S
  • AZD09
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