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Azasetron hydrochloride

Azasetron hydrochloride
Azasetron hydrochloride structure
CAS No.
123040-16-4
Chemical Name:
Azasetron hydrochloride
Synonyms
Y-25130;Serotone;AZASETRON;Y-25130HCl;AZASETRON HCL;PubChem CID 2264;Y-25130 HYDROCHLORIDE;Azasetron hydrochloride;INTERMEDIATE OF AZASETRON HCL;Azastron hydrochloride injection
CBNumber:
CB8706748
Molecular Formula:
C17H21Cl2N3O3
Formula Weight:
386.27
MOL File:
123040-16-4.mol

Azasetron hydrochloride Properties

Melting point:
281° (dec); mp 305° (dec) (Kawakita)
storage temp. 
Desiccate at -20°C
CAS DataBase Reference
123040-16-4(CAS DataBase Reference)

SAFETY

Toxicity LD50 in male, female rats (mg/kg): 135, 132 i.v. (Takagi)

Azasetron hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy

Azasetron hydrochloride Chemical Properties,Uses,Production

Description

Nazasetron (azasetron) hydrochloride is the fourth in the class of highly potent 5- HT3 receptor antagonists to reach the market for prophylaxis of severe nausea and vomiting induced by cytotoxic chemotherapy and by total body X-radiation. In a study with 146 cancer patients suffering from emesis induced by cisplatin, nazasetron was reported to be markedly effective in 72% of subjects. Nazasetron is devoid of dopamine D2 receptor blocking activity and therefore is free of the extrapyrimidal side effects associated with other commonly used antiemetics such as metoclopramide and domperidone. Nazasetron has been reported to be potentially useful for the treatment of gastrointestinal motility dysfunction, such as gastric stasis, vomiting and irritable bowel syndrome.

Chemical Properties

White to Off-White Solid

Originator

Yoshitomi (Japan)

Uses

A 5-HT3 receptor antagonist. Used as an antiemetic.

Uses

Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.

brand name

Serotone

Biological Activity

A selective and potent 5-HT 3 antagonist (K i = 2.9 nM).

Azasetron hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Azasetron hydrochloride Suppliers

Global( 107)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15926 69
Zhejiang Jianfeng Haizhou Pharmaceutical Co., Ltd. +86 (576) 88221016,88885932,88891330,88885932
+86 (576) 88811295 sales@haizhoupharm.com China 44 60
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202,021-54308259
+86-21-54291107 info@hanhonggroup.com China 43389 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32492 50
Shanghai civi chemical technology co.,Ltd 86-21-34053660;34053661
86-21-34053661 sale@labgogo.com China 9950 52

View Lastest Price from Azasetron hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-18 Azasetron hydrochloride
123040-16-4
US $7.00 / kg 1kg 99% 100KG career henan chemical co

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