Dopexamine hydrochloride
- CAS No.
- 86484-91-5
- Chemical Name:
- Dopexamine hydrochloride
- Synonyms
- Dopexamine HCl;DOPEXAMINE 2HCL;dopexamine hydrochloride;Dopexamine dihydrochloride CRS;4-(2-((6-(phenethylamino)hexyl)amino)ethyl)benzene-1,2-diol dihydrochloride;4-[2-[[6-[(2-phenylethyl)amino]hexyl]amino]ethyl]-1,2-benzenediol dihydrochloride;1,2-Benzenediol, 4-(2-((6-((2-phenylethyl)amino)hexyl)amino)ethyl)-, dihydrochloride;1,2-Benzenediol,4-[2-[[6-[(2-phenylethyl)amino]hexyl]amino]ethyl]-, hydrochloride (1:2);Beta Receptor,Adrenergic Receptor,Dopexamine,Inhibitor,Dopexamine hydrochloride,inhibit
- CBNumber:
- CB8854940
- Molecular Formula:
- C22H34Cl2N2O2
- Molecular Weight:
- 429.42356
- MDL Number:
- MFCD00887597
- MOL File:
- 86484-91-5.mol
- MSDS File:
- SDS
| Melting point | 213-215°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | Soluble in water, sparingly soluble in ethanol (96 per cent) and in methanol, practically insoluble in acetone. |
| color | White to Light Grey |
| Stability | Hygroscopic |
| EWG's Food Scores | 1 |
| FDA UNII | 0VN909S60Y |
Dopexamine hydrochloride price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000612 | Dopexamine dihydrochloride European Pharmacopoeia (EP) Reference Standard | 86484-91-5 | y0000612 | $220 | 2024-03-01 | Buy |
| Usbiological | 010950 | Dopexamine Hydrochloride | 86484-91-5 | 10mg | $446 | 2021-12-16 | Buy |
| TRC | D533900 | DopexamineHydrochloride | 86484-91-5 | 50mg | $1060 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 45948 | DopexamineHCl | 86484-91-5 | 100mg | $2120 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0025149 | DOPEXAMINE DIHYDROCHLORIDE 95.00% | 86484-91-5 | 5MG | $504.66 | 2021-12-16 | Buy |
Dopexamine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
Dopexamine is a synthetic dopamine analog and acts as a a β2-adrenergic receptor agonistt as well as an agonist at peripheral dopamine receptors. Dopexamine hydrochloride has been used to improve myocardial and renal performance in patients suffering from low cardiac output states.
Uses
Dopexamine is a synthetic dopamine analog and acts as a a β2-adrenergic receptor agonistt as well as an agonist at peripheral dopamine receptors. Dopexamine has been used to improve myocardial and renal performance in patients suffering from low cardiac output states.
brand name
Dopacard (Fisons).
Clinical Use
Inotropic support in exacerbations of heart failure and heart failure associated with cardiac surgery
Drug interactions
Potentially hazardous interactions with other drugs
Anaesthetics: risk of ventricular arrhythmias with
isoflurane - avoid.
Antidepressants: risk of hypertensive crisis with
MAOIs and moclobemide.
Beta-blockers: risk of severe hypertension
Dopaminergics: avoid with rasagiline.
Sympathomimetics: effects of adrennoradrenaline possibly enhanced.
Metabolism
Dopexamine is rapidly eliminated from blood with a halflife of approximately 6-7 minutes in healthy volunteers and around 11 minutes in patients with cardiac failure. Subsequent elimination of the metabolites is by urinary and biliary excretion.
Dopexamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15396 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52861 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Longsheng chemical Co.,Ltd. | 021-58099652-8005 13585536065 | bin.wu@shlschem.com | China | 9816 | 59 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3427 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17993 | 56 |