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Avanafil

Avanafil
Avanafil structure
CAS No.
330784-47-9
Chemical Name:
Avanafil
Synonyms
D03217;avanfil;vanafil;Stendra;Avanafil;Avanafil-d3;Avanafil(TA-1790);Avanafil (usan/inn);Avanafil PDE5 inhibitor;Natural Sex Steroid Hormones Avanafil Hormone Powder C23H26ClN7O3 CAS 330784-47-9
CBNumber:
CB91503998
Molecular Formula:
C23H26ClN7O3
Formula Weight:
483.95
MOL File:
330784-47-9.mol

Avanafil Properties

Melting point:
150-152°C
Density 
1.372
storage temp. 
Refrigerator
pka
11.84±0.46(Predicted)
CAS DataBase Reference
330784-47-9(CAS DataBase Reference)
FDA UNII
DR5S136IVO
SAFETY
  • Risk and Safety Statements
HS Code  29339900

Avanafil price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23024 Avanafil ≥98% 330784-47-9 100mg $25 2020-06-24 Buy
Cayman Chemical 23024 Avanafil ≥98% 330784-47-9 250mg $56 2020-06-24 Buy
Cayman Chemical 23024 Avanafil ≥98% 330784-47-9 500mg $94 2020-06-24 Buy
Cayman Chemical 23024 Avanafil ≥98% 330784-47-9 1g $163 2020-06-24 Buy

Avanafil Chemical Properties,Uses,Production

Description

Avanafil (Zepeed) was approved by the Korean Health Ministry for the treatment of erectile dysfunction (ED) in August 2011. Avanafil is a highly selective type 5 phosphodiesterase (PDE5) inhibitor. Avanafil is reported to be the most selective PDE5 inhibitor on the market. The onset of Tmax and half-life also varies among the marketed PDE5 inhibitors. Sildenafil has a Tmax at 1 h and a half-life of 3–5 h. Vardenafil is somewhat similar with a Tmax of 0.6 h and a half-life of 4–6 h. Tadalafil has the longest half-life among the marketed drugs with a half-life of 17 h. Avanafil has a fast onset of action reaching Tmax in 0.6 h with a half-life of 1.2 h. A synthesis of avanafil (TA-1790) is described in the patent literature. The main elimination route of avanafil is through the bile and feces. Avanafil was also found to be reabsorbed through enterohepatic recirculation.

Chemical Properties

White Solid

Originator

Mitsubishi Tanabe Pharma Corporation (Japan)

Uses

Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM.

Uses

A phosphodiesterase

Definition

ChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid with the amino group of pyrimidin-2-ylmethylamine Used for treatment of erectile dysfunction.

brand name

Zepeed

Avanafil Preparation Products And Raw materials

Raw materials

Preparation Products


Avanafil Suppliers

Global( 240)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 568 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 739 60
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1817 55
Hebei Huanhao Biotechnology Co., Ltd.
+8618034552304
86-0311-83975816 cathylee@hbhuanhao.com CHINA 865 58
hdzhl biotechnology co., ltd
86-13032617415
sales@luchibiology.com CHINA 1277 58
Shanghai Payne Pharmaceutical Technology Co.Ltd
18678586262 021-58123769
info@paynepharm.com China 1355 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3014 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24754 60

View Lastest Price from Avanafil manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-03 Avanafil
330784-47-9
US $10.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
2019-12-30 Avanafil
330784-47-9
US $0.00-0.00 / KG 5mg 99% HPLC 2000tons Shaanxi Dideu Medichem Co. Ltd
2019-10-21 avanafil
330784-47-9
US $60.00 / KG 1g 99.8% 10tons Hebei shuoxi biotechnology co. LTD

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