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Bacitracin

Bacitracin
Bacitracin
CAS No.
1405-87-4
Chemical Name:
Bacitracin
Synonyms
septa;ayfivin;Agfivin;baci-jel;usafcb-7;BACIDRIN;ALTRACIN;Zutracin;Baciguen;baciguent
CBNumber:
CB9165863
Molecular Formula:
C66H102N17O16S
Formula Weight:
1421.68538
MOL File:
1405-87-4.mol

Bacitracin Properties

Melting point:
221-225°C
Density 
1.0166 (rough estimate)
refractive index 
1.6700 (estimate)
storage temp. 
2-8°C
solubility 
H2O: 50 mg/mL, clear to very slightly hazy, deep yellow
form 
Powder
color 
white to faintly beige
Water Solubility 
soluble
Merck 
13,936
EPA Substance Registry System
Bacitracin(1405-87-4)

SAFETY

Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  22-24/25-45-36
WGK Germany  2
RTECS  CP0175000
21
TSCA  Yes
Hazardous Substances Data 1405-87-4(Hazardous Substances Data)

Bacitracin price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 11702 Bacitracin from 1405-87-4 5g $73.6 2018-11-20 Buy
Sigma-Aldrich 11702 Bacitracin from 1405-87-4 25g $272 2018-11-20 Buy
Alfa Aesar J62432 Bacitracin 1405-87-4 25g $142 2018-11-13 Buy
Alfa Aesar J62432 Bacitracin 1405-87-4 5g $54.3 2018-11-13 Buy
Sigma-Aldrich 1951-M Bacitracin 1405-87-4 250ku $55.6 2018-11-20 Buy

Bacitracin Chemical Properties,Uses,Production

Chemical Properties

White to pale buff powder

Chemical Properties

Bacitracin is a white to light tan powder which is odorless or having a slight odor and very bitter taste.

Uses

Polypeptide antibacterial.

Uses

Bacitracin is a peptide antibiotic effective against gram-postive bacteria. Bacitracin is an inhibitor of peptidoglycan synthesis. Bacitracin disrupts bacterial cell wall synthesis by inhibiting depho sphorylation of lipid pyrophosphate. Bacitracin also strongly inhibits proline endopeptidase from human muscle.

Definition

A complex of cyclic peptide antibiotic of known chemical structure isolated from the Tracy-I strain of Bacillus subtilis.

brand name

Ziba (X Gen).

Hazard

Poison; moderately toxic; mutagen.

Safety Profile

A poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Mutation data reported.

Potential Exposure

Bacitracin is used as an ingredient in antibiotic ointments to treat or prevent topical or eye infections. Commercial Bacitracin is a mixture of at least 9 bacitracins. Also used as a feed and drinking water additive for animals; as a food additive for human consumption.

First aid

In case of large-scale exposure, the directions for medicines (nonspecific, n.o.s.) would be applied as follows: Move victim to fresh air; call emergency medical care. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In case of contact with material, immediately flush skin or eyes with running water for at least 15 minutes. Speed in removing material from skin is of extreme importance. Remove and isolate contaminated clothing and shoes at the site. Keep victim quiet and maintain normal body temperature. Effects may be delayed; keep victim under observation.

Shipping

UN 3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1—Poisonous materials.

Purification Methods

Bacitracin has been purified by carrier displacement using n-heptanol, n-octanol and n-nonanol as carriers and 50% EtOH in 0.1 N HCl. The pure material gives one spot with RF ~0.5 on paper chromatography using AcOH:n-BuOH:H2O (4:1:5). [Porath Acta Chem Scand 6 1237 1952.] It has also been purified by ion-exchange chromatography. It is a white powder soluble in H2O and EtOH but insoluble in Et2O, CHCl3 and Me2CO. It is stable in acidic solution but unstable in base. It is a strong antibacterial. [Abraham & Bewton Biochem J 47 257 1950, Synthesis: Munekata et al. Bull Chem Soc Jpn 46 3187, 3835 1973, Beilstein 27 III/IV 5746.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

Waste Disposal

It is inappropriate and possibly dangerous to the environment to dispose of expired or waste pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.

Bacitracin Preparation Products And Raw materials

Raw materials

Preparation Products


Bacitracin Suppliers

Global( 182)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22063 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20795 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32764 55
Anhui Royal Chemical Co., Ltd.
+86-025-86736275
dana.jiang@royal-chem.com CHINA 790 55
Kono Chem Co., Ltd
+86-132 8924 6953
info@konochemical.com CHINA 2164 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20001 58
Nantong Wanrong International Trading Co., Ltd. 86-(0)513-85202682;86-(0)513-85902659;86-(0)18915758723
86-(0)513-85202682 stdinochem@gmail.com;yuhua-921@163.com China 99 58
Kono Chem Co.,Ltd 029-86107037-8012
029-86107037 info@konochemical.com China 2380 55
Xi'an boliante Chemical Co., Ltd. 17719597442
- 3570451756@qq.com China 3257 58
AiBoShi medicine shijiazhuang science and technology co., LTD 0311-68036371;86905286,15830127659
0311-89897608 info@apexpharmatech.com China 41 58

View Lastest Price from Bacitracin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Bacitracin
1405-87-4
US $1.00 / KG 1G 98% 100KG career henan chemical co

Bacitracin Spectrum


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