Acridine
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Acridine Properties
- Melting point:
- 106-109 °C
- Boiling point:
- 346 °C(lit.)
- Density
- 1,005 g/cm3
- refractive index
- 1.7270 (estimate)
- Flash point:
- 346°C
- storage temp.
- Refrigerator
- solubility
- dioxane: 0.1 g/mL, clear
- pka
- 5.58(at 20℃)
- form
- Crystalline Powder
- color
- Yellow to yellow-brown
- PH Range
- Green B uorescence (5.2) to violet B uorescence (6.6)
- λmax
- 358nm, 392nm
- Merck
- 14,122
- BRN
- 120200
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- Major Application
- Organic light-emitting diode, photoresists, nanosensors, fuel cells, memory device, semiconductors, information storage device, liquid crystal displays, identification of product forgeries, inks, adhesives, textile, hair dyes, gene detection assay, staining cells, biosensors, detecting nucleic acids, proteins, antiHCV antibodies, antibacterial, antiamyloid agents, wound dressing materials, vaccines against infection, allergy and cancer
- CAS DataBase Reference
- 260-94-6(CAS DataBase Reference)
SAFETY
- Risk and Safety Statements
- Hazard and Precautionary Statements (GHS)
Hazard Codes | Xn | ||
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Risk Statements | 22-68-36/37/38 | ||
Safety Statements | 22-36-45-36/37/39-26 | ||
RIDADR | UN 2713 6.1/PG 3 |
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WGK Germany | 3 |
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RTECS | AR7175000 |
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TSCA | Yes | ||
HazardClass | 6.1 | ||
PackingGroup | III | ||
Toxicity | LD50 s.c. in mice: 0.40 g/kg (Rubbo) |
Symbol(GHS): |
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Acridine price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 01640 | Acridine BioReagent, suitable for fluorescence, ≥97.0% (HPLC) | 260-94-6 | 1g | $37 | 2018-11-22 | Buy |
Sigma-Aldrich | 01640 | Acridine BioReagent, suitable for fluorescence, ≥97.0% (HPLC) | 260-94-6 | 10g | $87.5 | 2018-11-22 | Buy |
TCI Chemical | A0129 | Acridine Zone Refined (number of passes:45) >99.0%(HPLC)(T) | 260-94-6 | 1sample | $230 | 2018-11-22 | Buy |
TCI Chemical | A0294 | Acridine >98.0%(HPLC)(T) | 260-94-6 | 5g | $91 | 2018-11-22 | Buy |
Alfa Aesar | L01657 | Acridine, 97% | 260-94-6 | 5g | $46.4 | 2018-11-13 | Buy |
Acridine Chemical Properties,Uses,Production
Chemical Properties
colourless to light yellow crystalsUses
A quinoline derivative used as manufacturing dyes and as intermediate for antileishmanial agents. A catabolic product of carbamazepine (C175840) metabolite.Definition
ChEBI: A polycyclic heteroarene that is anthracene in which one of the central CH groups is replaced by a nitrogen atom.Uses
manufacture of dyes and intermediates; some dyes derived from it are used as antiseptics, e.g. 9-aminoacridine, acriflavine and proflavine. The hydrochloride has been used as reagent for cobalt, iron and zinc.General Description
Small colorless needle-like crystalline solid. Slightly soluble in hot water. Slightly denser than water. Contact may irritate skin, eyes, and mucous membranes. Sublimes before melting when heated. May be toxic by ingestion.Air & Water Reactions
Slightly soluble in hot water.Reactivity Profile
Acridine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. Burns to give toxic oxides of nitrogen.Health Hazard
Inhalation irritates respiratory system and causes sneezing, crying, and vomiting. Contact with liquid irritates eyes, skin, and mucous membranes. At high temperature and during sun exposure, damage to the cornea, skin, and mucous membranes may occur following the liberation of Acridine vapor.Safety Profile
Poison by ingestion, subcutaneous, and intravenous routes. Mutation data reported. A skin, eye, and mucous membrane irritant. When heated to decomposition it emits toxic fumes of NO,.Potential Exposure
Acridine and its derivatives are widely used in the production of dyestuffs, such as acriflavine, benzoflavine, and chrysaniline; and in the synthesis of pharmaceuticals; such as aurinacrine, proflavine, and rivanol. A constituent of coal tar, coal tar creosote; found in wastes from gas and tar plants and coke oven emissions. Incompatibilities: Strong acids, strong oxidizers.First aid
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. If this chemical has been inhaled, remove from exposure and transfer promptly to a medical facility.Shipping
UN2713 Acridine, Hazard Class: 6.1; Labels: 6.1-Poisonous materialsPurification Methods
Acridine has been crystallised twice from *benzene/cyclohexane, or from aqueous EtOH, then sublimed, removing and discarding the first 25% of the sublimate. The remainder is again crystallised and sublimed, discarding the first 10-15% [Wolf & Anderson J Am Chem Soc 77 1608 1955]. Acridine can also be purified by crystallisation from n-heptane and then from ethanol/water after pre-treatment with activated charcoal, or by chromatography on alumina with pet ether in a darkened room. Alternatively, acridine can be precipitated as the hydrochloride from *benzene solution by adding HCl, after which the base is regenerated, dried at 110o/50mm, and recrystallised to constant melting point from pet ether [Cumper et al. J Chem Soc 4518 1962]. The regenerated free base may be recrystallised, chromatographed on basic alumina, then vacuum-sublimed and zone-refined. [Williams & Clarke, J Chem Soc, Faraday Trans 1 73 514 1977, Albert, The Acridines Arnold Press 1966.] It can exist in five crystalline forms and is steam volatile. It is a strong IRRITANT to skin and mucous membranes and can become a chronic irritant— handle it with CARE. [Beilstein 20/8 V 199.]Incompatibilities
Acridine and its derivatives are widely used in the production of dyestuffs, such as acriflavine, benzoflavine, and chrysaniline; and in the synthesis of pharmaceuticals; such as aurinacrine, proflavine, and rivanol. A constituent of coal tar, coal tar creosote; found in wastes from gas and tar plants and coke oven emissions. Incompatibilities: Strong acids, strong oxidizers.Waste Disposal
Incineration with nitrogen oxide removal from the effluent gas by scrubber, catalytic, or thermal device.Acridine Preparation Products And Raw materials
Raw materials
Preparation Products
Acridine Suppliers
Global( 130)Suppliers
Supplier | Tel | Fax | Country | ProdList | Advantage | |
---|---|---|---|---|---|---|
Zhengzhou Yuanli Biological Technology Co., Ltd | 0086-371-67897895 |
info@zzyuanli.cn | CHINA | 121 | 58 | |
Mainchem Co., Ltd. | +86-0592-6210733 |
+86-0592-6210733 | sales@mainchem.com | CHINA | 32764 | 55 |
career henan chemical co | +86-371-86658258 |
sales@coreychem.com | CHINA | 20001 | 58 | |
Henan Wanxiang Chemical Industry Co., Ltd. | 0371-56669001、56669008 |
0371-56669008 | 58chem@163.com | China | 84 | 62 |
PeiShen biological engineering (Shanghai) co., LTD | 021-33040955-0;13651980230 |
021-61330236 | pszsy@pssh.com.cn | China | 116 | 58 |
SiChuang NanBu Honesty Technology Co., Ltd. | 0838-5675166 |
0838-5675535 | nbcxkj@126.com | China | 701 | 55 |
J & K SCIENTIFIC LTD. | 400-666-7788 +86-10-82848833 |
+86-10-82849933 | jkinfo@jkchemical.com;market6@jkchemical.com | China | 96815 | 76 |
Meryer (Shanghai) Chemical Technology Co., Ltd. | +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing) |
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) | sh@meryer.com | China | 40399 | 62 |
Alfa Aesar | 400-610-6006; 021-67582000 |
021-67582001/03/05 | saleschina@alfa-asia.com | China | 30308 | 84 |
TCI (Shanghai) Development Co., Ltd. | 021-67121386 / 800-988-0390 |
021-67121385 | Sales-CN@TCIchemicals.com | China | 24654 | 81 |
View Lastest Price from Acridine manufacturers
Image | Release date | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2018-08-12 |
Acridine 260-94-6 |
US $1.00 / KG | 1G | 99% | 100kg | career henan chemical co |
260-94-6(Acridine)Related Search:
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- DIBENZO[B,E]PYRIDINE
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