Pregabalin (Lyrica), a derivative of GABA that is closely related to gabapentin, has undergone extensive research for its efficacy in treating conditions such as generalized anxiety disorder (GAD), fibromyalgia, neuropathic pain, and partial complex seizures. It seems to have a more targeted effect on the a2-δ subunit of calcium channels in the brain compared to gabapentin. Pregabalin was granted FDA approval at the end of 2004 for the treatment of neuropathic pain and epilepsy. In 2008, it became the first medication approved for the management of fibromyalgia. Although pregabalin was approved for GAD treatment in the European Union in 2006, it has not yet received FDA approval for GAD in the United States as of the time of writing.
화학적 성질
Off-White Solid
용도
S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
일반 설명
Pregabalin, marketed as the anticonvulsant drug Lyrica, is used in the treatment of epilepsy and generalized anxiety disorder. Along with other anticonvulsants such as gabapentin and levetiracetam, pregabalin is also used to treat neuropathic pain. This certified reference standard is suitable for pregabalin GC/MS or LC/MS applications from forensic analysis, clinical toxicology and pain prescription monitoring to urine drug testing.
