parsalmide

parsalmide 구조식 이미지
카스 번호:
30653-83-9
상품명:
parsalmide
동의어(영문):
Parsal;MY-41-6;parsalmide;5-Amino-N-butyl-2-(2-propynyloxy)benzamide;5-Amino-N-butyl-2-(2-propyn-1-yloxy)benzamide;Benzamide, 5-amino-N-butyl-2-(2-propyn-1-yloxy)-
CBNumber:
CB2882635
분자식:
C14H18N2O2
포뮬러 무게:
246.3
MOL 파일:
30653-83-9.mol

parsalmide 속성

녹는점
83-85℃
끓는 점
389.31°C (rough estimate)
밀도
1.107
굴절률
1.5500 (estimate)
산도 계수 (pKa)
pKa (aq soln, 20°) 4.6 ±0.03

안전

parsalmide C화학적 특성, 용도, 생산

Originator

Parsalmide,Shanghai Lansheng Corporation

Manufacturing Process

5-Acetylamino-2-acetoxybenzoyl chloride was obtained by reaction of 5acetylamino-2-acetoxy-benzoic acid with thionylchloride.
5-Acetylamino-N-butyl-2-hydroxybenzamide was produced in the result of treatment of 5-acetylamino-2-acetoxybenzoyl chloride with butylamine in the presence of sodium hydroxide
5-Acetamino-N-(n-butyl)-2-propargyloxybenzamide was obtained by reaction of 5-acetylamino-N-butyl-2-hydroxybenzamide with propargylbromide in the presence of sodium, isopropyl alcohol and sulfuric acid.
28.8 g (0.1 mole) 5-acetamino-N-(n-butyl)-2-propargyloxybenzamide in 320 ml of 4 N sulfuric acid was heated, under stirring, at 90°-95°C for 2 h. The clear solution was cooled and its pH adjusted to 1 with 1 N NaOH; after filtering, further alkali was subsequently added until a pH of 10 was obtained. At this point the product was separated by filtration and recrystallized from ethanol at 60°C to give 16.6 g (a yield of 68%) of chromatographically pure 5-amino-N-(n-hutyl)-2-propargyloxybenzamide; melting point 85°-87°C.

Therapeutic Function

Muscle relaxant, Antiinflammatory, Analgesic

parsalmide 준비 용품 및 원자재

원자재

준비 용품


parsalmide 공급 업체

글로벌( 5)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Shaanxi Didu New Material Co., Ltd 029-63373950 15353716720
1052@dideu.com China 10004 58

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