ChemicalBook
Chinese English Japanese Germany Korea

아프로틴

아프로틴
아프로틴 구조식 이미지
카스 번호:
9087-70-1
한글명:
아프로틴
동의어(한글):
아프로틴;아프로틴(APROTININ)
상품명:
Aprotinin
동의어(영문):
BPTI;fosten;rp-9921;TRASYLOL;onquinin;repulson;riker52g;trazinin;zymofren;antilysin
CBNumber:
CB3329436
분자식:
C284H432N84O78R2S7
포뮬러 무게:
6495.43988
MOL 파일:
9087-70-1.mol

아프로틴 속성

저장 조건
2-8°C
용해도
glycerol: soluble3mg/mL, clear, colorless (equilibration buffer containing 5% glycerol)
물리적 상태
lyophilized powder
색상
white
수용성
Freely soluble in water and in aqueous buffers of low ionic strength.
Merck
13,761
안정성
Stable. Incompatible with strong oxidizing agents.

안전

위험품 표기 Xn,Xi
위험 카페고리 넘버 42/43-36/37/38-20/21/22
안전지침서 22-45-36/37-36-26
WGK 독일 1
RTECS 번호 YN5080000
F 고인화성물질 10-21
HS 번호 35040000
유해 물질 데이터 9087-70-1(Hazardous Substances Data)
독성 LD50 i.v. in mice: 2500000 kallikrein inhibitor units/kg (Trautschold)
기존화학 물질 KE-34949

아프로틴 MSDS


Aprotinin

아프로틴 C화학적 특성, 용도, 생산

화학적 성질

white powder

Originator

Trasylol,Bayer

용도

Aprotinin is largely used as an inhibitor of trypsin.

용도

Proteolytic inhibitor in radioimmunoassays of polypeptide hormones.

Manufacturing Process

1 kg of parotid of cattle, which were freed of fat and flesh are comminuted in a meat chopper and twice extracted with 5 L of acetone. The acetone was removed as far as possible by sucking off and the moist material is digested for 2.5 hours in 1.2 L of 1 N acetic acid and 2.8 L of 96% ethanol at 50°C. The filtrate containts about 230.000 inactivator units.
The alcoholic solution is concentrated to 1.2 L by evaporating in vacuo and shaken with an equal amount of ether. Dark coloring matters and residues of fat are thus dissolved. The aqueous phase is now mixed with acetone until a precipitate occurs and the dissolved in dilute acetic acid. The solution is brought to a weakly alkaline pH by addition of ammonia. It is then centrifuged and the inactivator is precipitated with five times the amount of ethanol. The yield amounts to about 180.000 kallikrein inactivator units in 0.4-0.5 g of substance.

상표명

Trasylol (Bayer).

Therapeutic Function

Proteinase inhibitor

Safety Profile

Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.

아프로틴 준비 용품 및 원자재

원자재

준비 용품


아프로틴 공급 업체

글로벌( 251)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21031 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 3001 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29960 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19753 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu zzwenxi@126.com CHINA 13187 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17607 58

Copyright 2019 © ChemicalBook. All rights reserved