Chinese English Japanese Germany Korea

트리클로르아세트 산

트리클로르아세트 산
트리클로르아세트 산 구조식 이미지
카스 번호:
트리클로르아세트 산
Trichloroacetic acid
TCA;nata;TKhU;TkhV;NA TA;natal;TKhUK;TkhVk;500ml;tecane
포뮬러 무게:
MOL 파일:

트리클로르아세트 산 속성

54-58 °C (lit.)
끓는 점
196 °C (lit.)
1.62 g/mL at 25 °C (lit.)
증기 밀도
<1 (vs air)
1 mm Hg ( 51 °C)
n20/D 1.62(lit.)
저장 조건
Store at +15°C to +25°C.
H2O: 0.5 M at 20 °C, clear, colorless
산도 계수 (pKa)
0.7(at 25℃)
물리적 상태
<1.0 (25℃, 0.5M in H2O)
120 g/100 mL (20 ºC)
최대 파장(λmax)
Stable, but moisture sensitive. Incompatible with water, strong bases. Note that the Merck Index states that this material is hydrolytically unstable in aqueous solution below 30% by weight. Decomposition products include carbon monoxide and carbon dioxide. The generation of these gases in a sealed container may lead to a pressure rise sufficien
CAS 데이터베이스
76-03-9(CAS DataBase Reference)
2B (Vol. 63, 84, 106) 2014
Acetic acid, trichloro-(76-03-9)
Trichloroacetic acid (76-03-9)
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,N,C,F,Xi
위험 카페고리 넘버 36/37/38-40-51/53-50/53-35-38-11-34-67-52/53
안전지침서 26-36/37-61-60-45-36/37/39-24/25-16
유엔번호(UN No.) UN 1839 8/PG 2
WGK 독일 2
RTECS 번호 AJ7875000
F 고인화성물질 10-21
자연 발화 온도 711 °C
위험 참고 사항 Corrosive/Hygroscopic
위험 등급 8
포장분류 II
HS 번호 29154000
유해 물질 데이터 76-03-9(Hazardous Substances Data)
독성 LD50 orally in rats: 5000 mg/kg (Bailey, White)
기존화학 물질 KE-34058
유해화학물질 필터링 97-1-308
함량 및 규제정보 물질구분: 유독물질; 혼합물(제품)함량정보: 트리클로로아세트산 및 이를 25% 이상 함유한 혼합물
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H225 고인화성 액체 및 증기 인화성 액체 구분 2 위험 P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H314 피부에 심한 화상과 눈에 손상을 일으킴 피부부식성 또는 자극성물질 구분 1A, B, C 위험 P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 P264, P280, P302+P352, P321,P332+P313, P362
H318 눈에 심한 손상을 일으킴 심한 눈 손상 또는 자극성 물질 구분 1 위험 P280, P305+P351+P338, P310
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고
H336 졸음 또는 현기증을 일으킬 수 있음 특정표적장기 독성 물질(1회 노출);마취작용 구분 3 경고 P261, P271, P304+P340, P312,P403+P233, P405, P501
H351 암을 일으킬 것으로 의심됨 (노출되어도 암을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재) 발암성 물질 구분 2 경고 P201, P202, P281, P308+P313, P405,P501
H373 장기간 또는 반복 노출되면 장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킬 수 있음 특정 표적장기 독성 - 반복 노출 구분 2 경고 P260, P314, P501
H400 수생생물에 매우 유독함 수생 환경유해성 물질 - 급성 구분 1 경고 P273, P391, P501
H401 수생생물에 유독함 수생 환경유해성 물질 - 급성 구분 2 P273, P501
H410 장기적 영향에 의해 수생생물에 매우 유독함 수생 환경유해성 물질 - 만성 구분 1 경고 P273, P391, P501
H411 장기적 영향에 의해 수생생물에 유독함 수생 환경유해성 물질 - 만성 구분 2
H412 장기적 영향에 의해 수생생물에 유해함 수생 환경유해성 물질 - 만성 구분 3 P273, P501
P210 열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P391 누출물을 모으시오.
P301+P330+P331 삼켰다면 입을 씻어내시오. 토하게 하려 하지 마시오.
P303+P361+P353 피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P370+P378 화재 시 불을 끄기 위해 (Section 5. 폭발, 화재시 대처방법의 적절한 소화제)을(를) 사용하시오.
P405 밀봉하여 저장하시오.
P403+P235 환기가 잘 되는 곳에 보관하고 저온으로 유지하시오.
P501 ...에 내용물 / 용기를 폐기 하시오.
NFPA 704
3 0

트리클로르아세트 산 MSDS


트리클로르아세트 산 C화학적 특성, 용도, 생산

화학적 성질

Trichloroacetic acid, is a colorless crystalline solid. Trichloroacetic acid absorbs moisture from air and forms a syrup. Trichloroacetic acid is soluble in water with release of heat. Trichloroacetic acid is corrosive to metals and tissue.

화학적 성질

Trichloroacetic acid is a colorless crystalline solid which is used in liquid solutions.


As a reagent for albumin detection; in making herbicides. It is found as a by-product after chlorination of water containing humic materials.


Protein precipitation reagentTrichloroacetic acid is used as a precipitating agent in biochemistry for precipitation of proteins, DNA and RNA. It is an active ingredient used in cosmetic treatments like chemical peels, tattoo removal and the treatment of warts including genital warts. It is also used to determine protein concentration and as a decalcifier and fixative in microscopy.


Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative, as a laboratory reagent, a herbicide, in medicine, and in microscopy.


Trichloroacetate (TCA) is used primarily for the selective control of annual and perennial grass weeds in cropland and noncropland. TCA is acidic in nature and are not strongly sorbed by soils. It is reported to be rapidly degraded in both soil and water by microbial processes. However, the breakdown of TCA occurs very slowly when incubated at 14–15 °C in acidic soils. iming not only accelerates this degradation but also increases the numbers of TCA-degrading bacteria.


ChEBI: A monocarboxylic acid that is acetic acid in which all three methyl hydrogens are substituted by chlorine.

일반 설명

Trichloroacetic acid (TCA) is derived from Trichloroethylene (TCE) metabolism. It is used as an acid decalcifying agent. TCA is used as a fixative for nuclear staining and protein precipitation.

반응 프로필

Trichloroacetic acid is a strong acid; when heated, in the presence of water, decomposes forming phosgene and HCl. [Handling Chemicals Safely 1980 p. 915]. The acid was added to copper wool and rinsed down with dimethyl sulfoxide. This caused what was thought to be an extremely exothermic dehydrohalogenation reaction that melted the neck of the flask, [Chem. Eng. News, 1981, 59(28), 4].


TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.


Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Biochem/physiol Actions

TCA might act as a carcinogen, targeting liver. It might be used as an acid decalcifying agent. TCA helps in nuclear staining.

Safety Profile

Poison by ingestion and subcutaneous routes. Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental carcinogenic data. Experimental reproductive effects. Mutation data reported. A corrosive irritant to skin, eyes, and mucous membranes. When heated to decomposition it emits toxic fumes of Cland Na2O. Used as an herbicide.

잠재적 노출

This haloacetic acid can be a byproduct of drinking water disinfection and may increase the risk of cancer. Trichloroacetic acid is used as medication; in organic syntheses; as a reagent for albumin detection; as an intermediate in pesticide manufacture and in the production of sodium trichloroacetate which is itself a herbicide.


TCA was not mutagenic in bacterial assays.The IARC has determined that there is limited evidence for the carcinogenicity of TCA in experimental animals and that it is not classifiable as to its carcinogenicity to humans. Neutralized TCA was not clastogenic in human lymphocytes in vitro or in the mouse bone marrow micronucleus test.

운송 방법

UN1839 (solid) & UN2564 (solution) Trichloroacetic acid, solid and Trichloroacetic acid, solution, Hazard class: 8; Labels: 8-Corrosive material.

Purification Methods

Purify the acid by fractional crystallisation from its melt, then crystallise it repeatedly from dry *benzene and store it over conc H2SO4 in a vacuum desiccator. It can also be crystallised from CHCl3 or cyclohexane, and dried over P2O5 or Mg(ClO4)2 in a vacuum desiccator. Trichloroacetic acid can be fractionally distilled under reduced pressure from MgSO4. Layne, Jaffé and Zimmer [J Am Chem Soc 85 435 1963] dried trichloroacetic acid in *benzene by distilling off the *benzene-water azeotrope, then crystallised the acid from the remaining *benzene solution. Manipulations should be carried out under N2. [Toxic vapours, use a well ventilated fume cupboard.] [Beilstein 2 IV 508.]

비 호환성

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, silver salts, strong acids, strong bases, moisture, iron, zinc, aluminum. Corrosive to iron, steel and other metals.

참고 문헌

트리클로르아세트 산 준비 용품 및 원자재


준비 용품

트리클로르아세트 산 공급 업체

글로벌( 321)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 China 5942 58
Shanghai Time Chemicals CO., Ltd.
+8618017249410 +86-021-57951555
+86-021-57951555 China 1807 55
Hangzhou FandaChem Co.,Ltd.
+86-571-56059825 CHINA 9150 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418697 China 3000 55
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967 CHINA 1011 58
+86 18953170293
+86 0531-67809011 CHINA 2940 58
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28229 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114 CHINA 6369 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23035 58
Shandong chuangyingchemical Co., Ltd.
18853181302 CHINA 5917 58

트리클로르아세트 산 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved