라피노오스

라피노오스
라피노오스 구조식 이미지
카스 번호:
512-69-6
한글명:
라피노오스
동의어(한글):
라피노오스
상품명:
Raffinose
동의어(영문):
D-RAFFINOSE;melitriose;Cottonseed oligosaccharides;ffinose;NSC 2025;NSC26414;RAFFINOSE;gossypose;NSC-26414;NSC 26414
CBNumber:
CB5290712
분자식:
C18H32O16
포뮬러 무게:
504.44
MOL 파일:
512-69-6.mol
MSDS 파일:
SDS

라피노오스 속성

녹는점
81℃
끓는 점
513.84°C (rough estimate)
밀도
1.81
굴절률
1.6760 (estimate)
저장 조건
2-8°C
용해도
|DMSO : 100 mg/mL (198.24 mM; Need ultrasonic)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
pK1:12.74 (25°C)
색상
흰색에서 황백색까지
수용성
229.8g/L(25℃)
안정성
안정적인. 강한 산화제와 호환되지 않습니다. 타기 쉬운.
LogP
-5.104 (est)
CAS 데이터베이스
512-69-6(CAS DataBase Reference)
EPA
.alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl O-.alpha.-D-galactopyranosyl-(1.fwdarw.6)- (512-69-6)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
안전지침서 24/25
HS 번호 29389090
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
예방조치문구:
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P270 이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.

라피노오스 C화학적 특성, 용도, 생산

화학적 성질

Raffinose is a white crystalline powder. It is odorless and has a sweet taste approximately 10% that of sucrose.

용도

D-(+)-Raffinose is an oligosaccharide and trisaccharide whose physical structure and chemical properties have been shown to affect the stability and crystallization of amorphous sucrose, helping to increase the shelf-life of sucrose-containing foods.

생산 방법

Raffinose occurs naturally in Australian manna, cottonseed meal, and seeds of various food legumes. It can be isolated from beet sugar molasses through sucrose separation, seed-crystallization, and filtration.

Pharmaceutical Applications

Raffinose is a trisaccharide carbohydrate that is used as a bulking agent, blood substitute, stabilizing agent, and water scavenger in freeze-drying where it acts as a stabilizer for freeze-dried formulations. It is also used as a crystallization inhibitor in sucrose solutions.

Safety

Raffinose is a naturally occurring trisaccharide investigated for use in freeze-dried pharmaceutical formulations. It occurs in a number of plants that are consumed widely.

저장

Raffinose is stable under ordinary conditions of use and storage. Excessive heat should be avoided to prevent degradation. Thermal decomposition products are carbon monoxide and carbon dioxide.

Purification Methods

fructo-furanose [17629-30-0 (5H2O), 512-69-6 (anhydrous)] M 594.5, m 8 0o, 80 -82o, +124o (c 10, H2O), [ ] D +105o (c 1 for pentahydrate, H2O), pK 1 12.40, pK 2 13.44, pK 3 13.52. D(+)-Raffinose crystallises from H2O, 90% aqueous EtOH or MeOH as the pentahydrate. The anhydrous sugar has m 132-135o. It has RF 0.8 on TLC (Silica Gel, and 1:3:3 CHCl3/butanone:/MeOH). The undecaacetate has been purified through an alumina column by elution with CHCl3, and recrystallised from EtOH/MeOH/H2O (3:2:5), with m 99-100o, [] D +92.8o (c 5.14, EtOH). [pK : Coccioli & Vicedomini Ann Chim (Rome) 66 269, 275 1976, 1H NMR: Suami et al. Carbohydr Research 26 234 1973, Beilstein 17 III/IV 3801, 17/8 V 403.]

비 호환성

Raffinose is incompatible with strong oxidizers.

Regulatory Status

Raffinose is a naturally occurring trisaccharide and is consumed as part of a normal diet.

라피노오스 준비 용품 및 원자재

원자재

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