이피엔
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이피엔 속성
- 녹는점
- 36℃
- 끓는 점
- 371.1°C (estimate)
- 밀도
- 1.3 g/cm3
- 증기압
- 3,000 at 100 °C (quoted, Verschueren, 1983)
- 굴절률
- 1.6021 (589.3 nm 25℃)
- 인화점
- 2 °C
- 저장 조건
- APPROX 4°C
- 용해도
- Miscible with acetone, benzene, methanol, isopropanol, toluene, and xylene (Windholz et al., 1983)
- 수용성
- 6.6mg l-1(20°C, 추정)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- Merck
- 13,3656
- BRN
- 2542580
- 노출 한도
- NIOSH REL: TWA 0.5 mg/m3, IDLH 5 mg/m3; OSHA PEL: TWA 0.5 mg/m3; ACGIH TLV: TWA 0.5 mg/m3.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T+,N,Xn,F | ||
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위험 카페고리 넘버 | 27/28-50/53-36-20/21/22-11 | ||
안전지침서 | 22-36/37-45-60-61-16 | ||
유엔번호(UN No.) | 3018 | ||
OEB | C | ||
OEL | TWA: 0.5 mg/m3 [skin] | ||
WGK 독일 | 3 | ||
RTECS 번호 | TB1925000 | ||
위험 등급 | 6.1(a) | ||
포장분류 | II | ||
유해 물질 데이터 | 2104-64-5(Hazardous Substances Data) | ||
독성 | LD50 in female, male rats (mg/kg): 7.7, 36 orally; 25, 230 dermal (Gaines) | ||
IDLA | 5 mg/m3 | ||
기존화학 물질 | KE-28417 | ||
유해화학물질 필터링 | 97-1-238 | ||
함량 및 규제정보 | 물질구분: 유독물질; 혼합물(제품)함량정보: 이피엔 및 이를 1% 이상 함유한 혼합물 |
그림문자(GHS): | |||||||||||||||
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신호 어: | Danger | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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이피엔 C화학적 특성, 용도, 생산
화학적 성질
EPN is a light yellow crystalline solid with an aromatic odor (as a pesticide) or a brown liquid above 36°C물리적 성질
Yellow to brown crystalline powder with an aromatic-like odor.용도
EPN is used to control chewing insects, especially lepidopterous larvae in cotton, rice, fruit and vegetables.일반 설명
Light yellow crystalline powder with an aromatic odor. Used as an insecticide for cotton and an acaricide.공기와 물의 반응
Insoluble in water. Hydrolyzed by alkali [EPA, 1998].반응 프로필
Organophosphates, such as EPN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.위험도
A cholinesterase inhibitor, absorbed by skin, use may be restricted. Questionable carcinogen.건강위험
EPN may be fatal if swallowed. It is poisonous if inhaled and extremely hazardous by skin contact. Repeated exposure may, without symptoms, be increasingly hazardous. The estimated fatal oral dose is 0.3 grams for a 150 lb. (70 kg) person.화재위험
(Non-Specific -- Organophosphorus Pesticide, n.o.s.) EPN may burn but does not ignite readily. Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Avoid strong oxidizers. Hydrolyzed by alkali.농업용
Insecticide: Banned for use in the EU. All registered uses of EPN in the U.S. were canceled by the U.S. EPA on August 31, 1988. Effective June 9, 1993, the U.S. EPA announced the revocation of all tolerances for residues of the insecticide상품명
NIAGARA®[C]; PIN®; SANTOX®; TRIPLE KILL T®[C]; VETO®[C]Safety Profile
Poison by ingestion, skin contact, and intraperitoneal routes. An experimental teratogen. A cholinesterase inhibitor. Ths material is extremelyhazardous on contact with skin, inhalation, or ingestion. A highly toxic insecticide. When heated to decomposition it emits highly toxic fumes of SOx, POx, NOx, and phosphme. See also PARATHION, NITRO COMPOUNDS OF AROMATIC HYDROCARBONS, PHOSPHINE, and SULFIDES잠재적 노출
EPN is used in preparation of emulsifiable, granular or wettable powder insecticides for cotton. A potential danger to those involved in the manufacture, formulation and application of this material.환경귀착
Biological. From the first-order biotic and abiotic rate constants of EPN in estuarine water and sediment/water systems, the estimated biodegradation half-lives were 6.2 and 9.2 days, respectively (Walker et al., 1988).Soil. Though no products were reported, the half-life in soil is 15–30 days (Hartley and Kidd, 1987).
Photolytic. EPN may undergo direct photolysis since the insecticide showed some absorption when a 1,4-dioxane was irradiated with UV light (l >290 nm) (Gore et al., 1971).
Chemical/Physical. On heating, EPN is converted to the S-ethyl isomer (Worthing and Hance, 1991). Releases toxic fumes of phosphorus, nitrogen and sulfur oxides when heated to decomposition (Sax and Lewis, 1987; Lewis, 1990). Rapidly hydrolyzed in alkaline solutions to p-nitrophenol, alcohol and benzene thiophosphoric acid (Sittig, 1985).
신진 대사 경로
EPN is degraded and deactivated in soil, plants and animals by a series of hydrolytic, dealkylation and oxidative desulfuration steps, ultimately to give phenylphosphonate. The metabolic pathway may or may not proceed via activation to the oxon, which is not usually detected in appreciable quantities as it metabolically unstable. A detoxification reaction via reduction of the nitro group to afford amino-EPN has been shown to take place in anaerobic soil, bacteria and animals. Uncommonly for organophosphates, hydroxylation of the phenyl ring also occurs in rats and hens.운송 방법
UN2783 Organophosphorus pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.비 호환성
Contact with oxidizers may cause the release of phosphorous oxides. Contact with strong reducing agents, such as hydrides; may cause the formation of flammable and toxic phosphine gas. Contact with alkalies causes decomposition (hydrolysis) producing p-nitrophenol.폐기물 처리
EPN plant wastes are treated by preaeration, activated sludge treatment; recycle, chlorination and final polishing where additional natural biological stabilization occurs. EPN is also relatively rapidly hydrolyzed in alkaline solution to benzene thiophosphoric acid; alcohol and p-nitrophenol and soil burial with alkali may be used. For large quantities, however, incineration is recommended. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.이피엔 준비 용품 및 원자재
원자재
티오포스포릴 염화물
4-니트로페놀소다염(2수화물)
O-에틸페닐클로리도티오포스포네이트
O-METHYL-L-TYROSINE
4-(4-nitrophenoxy)butanoic acid
EPN impurity 1
페닐티오포스포닉이염화물
준비 용품
이피엔 관련 검색:
NIFE디솔 메틸 파라싸이온(메틸 파라티온) 나이스타틴 파라싸이온(파라티온) NIZA티딘 이피엔
O-METHYL-L-TYROSINE
Nimodipine
DIMETHYL PHENYLPHOSPHONITE
Nitrendipine
EPN OXON
NIFEDIPINE IMPURITY ADIMETHYL 2,6-DIMETHYL-4-(2-NITROPHENYL) PYRIDINE-3,5-DICARBOXYLATE EPN(CRM STANDARD)
HISHICOLIN EPN
NIMODIPINE IMPURITY A2-METHOXYETHYL 1-METHYLETHYL 2,6-DIMETHYL-4-(3-NITROPHENYL) PYRIDINE-3,5-DICARBOXYLATE EPN(CRM STANDARD)
PHENYL-PHOSPHONOTHIOIC ACID PHENYL ESTER
EPN surrogate mix
EPN SOLUTION 1000UG/ML IN HEXANE 5ML
NALOXONE HYDROCHLORIDE EPN(CRM STANDARD)