눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P333+P313
피부자극성 또는 홍반이 나타나면 의학적인 조치·조언를 구하시오.
P337+P313
눈에 대한 자극이 지속되면 의학적인 조치· 조언를 구하시오.
P501
...에 내용물 / 용기를 폐기 하시오.
NFPA 704
1
2
0
바닐릴부틸에터 C화학적 특성, 용도, 생산
화학적 성질
Vanillyl butyl ether has a weak, vanillic, acidic odor.
용도
Vanillyl butyl ether is a compound hypothesized to have warming and vasodilation mechanisms when applied on the skin as a cream.
일반 설명
Vanillyl butyl ether is an alkoxy-substituted benzyl derivative mainly used as a flavoring agent.
부작용
Vanilloids contain vanillyl groups that bind to the transient receptor potential type V1 channel (Vanilloid receptor-1, TRPV1) that respond to noxious stimuli such as high temperatures and acidic pH. This causes neurons to release glutamate, adenosine triphosphate (ATP) and a variety of neuropeptides, resulting in the warming sensation. Vanillyl butyl ether causes serious eye irritation and may cause an allergic skin reaction.
Synthesis
At present, the synthesis of vanillyl butyl ether is mainly obtained by dehydrating and condensing vanillyl alcohol and n-butyl alcohol under an acid catalyst. However, the yield of the method is low mainly because water generated by the reaction can inhibit the etherification reaction. The common acid catalyst such as AlCl is used3、FeCl3It is easy to hydrolyze in the presence of water and lose its catalytic action. A new synthesis method comprises the following steps: dissolving vanillin in a solvent, adding a metal complex hydride and an alkylating reagent after uniformly stirring, reacting for 3-4 hours at 30-40 ℃ to obtain a vanillin alcohol ether solution, and separating and purifying the vanillin alcohol ether solution to obtain vanillin alcohol ether.
