COMBRETASTATIN A-4
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COMBRETASTATIN A-4 속성
- 녹는점
- 84.5-85.5°C
- 끓는 점
- 490.3±45.0 °C(Predicted)
- 밀도
- 1.184±0.06 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- DMSO: >10mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 9.65±0.10(Predicted)
- 색상
- 회백색
- Merck
- 14,2494
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 23/24/25-41 | ||
| 안전지침서 | 26-36/37-39-45 | ||
| 유엔번호(UN No.) | UN 2811 | ||
| WGK 독일 | 2 | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | Ⅲ | ||
| HS 번호 | 29095000 |
COMBRETASTATIN A-4 C화학적 특성, 용도, 생산
개요
Combrestatin A4 (CA4) is a potent inhibitor of tubulin polymerization and displays strong inhibitory activity on tumor cell growth. Combrestatin A4 was shown to inhibit tumor growth in several cell lines including IMR32 (neuroblastoma), Hs746T (gastric carcinoma), CFPAC-화학적 성질
Crystalline Powder용도
Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site.일반 설명
Combretastatin A4 belong to the class of colchicinoids compounds.생물학적 활성
Antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo . Acts by inhibiting tubulin polymerization (IC 50 = 2-3 μ M).Anticancer Research
It is a stilbenoid compound and the active among all combretastatins isolated fromthe bark of Combretum caffrum and is used for colon, lung, and leukemia cancertherapy (Shoeb 2006).COMBRETASTATIN A-4 준비 용품 및 원자재
원자재
준비 용품
COMBRETASTATIN A-4 공급 업체
글로벌( 283)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 |
stella@zetchem.com | China | 2141 | 58 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 |
sale02@cqherb.com | CHINA | 376 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
COMBRETASTATIN A-4 관련 검색:
4-하이드록시페펜에틸 알코올
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
Hydroxyecdysone
Artemether
beta-Sitosterol
alpha-Terpineol
hydroxygenkwanin
MOSLOFLAVONE
alpha-Cyperone
(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
Combretastatin A4 phosphate disodium salt
COMBRETASTATIN A-4
COMBRETASTATIN A1
(Z)-3-Ethoxy-6-(3,4,5-Trimethoxystyryl)Benzene-1,2-Diol
BENZENEACETIC ACID, 3-HYDROXY-4-METHOXY-A-[(3,4,5-TRIMETHOXYPHENYL)METHYLENE]-, (AE)-
2,3-DIMETHOXY-5-[(Z)-2-(4-METHOXY-3-(2-[2-((1-[(4-METHYLPHENYL)SULFONYL]-1H-INDOL-4-YL)OXY)ETHOXY]ETHOXY)PHENYL)ETHENYL]PHENYL METHYL ETHER
Combretastatin A-1 di-O-phosphate tetra-sodium salt
3-(3-Hydroxy-4-methoxy-phenyl)-2-(3,4,5-trimethoxy-phenyl)-acrylic acid