CX-4945
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- $10 - $4300
- Product name: CX-4945
- CAS: 1009820-21-6
- MF: C19H12ClN3O2
- MW: 349.77
- EINECS:
- MDL Number:MFCD13184796
- Synonyms:5-[(3-chlorophenyl)amino]-Benzo[c]-2,6-naphthyridine-8-carboxylic acid;CX-4945;CX-4945 Silmitasertib;CX-4945, CX4945;Silmitasertib(CX-4945);5-[(3-Chlorophenyl)amino]benzo[c]-2,6-naphthyridine-8-carboxylic acid CX-4945 (Silmitasertib);CX-4945, >=98%;CX-4945 (SILMITASERTIB);CX 4945; CX4945
68 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Atlantic Research Chemicals
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 10mM(1mLinDMSO)
- 50.00mg
- 500μg
- 10mM(in 1mL DMSO)
- 100.00mg
- 250.00mg
- 500mg
- 10mM*1mLinDMSO
- 1000mg
- 5000mg
- 10000mg
- 1gm:
- 10mM(in1mLDMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- 10g
- EvaluationSample
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 98%
- Packaging1mg
- Price$10
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 98%
- Packaging5mg
- Price$18
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 98%
- Packaging10mg
- Price$23
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 98%
- Packaging50mg
- Price$68
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 98%
- Packaging100mg
- Price$83
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 98%
- Packaging250mg
- Price$139
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 96%
- Packaging1g
- Price$507
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 96%
- Packaging5g
- Price$1492
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA00039R
- Product descriptionCX-4945 96%
- Packaging10g
- Price$2482
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10308
- Product descriptionCX-4945 98%
- Packaging5G
- Price$1750
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10308
- Product descriptionCX-4945 98%
- Packaging1G
- Price$450
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10308
- Product descriptionCX-4945 98%
- Packaging100MG
- Price$100
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10308
- Product descriptionCX-4945 98%
- Packaging25MG
- Price$40
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3629-M001
- Product descriptionCX-4945 . hydrochloride ≥98%
- Packaging1mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3629-M005
- Product descriptionCX-4945 . hydrochloride ≥98%
- Packaging5mg
- Price$170
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3629-M025
- Product descriptionCX-4945.hydrochloride ≥98%
- Packaging25mg
- Price$495
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00039R | CX-4945 98% | 1mg | $10 | 2026-05-25 | Buy |
| aablocks | AA00039R | CX-4945 98% | 5mg | $18 | 2026-05-25 | Buy |
| aablocks | AA00039R | CX-4945 98% | 10mg | $23 | 2026-05-25 | Buy |
| aablocks | AA00039R | CX-4945 98% | 50mg | $68 | 2026-05-25 | Buy |
| aablocks | AA00039R | CX-4945 98% | 100mg | $83 | 2026-05-25 | Buy |
| aablocks | AA00039R | CX-4945 98% | 250mg | $139 | 2026-05-25 | Buy |
| aablocks | AA00039R | CX-4945 96% | 1g | $507 | 2026-05-25 | Buy |
| aablocks | AA00039R | CX-4945 96% | 5g | $1492 | 2026-05-25 | Buy |
| aablocks | AA00039R | CX-4945 96% | 10g | $2482 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10308 | CX-4945 98% | 5G | $1750 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10308 | CX-4945 98% | 1G | $450 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10308 | CX-4945 98% | 100MG | $100 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10308 | CX-4945 98% | 25MG | $40 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-3629-M001 | CX-4945 . hydrochloride ≥98% | 1mg | $70 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3629-M005 | CX-4945 . hydrochloride ≥98% | 5mg | $170 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3629-M025 | CX-4945.hydrochloride ≥98% | 25mg | $495 | 2021-12-16 | Buy |
Properties
Boiling point :568.5±50.0 °C(Predicted)
Density :1.490
storage temp. :Store at -20°C
solubility :≥103.5 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Orange powder.
pka :2.96±0.30(Predicted)
color :Yellow to orange
InChI :InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)
InChIKey :MUOKSQABCJCOPU-UHFFFAOYSA-N
SMILES :C1(NC2=CC=CC(Cl)=C2)C2=C(C=NC=C2)C2=CC=C(C(O)=O)C=C2N=1
Density :1.490
storage temp. :Store at -20°C
solubility :≥103.5 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Orange powder.
pka :2.96±0.30(Predicted)
color :Yellow to orange
InChI :InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)
InChIKey :MUOKSQABCJCOPU-UHFFFAOYSA-N
SMILES :C1(NC2=CC=CC(Cl)=C2)C2=C(C=NC=C2)C2=CC=C(C(O)=O)C=C2N=1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||||
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Description
CX-4945 is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki = 0.38 nM) that competes with ATP by filling the small ATP binding site on the catalytic CK2α subunit, conferring selectivity. It inhibits proliferation in a panel of cancer cell lines that overexpress CK2 and prevents tumor growth of breast and pancreatic cancer cell xenografts in mice. CX-4945 blocks survival and induces apoptosis in cancer stem cells and is effective against glioblastomas and acute myeloid leukemia cells. CX-4945 also inhibits Cdc2-like kinases (Clk; IC50s = 82.3, 3.8, and 90 nM for Clk1, Clk2, and Clk3, respectively), interfering with alternative splicing.More related product prices
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Suppliers and manufacturers
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