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Ceftizoxime

Ceftizoxime Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Ceftizoxime
CAS:68401-81-0
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:Ceftizoxime
CAS:68401-81-0
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: PI & PI BIOTECH INC.
Tel: 020-81716320
Email: Sales@pipitech.com
Products Intro: Product Name:Ceftizoxime
CAS:68401-81-0
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com Remarks:(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Ceftizoxime
CAS:68401-81-0
Purity:98% Package:1g/5g
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name: Ceftizoxime
CAS: 68401-81-0
Purity:99% Package:1kg;7USD

Lastest Price from Ceftizoxime manufacturers

  • Ceftizoxime
  • US $7.00 / kg
  • 2019-07-06
  • CAS: 68401-81-0
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100kg
Ceftizoxime Basic information
Product Name:Ceftizoxime
Synonyms:EPOCELIN;CEFTIZOXIME;CEFTIZOXIME ACID;(6r-(6-alpha,7-beta(z)))-l)(methoxyimino)acetyl)amino)-8-oxo;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-(((2-amino-4-thiazoly;7-Amino-3-[[[2,5-Dihydro-6-Hydroxy-2-Methyl-5-Oxo-1,2,4-Trizin-3-Yl]-Thio]Methyl]-Cephalosporanic Acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, [6R-[6α,7β(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-
CAS:68401-81-0
MF:C13H13N5O5S2
MW:383.41
EINECS:
Product Categories:
Mol File:68401-81-0.mol
Ceftizoxime Structure
Ceftizoxime Chemical Properties
Melting point 227° (dec)
density 1.89±0.1 g/cm3(Predicted)
pkapKa 2.1 (Uncertain)
Merck 14,1951
CAS DataBase Reference68401-81-0(CAS DataBase Reference)
Safety Information
RTECS XI0367375
HS Code 2941906000
ToxicityLD50 intravenous in rat: 8gm/kg
MSDS Information
Ceftizoxime Usage And Synthesis
UsesAntibacterial.
DefinitionChEBI: A parenteral third-generation cephalosporin, bearing a 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino group at the 7beta-position.
Brand nameCefizox (Astellas).
Antimicrobial activityA semisynthetic cephalosporin supplied as the sodium salt. The properties are very similar to those of cefotaxime, but it lacks the acetoxymethyl group at position C-4 and is therefore not subject to deacetylation. Activity against common pathogenic bacteria (Table 13.4) is very similar to that of cefotaxime.
A 500 mg intramuscular injection achieves a plasma concentration of around 14 mg/L. A concentration of 85–90 mg/L is produced 30 min at the end of a 30-min intravenous infusion. The plasma half-life is 1.3–1.9 h. Protein binding is 30%. It is well distributed. In children with meningitis receiving 200–250 mg/kg per day in four equally divided doses for 14–21 days, mean CSF concentrations 2 h after a dose were 6.4 mg/L on day 2 and 3.6 mg/L on day 14.
About 70–90% of the dose is recovered in the urine in the first 24 h, principally by glomerular filtration. Probenecid increases the plasma half-life by about 50%. In patients receiving 1 g intravenously over 30 min, the plasma elimination half-life rose to 35 h when the corrected creatinine clearance was <10 mL/ min. It is partly removed by peritoneal and hemodialysis.
Adverse reactions and clinical use are similar to those of cefotaxime.
Ceftizoxime Preparation Products And Raw materials
Raw materialsEthyl acetate-->Magnesium sulfate-->Glyoxylic acid-->Palladium carbon fine chemical catalyzer-->Thiazole
Tag:Ceftizoxime(68401-81-0) Related Product Information
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