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Bisacodyl

Bisacodyl Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Bisacodyl
CAS:603-50-9
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Shanghai Bojing Chemical Co.,Ltd.
Tel: +86-21-37122233
Email: Candy@bj-chem.com
Products Intro: Product Name:Bisacodyl
CAS:603-50-9
Purity:99% Package:1kg;25kg;200kg Cardboard barrels Remarks:White powder
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:603-50-9
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: PI & PI BIOTECH INC.
Tel: 18371201331
Email: Sales@pipitech.com
Products Intro: Product Name:Bisacodyl
CAS:603-50-9
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com Remarks:4,4′-(Pyridin-2-ylmethylene)diphenyl diacetate
Company Name: Shanghai Yingrui Biopharma Co., Ltd.
Tel: +86-21-33585366 E-mail:sales03@shyrchem.com
Email: sales03@shyrchem.com
Products Intro: Product Name:Bisacodyl
CAS:603-50-9
Purity:0.98 Package:100g;250g;500g;1kg

Lastest Price from Bisacodyl manufacturers

  • Bisacodyl
  • US $0.00 / KG
  • 2021-06-11
  • CAS:603-50-9
  • Min. Order: 100g
  • Purity: 98%+
  • Supply Ability: 100kg
  • Bisacodyl
  • US $100.00 / KG
  • 2021-05-21
  • CAS:603-50-9
  • Min. Order: 1ASSAYS
  • Purity: 99%
  • Supply Ability: 1000t
  • top quality Bisacodyl
  • US $120.00 / KG
  • 2021-05-13
  • CAS:603-50-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 9000kg/per week
Bisacodyl Basic information
Product Name:Bisacodyl
Synonyms:2-(4,4’-diacetoxydiphenylmethyl)pyridine;2-(4,4'-Diacetoxydiphenylmethyl)pyridine;4,4'-(2-Pyridylmethylene)diphenol diacetate;4,4'-(2-Pyridylmethylene)diphenol diacetate (ester);4,4’-(2-pyridinylmethylene)bis-phenodiacetate(ester);4,4’-(2-pyridylmethylene)di-phenodiacetate(ester);4,4’-(2-pyridylmethylene)-diphenolacetate;4,4’-(2-Pyridylmethylene)-diphenolace-tate
CAS:603-50-9
MF:C22H19NO4
MW:361.39
EINECS:210-044-4
Product Categories:Inhibitors;API;Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;DULCOLAX
Mol File:603-50-9.mol
Bisacodyl Structure
Bisacodyl Chemical Properties
Melting point 138°C
Boiling point 493.21°C (rough estimate)
density 1.2545 (rough estimate)
refractive index 1.5614 (estimate)
storage temp. 2-8°C
solubility Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute mineral acids.
form neat
pka4.69±0.10(Predicted)
Water Solubility Soluble in alcohol (slightly), ether (slightly), chloroform, and acetone. Insoluble in water.
λmax220nm(MeOH)(lit.)
Merck 14,1242
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyKHOITXIGCFIULA-UHFFFAOYSA-N
CAS DataBase Reference603-50-9(CAS DataBase Reference)
NIST Chemistry ReferenceBisacodyl(603-50-9)
EPA Substance Registry SystemPhenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) (603-50-9)
Safety Information
Hazard Codes Xi
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS SM8750000
TSCA Yes
HS Code 2933399090
Hazardous Substances Data603-50-9(Hazardous Substances Data)
ToxicityLD50 orally in rats: >3 g/kg (Schmidt)
MSDS Information
Bisacodyl Usage And Synthesis
Chemical PropertiesCrystalline Solid
OriginatorDulcolax,Boehringer Ingelheim,US,1958
UsesCathartic.
UsesStimulant laxative.
Manufacturing ProcessPreparation of (4,4'-Dihydroxy-Diphenyl)-(Pyridyl-2)-Methane 70.0 grams of α-pyridine aldehyde are fed portionwise with stirring and cooling to a mixture of 200 grams of phenol and 100 cc of concentrated sulfuric acid. The reaction mixture is allowed to stand for a while with repeated stirring, whereby it becomes syrupy, neutralized with sodium carbonate, dissolved in methanol and filtered. The filtrate is introduced into a large quantity of water and the resulting precipitate is recrystallized from a methanol/water mixture. Colorless crystals are obtained of MP 254°C. When using zinc chloride or tin tetrachloride and warming to a temperature of about 50°C, a corresponding result is obtained.
Preparation of Bisacodyl: 5 grams of (4,4'-dihydroxy-diphenyl)-(pyridyl-2)- methane are heated with 5 grams of anhydrous sodium acetate and 20 cc of acetic anhydride for three hours over a boiling water bath. The cooled reaction mixture is poured into water, whereby after a while a colorless substance precipitates, which is filtered off with suction, washed with water and recrystallized from aqueous ethanol. Colorless bright crystals, MP 138°C are obtained.
Brand nameCorrectol Tablets, Caplets (Schering-Plough HealthCare); Dulcolax (Boehringer Ingelheim); Evac-Q-Tabs (Savage); Feen-a- Mint Tablets (Schering-Plough HealthCare); Modane (Savage); SK-Bisacodyl (SmithKline Beecham); Theralax (SmithKline Beecham).
Therapeutic FunctionLaxative
Veterinary Drugs and TreatmentsBisacodyl oral and rectal products are used as stimulant cathartics in dogs and cats.
Tag:Bisacodyl(603-50-9) Related Product Information
Bisacodyl Related Compound B (20 mg) (2,4'-(Pyridin-2-ylmethylene)diphenol) Bisacodyl EP Impurity A-d8 DL-α-Tocopherol Triacetin Glatiramer acetate POLY(VINYL ACETATE) Diphenolic acid Ammonium acetate 2,4,6-Collidine Ethyl acetate CARBINOXAMINE DIPHENYLDISULFONATE Pralmorelin ACETATE 4-Methylpyridine 5-Chlorovaleric acid Vinyl acetate 2-Chloro-5-chloromethylpyridine Bisphenol A