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NITROUS OXIDE Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:NITROUS OXIDE
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: Product Name:Nitrogen oxide (N2O)
Purity:99% Package:5KG;1KG
Company Name: Shanghai wechem chemical co., ltd  Gold
Tel: 021-5198 7501
Products Intro: Product Name:Nitrous Oxide
Purity:99.9+ Package:20KG/400.00;
Company Name: 9ding chemical ( Shanghai) Limited  
Tel: 4009209199
Products Intro: Product Name:Nitrous oxide Standard
Company Name: Shanghai Macklin Biochemical Co.,Ltd.  
Tel: 15221275939
Products Intro: Product Name:Nitrous oxide Standard
Purity:1000μg/ml Package:50ml
NITROUS OXIDE Basic information
Product Categories:refrigerants;Inorganics
Mol File:10024-97-2.mol
NITROUS OXIDE Chemical Properties
Melting point −91 °C(lit.)
Boiling point −88 °C(lit.)
density 1.23 g/cm3 (-89 ºC)
vapor density 1.53 (15 °C, vs air)
vapor pressure 51.7 mm Hg ( 21 °C)
refractive index 1.380
solubility At 20 °C and at a pressure of 101 kPa, 1 volume dissolves in about 1.5 volumes of water.
form colorless gas
Water Solubility slightly soluble H2O; soluble alcohol, ether, conc H2SO4 [HAW93]
Merck 13,6687
BRN 8137358
Stability:Oxidant, strongly supports combustion. May react violently with some materials. Thermal decomposition yields toxic products. Incompatible with aluminium, boron oxides, hydrazine, strong reducing agents.
CAS DataBase Reference10024-97-2(CAS DataBase Reference)
Safety Information
Hazard Codes O
Risk Statements 8
Safety Statements 38
RIDADR UN 1070 2.2
WGK Germany 1
RTECS QX1350000
HazardClass 2.2
MSDS Information
SigmaAldrich English
NITROUS OXIDE Usage And Synthesis
Chemical PropertiesColourless gas with sweetish odour
Chemical PropertiesNitrous oxide is a colorless gas. Slightly sweet odor. Shipped as a liquefied compressed gas.
Chemical PropertiesNitrous oxide is a nonflammable, colorless and odorless, sweettasting gas. It is usually handled as a compressed gas, stored in metal cylinders.
UsesNitrous Oxide is a noncombustible gas used as a propellant in certain dairy and vegetable fat whipped toppings contained in pressurized containers.
DefinitionChEBI: A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with ts non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
UsesNitrous oxide was discovered by Priestley. It is found in the atmosphere in trace concentrations. The gas is used as an anesthetic, especially in dentistry and minor surgery. It produces mild hysteria and laughter preceding the anesthetic effect, for which reason it also is called “laughing gas.” It is used as an aerosol propellant, an aerating agent for whipped cream, and an oxidizing agent at high temperatures. Nitrous oxide also is used in the preparation of nitrites and as a flame gas in flame atomic absorption spectrometry of metals.
Production MethodsNitrous oxide is prepared by heating ammonium nitrate to about 170°C. This reaction also forms water.
General DescriptionNITROUS OXIDE is a colorless, sweet-tasting gas. NITROUS OXIDE is also known as "laughing gas". Continued breathing of the vapors may impair the decision making process. NITROUS OXIDE is noncombustible but NITROUS OXIDE will accelerate the burning of combustible material in a fire. NITROUS OXIDE is soluble in water. Its vapors are heavier than air. Exposure of the container to prolonged heat or fire can cause NITROUS OXIDE to rupture violently and rocket. NITROUS OXIDE is used as an anesthetic, in pressure packaging, and to manufacture other chemicals.
Reactivity ProfileNITROUS OXIDE is an oxidizing agent. Nonflammable but supports combustion. Can explode at high temperature (after vaporization). Vapors can undergo a violent reaction with aluminum, boron, hydrazine, lithium hydride, phenyllithium, phosphine, sodium, tungsten carbide [Bretherick, 5th ed., 1995, p. 1686]. Contact of the cold liquefied gas with water may result in vigorous or violent boiling. If the water is hot, a liquid "superheat" explosion may occur. Pressures may build to dangerous levels if liquefied gas contacts water in a closed container [Handling Chemicals Safely 1980].
HazardSupports combustion, can form explosive mixture with air. Narcotic in high concentration. Central nervous system impairment, hematologic effects, and embryo/fetal damage. Questionable carcinogen.
Health HazardInhalation causes intense analgesia; concentrations of over 40-60% cause loss of consciousness preceded by hysteria. Contact of liquid with eyes or skin causes frostbite burn.
Fire HazardBehavior in Fire: Will support combustion, and may increase intensity of fire. Containers may explode when heated.
Pharmaceutical ApplicationsNitrous oxide and other compressed gases such as carbon dioxide and nitrogen are used as propellants for topical pharmaceutical aerosols. They are also used in other aerosol products that work satisfactorily with the coarse aerosol spray that is produced with compressed gases, e.g. furniture polish and window cleaner.
The advantages of compressed gases as aerosol propellants are that they are less expensive, of low toxicity, and practically odorless and tasteless. In contrast to liquefied gases, their pressures change relatively little with temperature. However, there is no reservoir of propellant in the aerosol, and as a result the pressure decreases as the product is used, changing the spray characteristics.
Misuse of a product by the consumer, such as using a product inverted, results in the discharge of the vapor phase instead of the liquid phase. Since most of the propellant is contained in the vapor phase, some of the propellant will be lost and the spray characteristics will be altered. Additionally, the sprays produced using compressed gases are very wet. However, recent developments in valve technology have reduced the risk of misuse by making available valves which will spray only the product (not propellant) regardless of the position of the container. Additionally, barrier systems will also prevent loss of propellant, and have found increased use with this propellant.
Therapeutically, nitrous oxide is best known as an anesthetic administered by inhalation. When used as an anesthetic it has strong analgesic properties but produces little muscle relaxation. Nitrous oxide is always administered in conjunction with oxygen since on its own it is hypoxic.
Safety ProfileModerately toxic by inhalation. Human systemic effects by inhalation: general anesthetic, decreased pulse rate without blood pressure fall, and body temperature decrease. An experimental teratogen. Experimental reproductive effects. Mutation data reported. An asphyxiant. Does not burn but is flammable by chemical reaction and supports combustion. Moderate explosion hazard; it can form an explosive mixture with air. Violent reaction with Al, B, hydrazine, LiH, LiC6H5, PH3, Na, tungsten carbide. Also self-explodes at high temperatures.
SafetyNitrous oxide is most commonly used therapeutically as an anesthetic and analgesic. Reports of adverse reactions to nitrous oxide therefore generally concern its therapeutic use, where relatively large quantities of the gas may be inhaled, rather than its use as an excipient.
The main complications associated with nitrous oxide inhalation occur as a result of hypoxia. Prolonged administration may also be harmful. Nitrous oxide is rapidly absorbed on inhalation.
Potential ExposureUsed as an anesthetic in dentistry and surgery; used as a gas in food aerosols, such as whipped cream; used in manufacture of nitrites; used in rocket fuels; in firefighting; diesel emissions. Large amounts of nitrous oxide will decrease the amount of available oxygen. Nitrous Oxide 2231 Oxygen should be routinely tested to ensure that it is at least 19% by volume.
First aidIf this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. If frostbite has occurred, seek medical attention immediately; do NOT rub the affected areas or flush them with water. In order to prevent further tissue damage, do NOT attempt to remove frozen clothing from frostbitten areas. If frostbite has NOT occurred, immediately and thoroughly wash contaminated skin with soap and water.
storageNitrous oxide is essentially nonreactive and stable except at high temperatures; at a temperature greater than 500°C nitrous oxide decomposes to nitrogen and oxygen. Explosive mixtures may be formed with other gases such as ammonia, hydrogen, and other fuels. Nitrous oxide should be stored in a tightly sealed metal cylinder in a cool, dry place.
ShippingUN1070 Nitrous oxide, compressed, Hazard Class: 2.2; Labels: 2.2-Nonflammable compressed gas; 5.1-Oxidizer; UN2201 Nitrous oxide, refrigerated liquid, Hazard Class: 2.2; Labels: 2.2-Nonflammable compressed gas; 5.1-Oxidizer. Cylinders must be transported in a secure upright position, in a well-ventilated truck. Protect cylinder and labels from physical damage. The owner of the compressed gas cylinder is the only entity allowed by federal law (49CFR) to transport and refill them. It is a violation of transportation regulations to refill compressed gas cylinders without the express written permission of the owner.
Purification MethodsWash the gas with concentrated alkaline pyrogallol solution, to remove O2, CO2, and NO2, then dry it by passing it through columns of P2O5 or Drierite, and collecting in a dry trap cooled in liquid N2. It is further purified by freeze-pump-thaw and distillation cycles under vacuum [Ryan & Freeman J Phys Chem 81 1455 1977, Schenk in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I pp 484-485 1963].
IncompatibilitiesNitrous oxide is a weak oxidizer. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Violent reactions with organic peroxides, hydrazine, hydrogen, hydrogen sulfide; lithium, boron, lithium hydride, sodium, aluminum, phosphine. This chemical is a strong oxidizer @ .300C and self-explodes at high temperature. May form explosive mixtures with ammonia, carbon monoxide; hydrogen sulfide; oil, grease and fuels.
IncompatibilitiesNitrous oxide is generally compatible with most materials encountered in pharmaceutical formulations, although it may react as a mild oxidizing agent.
Waste DisposalDisperse in atmosphere or spray on dry soda ash/lime with great care; then flush to sewer.
Regulatory StatusGRAS listed. Accepted for use as a food additive in Europe. Included in nonparenteral medicines licensed in the UK and USA. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
NITROUS OXIDE Preparation Products And Raw materials
Raw materialsAmmonium nitrate
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