ChemicalBook CAS DataBase List 3-(Chloromethyl)benzoyl chloride

3-(Chloromethyl)benzoyl chloride synthesis

7synthesis methods

Product Name:3-(Chloromethyl)benzoyl chloride
CAS Number:63024-77-1
Molecular formula:C8H6Cl2O
Molecular Weight:189.04

50-00-0 Synthesis

50-00-0
838 suppliers
$10.00/25g

98-07-7 Synthesis

98-07-7
320 suppliers
$13.00/25g

63024-77-1
125 suppliers
$8.00/1g

Yield: 95.2 %Chromat.

Reaction Conditions:

with aluminum (III) chloride in chloroform at 50 - 55; under 3000.3 Torr; for 18 h;Inert atmosphere;Autoclave;Solvent;Reagent/catalyst;Pressure;Temperature;

Steps:

Example 8 Example 8
The 90 ml chlorofrom input pressure, adding trichloromethyl phenyl 0.1mol, paraformaldehyde 0.12mol, anhydrous aluminium chloride 0.03mol, filled with nitrogen to 0.4 MPa, for 50 °C -55 ° C reaction time 18h, then cooling to room temperature, nitrogen releases, GC analysis is performed on a sample, area for the main peak area normalization 95.2%, with the 3-chloro methyl benzoyl chloride reference comparison, identified as the target product 3-(chloromethyl)benzoyl chloride.

References:

Fine Chemicals Co., Ltd. And Hubei Phase;Yi, Zhangguo;Yin, Shaohua;Dong, Xiaolu CN105384625, 2016, A Location in patent:Paragraph 0037; 0038

31719-77-4 Synthesis