METHYL 4-BROMO-3-METHOXYBENZOATE synthesis
- Product Name:METHYL 4-BROMO-3-METHOXYBENZOATE
- CAS Number:17100-63-9
- Molecular formula:C9H9BrO3
- Molecular Weight:245.07
106291-80-9
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77-78-1
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17100-63-9
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$9.00/250mg
Yield:17100-63-9 99%
Reaction Conditions:
with potassium carbonate in acetone; for 3 h;Heating / reflux;
Steps:
35.B
Step B. Methyl 4-bromo-3-methoxybenzoate A solution of methyl 4-bromo-3-hydroxybenzoate of Step A (27 mmol), potassium carbonate (33 mmol), and dimethyl sulfate (32 mmol) in acetone (40 mL) was stirred at reflux temperature under nitrogen atmosphere for three hours. The mixture was cooled and 5 mL of water was added. The acetone was evaporated and 30 mL of water was added. The product was extracted into dichloromethane. The organic solution was dried over anhydrous magnesium sulfate, filtered and evaporated to give the title compound (6.5 g, 99%) as a hard, white crystalline solid.
References:
US2006/199806,2006,A1 Location in patent:Page/Page column 23
106291-80-9
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$8.00/250mg
74-88-4
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17100-63-9
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$9.00/250mg
14348-38-0
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$14.00/1g
74-88-4
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$15.00/10g
17100-63-9
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$9.00/250mg
67-56-1
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56256-14-5
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$26.00/1g
17100-63-9
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$9.00/250mg
3556-83-0
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17100-63-9
130 suppliers
$9.00/250mg