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Tetrahydro-4H-pyran-4-one

Tetrahydro-4H-pyran-4-one Structure
Tetrahydro-4H-pyran-4-one structure
CAS No.
29943-42-8
Chemical Name:
Tetrahydro-4H-pyran-4-one
Synonyms
dihydro-2H-pyran-4(3H)-one;Oxan-4-one;TETRAHYDROPYRAN-4-ONE;4-THP;4-OXOTETRAHYDROPYRAN;4H-Pyran-4-one, tetrahydro-;EOS-60523;1KG,10KG,25KG;TETRAHYDRO-GAMM;4-Oxacyclohexanone
CBNumber:
CB3703050
Molecular Formula:
C5H8O2
Molecular Weight:
100.12
MDL Number:
MFCD00006581
MOL File:
29943-42-8.mol
MSDS File:
SDS
Last updated:2024-04-23 16:18:34
Request For Quotation

Tetrahydro-4H-pyran-4-one Properties

Boiling point 166-166.5 °C (lit.)
Density 1.084 g/mL at 25 °C (lit.)
refractive index n20/D 1.452(lit.)
Flash point 134 °F
storage temp. Inert atmosphere,Room Temperature
form Liquid
color Clear colorless to pale yellow
Water Solubility MISCIBLE
BRN 106463
InChIKey JMJRYTGVHCAYCT-UHFFFAOYSA-N
CAS DataBase Reference 29943-42-8(CAS DataBase Reference)
NIST Chemistry Reference 4H-Pyran-4-one, tetrahydro-(29943-42-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Warning
Hazard statements  H226
Precautionary statements  P210
Hazard Codes  Xi,F
Risk Statements  10-36/37/38
Safety Statements  24/25-36-26
RIDADR  UN 1224 3/PG 3
WGK Germany  3
F  10
Hazard Note  Keep Cold/Flammable/Irritant
HazardClass  3.2
PackingGroup  III
HS Code  29329995
NFPA 704
2
1 0

Tetrahydro-4H-pyran-4-one price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 198242 Tetrahydro-4H-pyran-4-one 99% 29943-42-8 1g $41.9 2024-03-01 Buy
Sigma-Aldrich 198242 Tetrahydro-4H-pyran-4-one 99% 29943-42-8 5g $135 2024-03-01 Buy
TCI Chemical T1806 Tetrahydro-4H-pyran-4-one >95.0%(GC) 29943-42-8 1g $37 2024-03-01 Buy
TCI Chemical T1806 Tetrahydro-4H-pyran-4-one >95.0%(GC) 29943-42-8 5g $104 2024-03-01 Buy
Alfa Aesar A19010 Tetrahydro-4H-pyran-4-one 98% 29943-42-8 1g $41.65 2024-03-01 Buy
Product number Packaging Price Buy
198242 1g $41.9 Buy
198242 5g $135 Buy
T1806 1g $37 Buy
T1806 5g $104 Buy
A19010 1g $41.65 Buy

Tetrahydro-4H-pyran-4-one Chemical Properties,Uses,Production

Description

Tetrahydro-4H-pyran-4-one is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes.
The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. Tetrahydro-4H-pyran-4-one is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3.

Application

Tetrahydro-4-pyrone is used in organic synthesis as a building block for more complex chemical structures because it participates in a variety of cycloaddition reactions. Tetrahydro-4H-pyran-4-one is employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid and it undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. Tetrahydro-4H-pyran-4-one is also employed in wittig reactions for the synthesis of penicillins and in a ring of vitamin D3. Additionally, tetrahydro-4-pyrone is used as solvents in some reactions.

Chemical Properties

colorless to light yellow liquid

Uses

Tetrahydro-4-pyrone is used in organic synthesis as building block for more complex chemical structures because it participate in a variety of cycloaddition reactions.

Purification Methods

Purify the pyrone by repeated distillation, preferably in a vacuum. [Baker J Chem Soc 296 1944, IR: Olsen & Bredoch Chem Ber 91 1589 1958.] The oxime has m 87-88o and b 110-111o/13mm [Cornubert et al. Bull Soc Chim Fr 36 1950]. The 4-nitrophenylhydrazone forms orange-brown needles from EtOH, m 186o [Cawley & Plant J Chem Soc 1214 1938]. [Beilstein 17 I 131, 17 II 287, 17 III/IV 4171, 17/9 V 21.]

Tetrahydro-4H-pyran-4-one synthesis

124-38-9
111-44-4
29943-42-8
Synthesis of Tetrahydro-4H-pyran-4-one from Carbon dioxide and 2,2'-Dichlorodiethyl ether

Tetrahydro-4H-pyran-4-one Preparation Products And Raw materials

Raw materials

Heptane ETHYLENE Copper Ethanol Acetone
Phosphoric acid Diethyl oxalate Nickel 2,2'-Bipyridine Sodium ethoxide
1,2,3,4-Tetrahydronaphthalene Sodium phosphate monobasic Aluminum chloride Dibutyl phthalate Ethyl acetate
Hydrochloric acid Dichloromethane Sodium hydroxide 3-Chloropropionyl chloride Magnesium sulfate
PETROLEUM ETHER

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Preparation Products

4-Aminotetrahydropyran hydrochloride 4-Aminotetrahydropyran 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL E-4-Hexen-1-ol

Tetrahydro-4H-pyran-4-one Suppliers

Global( 488)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaoxing Fangxiao Chemical Co., LTD 		+86-13456999252 +86-13868192239 kenny@fangxiaochem.com China 50 58
Suzhou Ryan Pharmachem Technology Co.,Ltd.
+86-512-68780025 +8618962125825 sales@ryanchem.com China 137 58
BTC pharm India
+918790379245 banny.janga@btcpharm.com India 1269 58
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		+8617702722807 admin@hbouhuang.com China 2259 58
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106 sales@frappschem.com China 885 50
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Supplier Advantage
Shaoxing Fangxiao Chemical Co., LTD 		58
Suzhou Ryan Pharmachem Technology Co.,Ltd.
58
BTC pharm India
58
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Ouhuang Engineering Materials (Hubei) Co., Ltd 		58
Frapp's ChemicalNFTZ Co., Ltd. 		50
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55

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View Lastest Price from Tetrahydro-4H-pyran-4-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tetrahydro-4H-pyran-4-one pictures 2024-04-23 Tetrahydro-4H-pyran-4-one
29943-42-8
 US $50.00 / kg 1kg 99.10% 50000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
Tetrahydro-4H-pyran-4-one pictures 2024-02-26 Tetrahydro-4H-pyran-4-one
29943-42-8
 US $0.00-0.00 / kg 1kg 99% Kgs BTC Nantong Pharmaceuticals Technology Co.,Ltd
Tetrahydro-4H-pyran-4-one pictures 2023-10-07 Tetrahydro-4H-pyran-4-one
29943-42-8
 US $15.00-3.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.

Tetrahydro-4H-pyran-4-one Spectrum

Tetrahydro-4H-pyran-4-one(29943-42-8)MSTetrahydro-4H-pyran-4-one(29943-42-8)1HNMRTetrahydro-4H-pyran-4-one(29943-42-8)IR1Tetrahydro-4H-pyran-4-one(29943-42-8)Raman

29943-42-8(Tetrahydro-4H-pyran-4-one)Related Search:

Tetrahydropyran Tetrahydrothiophen-3-one 4-Aminotetrahydropyran Centchroman Tetrahydro-4-pyranol
5-Formylsalicylic acid TETRAHYDRO-2H-PYRAN-4-YLACETYL CHLORIDE TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Tetrahydrothiopyran-4-one Tetrahydro-2H-pyran-4-carboxylic acid
Tetrahydropyranyl-4-acetic acid Tetrahydro-4H-Pyran-4-one TETRAHYDROPYRAN-2-METHANOL Ethyl Tetrahydropyran-4-Carboxylate ETHYL TETRAHYDROPYRAN-4-YL-ACETATE
(TETRAHYDRO-FURAN-3-YL)-ACETIC ACID Tetrahydropyran-4-carbaldehyde Tetrahydro-2H-pyran-4-carbonyl chloride

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Tetrahydro-4-pyrone TETRAHYDRO-GAMMA-PYRONE TETRAHYDRO-4H-PYRAN-4-ONE TETRAHYDRO-2H-PYRAN-4-ONE TetrahydroHpyranone Tetrahydropyran-4-on Tetrahydro-4H-pyran-4-one,98% Tetrahydo-4H-pyran-4-one Tetrahydro-4H-pyran-4-one 97% Tetranydropyran-4-one Tetrahydro-4-H-prran-one Tetrahydro-4H-pran-4-one Tetrahydro-4H-pyran-4-one, 97+% Four hydrogen pyran - 4 - ketone Tetrahydro-4H-pyran-4-one 4-tetrahydropyranone 2,3,5,6-Tetrahydropyran-4-one 3,5,6-Trihydro-2H-pyran-4-one 4-Oxotetrahydopyran 2,3,5,6-Tetrahydro-4H-pyran-4-one 2,3,5,6-Tetrahydro-4-pyranone 4-Oxacyclohexanone Tetrahydro-4-pyranone Tetrahydro-4H-pyran-4-one,99% Tetrahydro-4H-pyran-4-one,4-Oxotetrahydropyran Tetrahydro-4H-pyran- 4-Oxotetrahydropyran(Tetrahydropyran-4-one) etrahydro-4H-pyran-4-one Tetrahydro-4H-pyran-4-one, 99% 5GR TETRAHYDRO-4H-PYRAN-4-ONE FOR SYNTHESIS 4-Oxotrtrahydropyran 4-Oxotetrahydro-4H-pyran Tetrahydro-4H-Pyran-4-One (4-THP) EOS-60523 TETRAHYDRO-GAMM 1KG,10KG,25KG Tetrahydro-4H-pyran-4-one, 98%, for synthesis Tetrahydro-4H-pyran-4-one ISO 9001：2015 REACH TETRAHYDROPYRAN-4-ONE 4-OXOTETRAHYDROPYRAN 4-THP 4H-Pyran-4-one, tetrahydro- Oxan-4-one dihydro-2H-pyran-4(3H)-one Tetrahydropyranone 29943-42-8 C5H8O2 KETONE Building Blocks Heterocyclic Building Blocks Pyrans blocks Oxygen cyclic compounds Pyrans, Piperidines &Piperazines Carbonyl Compounds Ketone Pyrans, Piperidines & Piperazines Heterocycles