| Identification | More | [Name]
(R)-(-)-3-Pyrrolidinol hydrochloride | [CAS]
104706-47-0 | [Synonyms]
3-FURANAMINE, TETRAHYDRO-, (R)-, HYDROCHLORIDE
3-PYRROLIDINOL, HYDROCHLORIDE, (3R)-
3-PYRROLIDINOL, HYDROCHLORIDE, (3S)
3R-HYDROXYPYROLIDINE HCL
(R)-3-AMINOTETRAHYDROFURAN HYDROCHLORIDE
(R)-3-HYDROXYPYRROLIDINE HCL
(R)-(-)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE
(R)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE
(R)-(-)-3-PYRROLIDINOL HYDROCHLORIDE
(R)-(+)-3-PYRROLIDINOL HYDROCHLORIDE
(R)-3-PYRROLIDINOL HYDROCHLORIDE
(R)-PYRROLIDINE-3-OL HYDROCHLORIDE
(R)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE
(S)-3-HYDROXY PYRROLIDINE HCL
(S)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE
(S)-(-)-3-PYRROLIDINOL HYDROCHLORIDE
(S)-3-PYRROLIDINOL HYDROCHLORIDE
(S)-PYRROLIDIN-3-OL HCL
(S)-PYRROLIDINE-3-OL HYDROCHLORIDE
TIMTEC-BB SBB004272 | [EINECS(EC#)]
600-598-9 | [Molecular Formula]
C4H10ClNO | [MDL Number]
MFCD00272298 | [Molecular Weight]
123.58 | [MOL File]
104706-47-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
104-107 °C(lit.)
| [alpha ]
-7.6°(20/D, c=3,5, CH3OH) | [refractive index ]
-7.8 ° (C=3.5, MeOH) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Soluble in DMSO. | [form ]
Solid | [color ]
Pale Brown | [optical activity]
[α]20/D 7.6°, c = 3.5 in methanol | [Detection Methods]
T | [BRN ]
4450078 | [InChIKey]
QPMSJEFZULFYTB-PGMHMLKASA-N | [CAS DataBase Reference]
104706-47-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
3-10 | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
Llight brown crystalline | [Uses]
(R)-(-)-3-Pyrrolidinol hydrochloride is a chiral hydroxy derivative of pyrrlodine used in the preparation of chiral niologically active compounds such as muscarinic receptor antagonists and antimicrobial agents.
| [Purification Methods]
The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.] |
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