Back to ChemicalBook Home--->CAS DataBase List--->105-45-3

105-45-3

105-45-3 Structure

105-45-3 Structure
IdentificationMore
[Name]

Methyl acetoacetate
[CAS]

105-45-3
[Synonyms]

3-OXBUTANOIC ACID METHYL ESTER
3-OXOBUTANOIC ACID METHYL ESTER
3-OXOBUTYRIC ACID METHYL ESTER
ACETOACETIC ACID METHYL ESTER
ACETOACETIC ESTER (METHYL)
ACETYL METHYL ACETATE
ACM
MAA
METHYL 3-OXOBUTANOATE
METHYL 3-OXOBUTYRATE
METHYL 4-OXOBUTANOATE
METHYL ACETOACETATE
METHYL ACETOACETOACETATE
Methyl acetyl acetate
1-methoxybutane-1,3-dione
3-oxo-butanoicacimethylester
Acetoacetic methyl ester
acetoaceticmethylester
Butanoicacid,3-oxo-,methylester
Methyl acetylacetonate
[EINECS(EC#)]

203-299-8
[Molecular Formula]

C5H8O3
[MDL Number]

MFCD00008784
[Molecular Weight]

116.12
[MOL File]

105-45-3.mol
Chemical PropertiesBack Directory
[Appearance]

Colorless, clear liquid
[mp ]

-28 °C
[bp ]

169-170 °C70 mm Hg(lit.)
[density ]

1.077
[refractive index ]

n20/D 1.419(lit.)
[Fp ]

158 °F
[solubility ]

460 g/L (20°C)
[Water Solubility ]

460 g/L (20 ºC)
[Usage]

Methyl acetoacetate (MAA) is a starting material for the syntheses of alpha-substituted aceto-acetic esters and cyclic compounds, e.g. pyrazole, pyrimidine and coumarin derivatives.
[Merck ]

14,6009
[BRN ]

506727
[CAS DataBase Reference]

105-45-3(CAS DataBase Reference)
[NIST Chemistry Reference]

Butanoic acid, 3-oxo-, methyl ester(105-45-3)
[EPA Substance Registry System]

105-45-3(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36:Irritating to the eyes.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

1
[RTECS ]

AK5775000
[HS Code ]

29183000
[Safety Profile]

Moderately toxic by ingestion. A skin and severe eye irritant. Combustible when exposed to heat or flame. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS.
[Hazardous Substances Data]

105-45-3(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Methanol-->Ethyl acetoacetate-->Acetyl ketene-->METHANE
[Preparation Products]

4,6-Dimethylpyrimidine-5-carboxylic acid-->2,4-Dihydroxy-6-methylpyrimidine-->4-CHLORO-2-METHYLQUINOLINE-->Pirimiphos-methyl -->Fluvastatin sodium salt-->2-Acetylbutyrolactone-->Sethoxydim-->Diazinon-->Methyl 3-oxovalerate-->Isophytol-->LENAMPICILLIN-->DL-3-HYDROXYBUTYRIC ACID SODIUM SALT-->Nifedipine-->4-Hydroxy-2-methylquinoline-->5-Methyl-3-phenylisoxazole-4-carboxylic acid-->2-AMINO-3-CYANO-4-METHYL-5-CARBMETHOXY THIOPHENE-->5-AMINO-3-METHYL-THIOPHENE-2,4-DICARBOXYLIC ACID DIMETHYL ESTER-->MEVINPHOS-->Felodipine-->Ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate-->2,2-DIMETHYLCYCLOPENTANONE-->D-(-)-A-4-HYDROXYPHENYLGLYCINE DANE SALT METHYL POTASSIUM-->Sodium 2-propylpentanoate
Hazard InformationBack Directory
[General Description]

A clear colorless liquid. Flash point 158°F. Denser than water and slightly soluble in water. Vapors heavier than air.
[Reactivity Profile]

METHYL ACETOACETATE(105-45-3) is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides
[Air & Water Reactions]

Very slightly soluble in water.
[Hazard]

Toxic by ingestion and inhalation.
[Health Hazard]

May be harmful by inhalation, ingestion, or skin absorption. Causes eye irritation. May cause skin irritation.
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

MAA(105-45-3).msds
Spectrum DetailBack Directory
[Spectrum Detail]

Methyl acetoacetate(105-45-3) 1H NMR
Methyl acetoacetate(105-45-3) Raman
Methyl acetoacetate(105-45-3) 13C NMR
Methyl acetoacetate(105-45-3) IR1
Methyl acetoacetate(105-45-3) MS
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Methyl acetoacetate, 99+%(105-45-3)
[Alfa Aesar]

Methyl acetoacetate, 99%(105-45-3)
[Sigma Aldrich]

105-45-3(sigmaaldrich)
[TCI AMERICA]

Methyl Acetoacetate,>99.0%(GC)(105-45-3)
105-45-3 suppliers list
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: 86-18523575427
Fax:
Website: https://www.chemicalbook.com/ShowSupplierProductsList617604/0.htm
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-13650506873
Fax:
Website: www.chemdad.com
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86 592-605 1114
Fax:
Website: www.amoychem.com
Company Name: Haihang Industry Co.,Ltd
Tel: 86-531-88032799
Fax: +86 531 8582 1093
Website: www.haihangindustry.com
Company Name: career henan chemical co
Tel: +86-371-86658258
Fax:
Website: www.coreychem.com/index.html
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Fax:
Website: www.dakentech.com
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Fax:
Website: www.chemicalbook.com/ShowSupplierProductsList30845/0.htm
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Fax: +86-0592-6210733
Website: www.mainchem.com
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 86-0551-65418684 18949823763
Fax: 86-0551-65418684
Website: www.tnjchem.com
Company Name: Nanjing ChemLin Chemical Industry Co., Ltd.
Tel: 025-83697070;product@chemlin.com.cn
Fax:
Website: www.echemlin.cn
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Fax: 0371-55170693
Website: www.tianfuchem.net
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Fax: 0755-23311925
Website: www.chemicalbook.com/ShowSupplierProductsList30406/0_EN.htm
Company Name: -  Gold
Tel:0574-62093617
Fax:
Website:www.wanglong.com
Company Name: Nanjing Zhipu Chemical Co., Ltd  Gold
Tel:025-83172869*83172967*18851668089*13813022170
Fax:025-83311492
Website:www.chemicalbook.com/ShowSupplierProductsList20072/0.htm
Company Name: Creasyn Finechem(Tianjin) Co., Ltd.  
Tel:022-83945878-
Fax:022-83945176
Website:www.creasyn.com/
Company Name: J & K SCIENTIFIC LTD.  
Tel:010-82848833- ;010-82848833-
Fax:86-10-82849933
Website:www.jkchemical.com/
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel:+86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
Fax:+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)
Website:www.meryer.com
Company Name: Alfa Aesar  
Tel:400-610-6006; 021-67582000
Fax:021-67582001/03/05
Website:chemicals.thermofisher.cn
Tags:105-45-3 Related Product Information
63131-29-3 1655-07-8 6289-46-9 787-07-5 517-23-7 105-45-3 1694-31-1 143390-89-0 580-02-9 372-31-6 74223-64-6 141-97-9 32807-28-6 119-36-8 13831-30-6 298-00-0 96-33-3 29232-93-7