124-06-1

64-17-5

544-63-8

124-06-1

The general procedure for the synthesis of ethyl tetradecanoate from ethanol and myristic acid was as follows: myristic acid (12 g, 53 mmol) was dissolved in an ethanol solution (50 mL) containing 4% wt sulfuric acid, and the mixture was sonicated for 4.5 h using a Branson 1210 ultrasonic cleaner (Branson, Danbury, CT, USA) to promote the esterification reaction. After completion of the reaction, the solvent was removed by rotary evaporator. The residue was diluted with ethyl acetate (40 mL) and subsequently washed to neutrality with 5% wt sodium hydroxide solution. The organic layer was dried with anhydrous sodium sulfate, filtered and the solvent was evaporated to give 13.25 g of ethyl tetradecanoate as a pale yellow liquid in 98.43% yield. The product was analyzed by FT-IR showing characteristic absorption peaks: 2924 cm^-1 (C-H stretching vibration), 1735 cm^-1 (C=O ester group stretching vibration), 1458 cm^-1 (CH2 bending vibration), 1180 cm^-1 (C-O ester group stretching vibration). gC analysis showed that the product had a purity of 98.90%, retention time (tR) was 34.4 minutes, and the molecular ion peak [M-15]+ = 256 was detected by mass spectrometry.