| Identification | More | [Name]
Adiphenine hydrochloride | [CAS]
50-42-0 | [Synonyms]
2-DIETHYLAMINOETHYL DIPHENYLACETATE HYDROCHLORIDE
ADIPHENINE
ADIPHENINE HCL
ADIPHENINE HYDROCHLORIDE
ALPHA-PHENYLBENZENEACETIC ACID 2-[DIETHYLAMINO]ETHYL ESTER HYDROCHLORIDE
DIPHENYLACETIC ACID 2-(DIETHYLAMINO)ETHYL ESTER HYDROCHLORIDE
DIPHENYLACETYLDIETHYLAMINOETHANOL HYDROCHLORIDE
aceticacid,diphenyl-,2-(diethylamino)ethylester,hydrochloride
adifeninhydrochloride
adiphenhydrochloride
benzeneaceticacid,alpha-phenyl-,2-(diethylamino)ethyl-ester,hydrochloride
difacilhydrochloride
diphacilhydrochloride
diphenylacetatedudiethylamino-ethanolchlorhydrate
ethanol,2-(diethylamino)-,2,2-diphenylacetate,hydrochloride
patrovina
paxil(anticolinergic)
sentiv
spasmolytinhydrochloride
trasentinehydrochloride | [EINECS(EC#)]
200-036-9 | [Molecular Formula]
C20H25NO2 | [MDL Number]
MFCD00242658 | [Molecular Weight]
311.42 | [MOL File]
50-42-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
113-114° | [density ]
1.0555 (rough estimate) | [refractive index ]
1.5400 (estimate) | [storage temp. ]
Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Very Slightly) | [form ]
neat | [color ]
White | [Merck ]
14,161 | [InChI]
InChI=1S/C20H25NO2.ClH/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,19H,3-4,15-16H2,1-2H3;1H | [InChIKey]
LKPINBXAWIMZCG-UHFFFAOYSA-N | [SMILES]
C(C(=O)OCCN(CC)CC)(C1=CC=CC=C1)C1=CC=CC=C1.Cl | [CAS DataBase Reference]
50-42-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
AH2625000
| [HS Code ]
2922.19.7000 | [Toxicity]
LD50 i.p. in mice: 0.24 g/kg (Burtner, Cusic) |
| Hazard Information | Back Directory | [Originator]
Adiphenine
hydrochloride,Spectrum Chemicals and
Laboratory Products, Inc. | [Uses]
Adiphenine hydrochloride is an anticholinergic. Adiphenine hydrochloride is used as an antispasmodic.
| [Uses]
radioprotectant | [Manufacturing Process]
10.6 parts of α,α-diphenylacetic acid are treated with thionyl chloride and the
diphenylacetylchloride thus produced is caused to react with 5.9 parts of
diethylaminoethanol at 120°C. The α,α-diphenylacetic acid, 2-
(diethylamino)ethanol ester hydrochloride thus produced is crystallized from
ethyl acetate; it melts at 113-114°C. | [Therapeutic Function]
Anticholinergic, Spasmolytic, Smooth muscle relaxant | [in vivo]
Adiphenine (i.p.) prevents the hindleg tonic-extensor component of maximal electroshock seizures (MES), with an ED50 of 62 mg/kg in mice[3]. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
|