| Identification | More | [Name]
Aminodiphenylmethane hydrochloride | [CAS]
5267-34-5 | [Synonyms]
1,1-DIPHENYLMETHYLAMINE HYDROCHLORIDE
ALPHA-AMINODIPHENYLMETHANE HYDROCHLORIDE
AMINODIPHENYLMETHANE HCL
AMINODIPHENYLMETHANE HYDROCHLORIDE
BENZHYDRYLAMINE HYDROCHLORIDE
LABOTEST-BB LT00159614
PHENYLBENZENEMETHANAMINE HYDROCHLORIDE
benzhydrylammonium chloride
a-diphenylamine hydrochloride
BenzhydrylamineHCl,(Aminodiphenylmethanehydrochloride)
alpha-Aminodiphenylme
Benzenemethanamine, .alpha.-phenyl-, hydrochloride
BENZHYDRYLAMINEHCL | [EINECS(EC#)]
226-084-0 | [Molecular Formula]
C13H14ClN | [MDL Number]
MFCD00013023 | [Molecular Weight]
219.71 | [MOL File]
5267-34-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white to off-white crystalline powder | [Melting point ]
293-295 °C(lit.) | [Boiling point ]
205-207 °C(Press: 4 Torr) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
powder to crystal | [color ]
White to Almost white | [Sensitive ]
Hygroscopic | [Merck ]
14,1076 | [BRN ]
3914818 | [CAS DataBase Reference]
5267-34-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
29214990 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white crystalline powder | [Uses]
Benzhydrylamine Hydrochloride is used as molecular tools to block maturation of nuclear lamin A and decelerate cancer cell migration. | [Synthesis]
In the second step, benzophenone oxime (900 mg) was hydrogenated with a solution of concentrated hydrochloric acid (1.84 mL) in ethanol (50 mL) at atmospheric pressure in the presence of 10% Pd/C catalyst (100 mg). Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst and the filtrate was subsequently concentrated. The concentrated residue was suspended in ethyl acetate and the suspension was filtered again to give the final diphenylmethylamine hydrochloride (2.17 g) as a white solid. | [References]
[1] Patent: EP2511283, 2012, A1. Location in patent: Page/Page column 91
[2] Patent: US2013/45942, 2013, A1. Location in patent: Paragraph 0379
[3] Patent: JP2015/172077, 2015, A. Location in patent: Paragraph 0187 |
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