| Identification | More | [Name]
Ethyl 2-oxocyclopentanecarboxylate | [CAS]
611-10-9 | [Synonyms]
2-CARBETHOXYCYCLOPENTANONE
2-ETHOXYCARBONYLCYCLOPENTANONE
2-(ETHOXYCARBONYL)CYCLOPETNANONE
AKOS AU36-M83
CYCLOPENTANONE-2-CARBOXYLIC ACID ETHYL ESTER
ETHYL 2-CYCLOPENTANONE-1-CARBOXYLATE
ETHYL-2-CYCLOPENTANONECARBOXYLATE
ETHYL 2-OXOCYCLOPENTANECARBOXYLATE
ETHYL CYCLOPENTANONE-2-CARBOXYLATE
(R,S)-2-Oxo-cyclopentanecarboxylicacidethylester
2-Carbethoxy-1-cyclopentanone
2-Carboethoxycyclopentanone
2-Cyclopentanonecarboxylic acid ethyl ester
alpha-(Carboethoxy)cyclopentanone
Cylopenhtanone-2-carboxylicacidethylester
Ethyl 2-oxo-1-cyclopentanecarboxylate
Ethyl 2-oxoocyclopentanecarboxylate
Ethyl ester of 2-oxocyclopentanecarboxylic acid
Cyclopentanone-2-carboxylic acid ethyl ester~Ethyl 2-oxocyclopentanecarboxylate
Ehtyl 2-Oxocyclopentanecarboxylate | [EINECS(EC#)]
210-253-0 | [Molecular Formula]
C8H12O3 | [MDL Number]
MFCD00001412 | [Molecular Weight]
156.18 | [MOL File]
611-10-9.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colourless to pale yellow liquid | [Boiling point ]
102-104 °C/11 mmHg (lit.) | [density ]
1.054 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.452(lit.)
| [Fp ]
172 °F
| [storage temp. ]
2-8°C
| [form ]
Liquid | [pka]
12.02±0.20(Predicted) | [color ]
Clear colorless to pale yellow | [Water Solubility ]
insoluble | [Detection Methods]
HPLC,NMR | [BRN ]
387787 | [InChI]
InChI=1S/C8H12O3/c1-2-11-8(10)6-4-3-5-7(6)9/h6H,2-5H2,1H3 | [InChIKey]
JHZPNBKZPAWCJD-UHFFFAOYSA-N | [SMILES]
C1(C(OCC)=O)CCCC1=O | [LogP]
0.330 (est) | [Uses]
Pharmaceutical intermediate. | [CAS DataBase Reference]
611-10-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Cyclopentanecarboxylic acid, 2-oxo-, ethyl ester(611-10-9) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes .
S36/37:Wear suitable protective clothing and gloves .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
10 | [HazardClass ]
IRRITANT | [HS Code ]
29183000 |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Tetrahydrofuran-->Acetic acid-->Sodium-->Toluene-->Potassium tert-butoxide-->Diethyl adipate-->Cyclopentanecarboxylic acid, 1-bromo-2-oxo-, ethyl ester-->1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid, ethyl ester | [Preparation Products]
3-Indolepropionic acid-->1-Cyclopentene-1-carboxylic acid, 2-(benzoylamino)-, ethyl ester-->Naphth[2,3-b]oxiren-2(1aH)-one, 7,7a-dihydro-7-hydroxy-1a,7-dimethyl--->2-CYCLOPENTANONE CARBOXYLATE-->3-oxo-2-pentylcyclopentaneacetic acid-->7-Hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-4-one-->MDL-29951-->Monoethyl Adipate |
| Hazard Information | Back Directory | [Hazard]
Vapors are toxic, as is skin contact. | [Chemical Properties]
clear colourless to pale yellow liquid | [Synthesis Reference(s)]
Journal of the American Chemical Society, 85, p. 207, 1963 DOI: 10.1021/ja00885a021
The Journal of Organic Chemistry, 55, p. 5037, 1990 DOI: 10.1021/jo00304a014
Tetrahedron Letters, 22, p. 1353, 1981 DOI: 10.1016/S0040-4039(01)90316-8 | [General Description]
Phase-transfer benzylation reaction of ethyl 2-oxocyclopentanecarboxylate with benzyl bromide in microreactor has been investigated. Ethyl 2-oxocyclopentanecarboxylate participates in cobalt (II) Schiff′s base complex catalyzed oxidation of primary and secondary alcohols. |
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