| Identification | Back Directory | [Name]
Flutropium bromide | [CAS]
63516-07-4 | [Synonyms]
Ba 598
Flubron
Ba 598Br
Flutropium
Flutropiumbromid
flutropium bromide
[8-(2-Fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2,2-diphenylacetate bromide
(1R,5S,8-syn)-8-Methyl-8-(2-fluoroethyl)-3α-[[diphenyl(hydroxy)acetyl]oxy]-8-azoniabicyclo[3.2.1]octane
(endo，syn)-8-(2-Fluoroethyl)-3-[(hydroxyl-diphenylaeetyl)oxy]-8-methyl-8-azoniabicyclo[3．2．1]octane bromide
8-Azoniabicyclo[3.2.1]octane, 8-(2-fluoroethyl)-3-[(hydroxydiphenylacetyl)oxy]-8-methyl-, bromide, (endo,syn)-
8-Azoniabicyclo[3.2.1]octane, 8-(2-fluoroethyl)-3-[(hydroxydiphenylacetyl)oxy]-8-methyl-, bromide, (3-endo,8-syn)- | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C24H29BrFNO3 | [MDL Number]
MFCD00865207 | [MOL File]
63516-07-4.mol | [Molecular Weight]
478.39 |
| Hazard Information | Back Directory | [Description]
Flutropium bromide is an antitussive useful in the treatment of allergic rhinitis and in the
symptomatic relief of bronchial asthma and chronic bronchitis. Recent studies suggest that
flutropium bromide may have potential as a long-acting alternative to
P-sympathomimetics or the xanthines in the prophylaxis of obstructive airways disease. | [Originator]
Boehringer Ingelheim (W.Germany) | [Definition]
ChEBI: Flutropium bromide is the organic bromide salt of flutropium. It is used in Japan for the treatment asthma and chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist, an antispasmodic drug and an anti-asthmatic drug. It contains a flutropium. | [Brand name]
Flubron |
| Safety Data | Back Directory | [Toxicity]
LD50 in male, female mice, male, female rats (mg/kg): 12.5, 11.0, 16.4, 18.4 i.v.; 760, 810, 830, 740 orally (Bauer, Fügner) |
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