Back to ChemicalBook Home--->CAS DataBase List--->64-18-6

64-18-6

64-18-6 Structure

64-18-6 Structure
IdentificationMore
[Name]

Formic acid
[CAS]

64-18-6
[Synonyms]

ALDEHYDE C1
FORMALDE-FRESH
FORMALDE-FRESH SOLUTION
FORMALDE-FRESH SOLUTION, BUFFERED
FORMALDEHYDE
FORMALDEHYDE, BUFFERED
FORMALDEHYDE, CARSON-MILLON
FORMALDEHYDE DEVELOPING SOLUTION
FORMALDEHYDE SOLUTION
FORMALDEHYDI
FORMALIN
FORMALIN, CARSONS
FORMALIN, NEUTRAL
FORMALIN NEUTRAL BUFFER
FORMALIN, NEUTRAL BUFFERED
FORMALIN NEUTRAL SODIUM SALT
FORMIC ALDEHYDE
FORMOL
METHANAL
METHANONE
[EINECS(EC#)]

200-001-8
[Molecular Formula]

CH2O2
[MDL Number]

MFCD00003274
[Molecular Weight]

46.03
[MOL File]

64-18-6.mol
Chemical PropertiesBack Directory
[Appearance]

Clear, colorless liquid
[Appearance]

Colorless, fuming liquid; penetrating odor. strong reducing agent. Soluble in water, alcohol, and ether. Combustible.
[Appearance]

Formic acid is a colorless, flammable, fuming liq uid. Pungent odor.
[mp ]

8.2-8.4 °C(lit.)
[bp ]

101 °C
[density ]

1.22
[vapor density ]

1.03 (vs air)
[vapor pressure ]

52 mm Hg ( 37 °C)
[FEMA ]

2487
[refractive index ]

n20/D 1.377
[Fp ]

133 °F
[storage temp. ]

2-8°C
[Stability:]

Stable. Substances to be avoided include strong bases, strong oxidizing agents and powdered metals, furfuryl alcohol. Combustible. Hygroscopic. Pressure may build up in tightly closed bottles, so bottles should be opened carefully and vented periodically.
[Water Solubility ]

MISCIBLE
[Sensitive ]

Hygroscopic
[Merck ]

14,4241
[BRN ]

1209246
[Uses]

Dyeing and finishing of textile; leather treatment; chemicals (formates, oxalic acid, organic esters); manufacture of fumigants, insecticides, refrigerants; solvents for perfumes, lacquers; electroplating; brewing (antiseptic); silvering glass; cellulose
[Uses]

Formic Acid is a flavoring substance that is liquid and colorless, and possesses a pungent odor. it is miscible in water, alcohol, ether, and glycerin, and is obtained by chemical synthesis or oxidation of methanol or formaldehyde.
[CAS DataBase Reference]

64-18-6(CAS DataBase Reference)
[NIST Chemistry Reference]

Formic acid(64-18-6)
[EPA Substance Registry System]

64-18-6(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

T,C,Xi
[Risk Statements ]

R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R34:Causes burns.
R40:Limited evidence of a carcinogenic effect.
R43:May cause sensitization by skin contact.
R35:Causes severe burns.
R36/38:Irritating to eyes and skin .
[Safety Statements ]

S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
[RIDADR ]

UN 1198 3/PG 3
[WGK Germany ]

2
[RTECS ]

LP8925000
[F ]

10
[HazardClass ]

8
[PackingGroup ]

II
[HS Code ]

29151100
[Safety Profile]

Poison by inhalation, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Mutation data reported. Corrosive. A skin and severe eye irritant. A substance migrating to food from packaging materials. Combustible liquid when exposed to heat or flame; can react vigorously with oxidizing materials. Explosive reaction with furfuryl alcohol, H202, T1(NO3)3*3H2O nitromethane, P2O5. To fight fire, use CO2, dry chemical, alcohol foam. When heated to decomposition it emits acrid smoke and irritating fumes.
[Hazardous Substances Data]

64-18-6(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium hydroxide-->Methanol-->Sulfuric acid -->Triethylamine-->Ammonia-->Sodium methanolate-->Phosphorous acid-->CARBON MONOXIDE-->PETROLEUM ETHER-->Sodium formate-->Methyl formate-->METALLURGICAL COKE
[Preparation Products]

[4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDIN-5-YL]METHANOL-->8-BROMO-3-METHYL-3,7-DIHYDRO-PURINE-2,6-DIONE-->Sulfur Yellow GC-->2-Ethylbutyric acid -->3,4-DIHYDROISOQUINOLINE-->Benzyl formate-->N-Methylformamide-->1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE-->2-METHANESULFONYL-4-METHYL-PYRIMIDINE-->5-Ethyl-2-pyridineethanol-->METHYL PENT-4-YN-2-YLCARBAMATE-->Sulfur Red Brown B3R-->3,7-DIMETHYL-7-OCTEN-1-OL-->5-Methyl-2-(methylsulfonyl)pyrimidine ,97%-->5-AMINO-6-CHLORO-PYRIMIDIN-4-OL-->4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBALDEHYDE-->7-Hydroxy-6-methoxy-3,4-dihydroisoquinoline-->1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID-->(1H-INDAZOL-3-YL)-ACETIC ACID-->Diethoxymethyl acetate-->Epoxidized soya bean oil-->C.I.BASICBLUE22-->dimethyl dodecyl thioic propylene betaine-->5,7-dichlorooxazolo[5,4-d]pyrimidine-->GUANINE SULFATE-->1-FORMYL-4-METHYLPIPERAZINE-->4-Azabenzimidazole-->1,3,5-TRIMETHYL-1,3,5-TRIPHENYLCYCLOTRISILOXANE-->4,4'-Methylenebis(N,N-dimethylaniline)-->3-FLUORO-N-METHYLANILINE-->2-Hydroxy-N-(4-methoxyphenyl)-11H-benzo[a]carbazole-3-carboxamide-->Pigment Yellow 83-->2-AMINO-4,4'-DICHLORODIPHENYL ETHER-->2-OXO-2,3-DIHYDRO-BENZOOXAZOLE-5-CARBOXYLIC ACID-->1-(2-Hydroxyethyl)-4-methylpiperazine-->1H-Benzimidazole-5-carboxylic acid-->3-METHYLTHIOPHENE-2-CARBONITRILE-->Geranyl formate-->ETHYL 2,4-DICHLOROBENZOATE-->CINNAMYL FORMATE
Hazard InformationBack Directory
[General Description]

A colorless liquid with a pungent odor. Flash point 156°F. Density 10.2 lb/gal. Corrosive to metals and tissue.
[Reactivity Profile]

FORMIC ACID(64-18-6) reacts exothmerically with all bases, both organic (for example, the amines) and inorganic. Reacts with active metals to form gaseous hydrogen and a metal salt. Reacts with cyanide salts to generate gaseous hydrogen cyanide. Reacts with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides to generate flammable or toxic gases. Reacts with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Reacts with carbonates and bicarbonates to generate carbon dioxide but still heat. Can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. May initiate polymerization reactions or catalyze other chemical reactions. A mixture with furfuryl alcohol exploded [Chem. Eng. News 18:72(1940)].
[Air & Water Reactions]

Fumes in air. Soluble in water with release of heat.
[Hazard]

Corrosive to skin and tissue.
[Health Hazard]

Liquid causes skin and eye burns. Vapors are irritating and painful to breath. Vapor exposure may cause nausea and vomiting.
[Potential Exposure]

Formic acid is a strong reducing agent and is used as a decalcifier. It is used in pharmaceuticals; in dyeing textiles and finishing color-fast wool; electroplat ing, coagulating latex rubber; regeneration old rubber, and dehairing, plumping, and tanning leather. It is also used in the manufacture of acetic acid, airplane dope; allyl alcohol; cellulose formate; phenolic resins; and oxalate; and it is used in the laundry, textile, insecticide, refrigeration, and paper industries; as well as in drug manufacture.
[Fire Hazard]

Special Hazards of Combustion Products: Toxic vapor generated in fires
[First aid]

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, includ ing resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medi cal attention. If victim is conscious, administer water or milk. Do not induce vomiting.
[Shipping]

UN1779 Formic acid, with>85% acid by mass, Hazard class: 8; Labels: 8-Corrosive material, 3-Flammable liquid
[Incompatibilities]

Vapors may form explosive mixture with air. A medium strong acid and a strong reducing agent. Violent reaction with oxidizers, furfuryl alcohol; hydrogen peroxide; nitromethane. Incompatible with strong acids; bases, ammonia, aliphatic amines; alkanolamines, isocya nates, alkylene oxides; epichlorohydrin. Decomposes on heating and on contact with strong acids forming carbon monoxide. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrideds and active metals. Contact with active metals or nitrides form flammable gaseous hydrogen. Incompatible with strongly oxidizing acids, peroxides, and hydroperoxides. Attacks metals: aluminum, cast iron and steel; many plastics, rubber and coatings.
[Waste Disposal]

Incineration with added solvent. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥ kg/mo) must conform with EPA regulations governing storage, transpor tation, treatment, and waste disposal.
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

formic acid(64-18-6).msds
Questions And AnswerBack Directory
[General Description]

Formic acid (HCO2H), also called methanoic acid, is the simplest carboxylic acid. Formic acid was first isolated by the distillation of ant bodies and was named after the Latin formica, meaning “ant.” Its proper IUPAC name is now methanoic acid. Industrially, formic acid is produced by treatment of carbon monoxide with an alcohol such as methanol (methyl alcohol) in the presence of a catalyst.
Formic acid is found both naturally occurring and frequently synthesized in laboratories. It is most naturally found in the stings and bites of many insects, including bees and ants, as a chemical defense mechanism.
[Properties]

FORMIC ACID is a colorless liquid with a pungent odor. It is a stable corrosive, combustible, and hygroscopic chemical substance. It is incompatible with H2SO4, strong caustics, furfuryl alcohol, hydrogen peroxide, strong oxidisers, and bases and reacts with strong explosion on contact with oxidising agents.
Due to the −CHO group, Formic acid imparts some of the character of an aldehyde. It can form salt and ester; can react with amine to form amide and to form ester by addition reaction with unsaturated hydrocarbon addition. It can reduce the silver ammonia solution to produce a silver mirror, and make the potassium permanganate solution fade, which can be used for the qualitative identification of formic acid.
As a carboxylic acid, formic acid shares most of the same chemical properties in reacting with alkalis to form water soluble formate. But formic acid is not a typical carboxylic acid as it can react with alkenes to form formate esters.
[Production]

  • Since 1896, formic aid is made in European countries by the action of sulfuric acid upon sodium formate, which is produced from carbon monoxide and sodium hydroxide.
  • In 1980, the United States Science and Design Corporation developed a carbonylation of methanol to produce formic acid with an annual output of 20,000 tons. The reaction formula is:
  • The mixture of liquid ammonia and methanol is used to absorb carbon monoxide at 70 ° C and 32.5 MPa to form formamide, which is then hydrolyzed in an aqueous acid solution.
  • Use oxalic acid and glycerol as raw materials being co-heated at 110 ° C to generate oxalic acid monoglyceride. Heat it to decarboxylate and form Monoglycerides formate, then hydrolyze it to obtain formic acid.
  • After the formic acid aqueous solution is obtained, a dehydrating agent (for anhydrous magnesium sulfate, anhydrous copper sulfate, etc.), extractive distillation (extracting agent may be trimethylamine, picoline, etc.) may be used for dehydration and purification, and anhydrous formic aic can be obtained.
Spectrum DetailBack Directory
[Spectrum Detail]

Formic acid(64-18-6)IR1
Formic acid(64-18-6)MS
Formic acid(64-18-6)Raman
Formic acid(64-18-6)13CNMR
Formic acid(64-18-6)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Formic acid, for analysis, 99+%(64-18-6)
[Alfa Aesar]

Formic acid, ACS, 96+%(64-18-6)
[Sigma Aldrich]

64-18-6(sigmaaldrich)
[TCI AMERICA]

Formic Acid  [for LC-MS],>98.0%(GC)(64-18-6)
64-18-6 suppliers list
Company Name: Hubei xin bonus chemical co. LTD
Tel: 13657299721
Fax:
Website: www.chemicalbook.com/ShowSupplierProductsList1549548/0.htm
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86 (0)592-605 1114
Fax:
Website: www.amoychem.com
Company Name: Chemwill Asia Co.,Ltd.
Tel: 86-21-51086038
Fax: 86-21-51861608
Website: www.chemwill.com
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-188-71490254
Fax:
Website: www.chemicalbook.com/ShowSupplierProductsList31316/0.htm
Company Name: Haihang Industry Co.,Ltd
Tel: 86-531-88032799
Fax: +86 531 8582 1093
Website: www.haihangindustry.com
Company Name: Hebei Guanlang Biotechnology Co., Ltd.
Tel: +8619930501651
Fax:
Website: www.chemicalbook.com/ShowSupplierProductsList31448/0.htm
Company Name: Hebei Chisure Biotechnology Co., Ltd.
Tel: +8613292890173
Fax: 0311 66567340
Website: www.chemicalbook.com/ShowSupplierProductsList30840/0.htm
Company Name: career henan chemical co
Tel: +86-371-86658258
Fax:
Website: www.coreychem.com
Company Name: Hebei Guanlang Biotechnology Co., Ltd.
Tel: +86-0311-66562153 whatsapp +8615203118427
Fax: +86-0311-66562153
Website: www.chemicalbook.com/ShowSupplierProductsList30475/0_EN.htm
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Fax:
Website: www.dakentech.com
Company Name: Hebei Minshang Biotechnology Co., Ltd
Tel: +86-13230167943
Fax:
Website: www.chemicalbook.com
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Fax: +86-0592-6210733
Website: www.mainchem.com
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 86-0551-65418684 18949823763
Fax: 86-0551-65418684
Website: www.tnjchem.com
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Fax: 0371-55170693
Website: www.tianfuchem.net
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Fax: 0755-23311925
Website: www.chemicalbook.com/ShowSupplierProductsList30406/0_EN.htm
Company Name: VOT INTERNATIONAL BUSINESS CO.,LTD  Gold
Tel:0536-2456718
Fax:0536-8231856
Website:www.votchemical.com
Company Name: Chengdu RunZeBenTu Chemical Co., Ltd  Gold
Tel:13096311329 028-88469284 qq:616445927
Fax:028-88469284
Website:www.rzbtsj.com
Company Name: Shanghai Macklin Biochemical Co.,Ltd.  Gold
Tel:15221275939
Fax:021-51821727
Website:www.macklin.cn
Tags:64-18-6 Related Product Information
55896-93-0 1333-86-4 115-77-5 1310-73-2 79-09-4 65-85-0 302-79-4 117-81-7 77-92-9 64-18-6 145040-37-5 1477-50-5 59-30-3 84-74-2 57-11-4 535-11-5 600-00-0 5445-17-0