| Identification | More | [Name]
4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol | [CAS]
83282-91-1 | [Synonyms]
2,3,5,6-Tetrafluoro-4-methoxybenzyl alcohol
4-Methoxymethyl-2,3,5,6-Tetrafluorobenzyl
2,3,5,6-TETRAFLUORO-4-(METHOXYMETHYL)BENZYL ALCOHOL | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C9H8F4O2 | [MDL Number]
MFCD08741397 | [Molecular Weight]
224.15 | [MOL File]
83282-91-1.mol |
| Questions And Answer | Back Directory | [Synthesis]
Method 1: Using 1,2,4,5-tetrafluorobenzene as a starting material, a reaction is carried out to produce 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol:
Method 2: 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol is produced by selective methylation of 2,3,5,6-tetrafluoro-1,4-benzenedimethanol. The specific steps are as follows:
1) 2,3,5,6-tetrafluoro-1,4-benzenedimethanol reacts with an inorganic base in water and a water-immiscible organic solvent selected from hydrocarbons and ethers,
2) Dimethyl sulfate and, optionally, a water-immiscible organic solvent are added to the reaction mixture to give the target compound, 4-methoxy-2,3,5,6-tetrafluorobenzyl alcohol. In step 2), the reaction must be carried out in water and a water-immiscible organic solvent selected from hydrocarbons and ethers. Examples of water-immiscible organic solvents include aromatic hydrocarbons such as toluene and xylene, aliphatic hydrocarbons such as hexane and heptane, and others such as tert-butyl methyl ether. |
| Chemical Properties | Back Directory | [Melting point ]
51-53°C | [Boiling point ]
214 ºC | [density ]
1.407 | [Fp ]
107 ºC | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform, Methanol | [form ]
Solid | [pka]
12.85±0.10(Predicted) | [color ]
White | [InChI]
InChI=1S/C9H8F4O2/c1-15-3-5-8(12)6(10)4(2-14)7(11)9(5)13/h14H,2-3H2,1H3 | [InChIKey]
YFHZSPDQKWFAPH-UHFFFAOYSA-N | [SMILES]
C1(CO)=C(F)C(F)=C(COC)C(F)=C1F | [CAS DataBase Reference]
83282-91-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl Alcohol is used as a reagent in the synthesis of Metofluthrin; a potent new synthetic pyrethroid with high vapor activity against mosquitos. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956 |
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https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
China Langchem Inc.
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| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
SHANG FLUORO
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| Telephone: |
021-65170832 15601903708 |
| Website: |
http://www.shangfluoro.com |
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