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Sitagliptin Produkt Beschreibung

Sitagliptin Struktur
486460-32-6
CAS-Nr.
486460-32-6
Englisch Name:
Sitagliptin
Synonyma:
Janumet;Hsdb 7516;C53323300;Sitagliptin;Sitaglipitin;Sitagliptin-D4;Unii-qfp0p1dv7z;Sitagliptin API;Sitagliptin base;Sitagliptin-D4 HCL
CBNumber:
CB01449778
Summenformel:
C16H15F6N5O
Molgewicht:
407.32
MOL-Datei:
486460-32-6.mol

Sitagliptin Eigenschaften

Sicherheit

Giftige Stoffe Daten 486460-32-6(Hazardous Substances Data)

Sitagliptin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is a first-in-class oral drug launched for the treatment of type 2 diabetes. It acts by slowing the inactivation of incretins, which are endogenous peptides involved in the physiologic regulation of glucose homeostasis. Incretin hormones, including glucagonlike peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are released by the intestine throughout the day, and levels are increased in response to a meal. When blood glucose concentrations are normal or elevated,GLP-1 and GIP increase the synthesis and release of insulin from pancreatic b cells via intracellular signaling pathways involving cAMP. GLP-1 also lowers glucagon secretion from pancreatic αcells, which leads to reduced hepatic glucose production.

Originator

Merck (US)

Verwenden

Labeled Sitagliptin , intended for use as an internal standard for the quantification of Sitagliptin by GC- or LC-mass spectrometry.

Definition

ChEBI: A triazolopyrazine that exhibits hypoglycemic activity.

Trademarks

Januvia

Sitagliptin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Sitagliptin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 228)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Shenzhen Nexconn Pharmatechs Ltd
15013857715
admin@nexconn.com CHINA 3193 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21726 58
Hi-Tech Chemistry Corp
0519-86626038
yuhh@hitechem.com CHINA 811 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2861 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 661 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24191 60
AB PharmaTech,LLC
323-480-4688
323-480-4688 sales01@abpharmatechusa.com United States 989 55

486460-32-6()Verwandte Suche:


  • Sitagliptin free base
  • (3R)-3-AMino-1-[3-(trifluoroMethyl)-5,6,7,8-tetrahydro-1,2,4-riazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-rifluorophenyl) butan-1-one
  • (R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
  • Sitagliptin (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
  • Sitagliptin base
  • (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
  • Sitagliptin
  • 1,2,4-Triazolo(4,3-A)pyrazine, 7-((3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl)-5,6,7,8-tetrahydor-3-(trifluoromethyl)-
  • Hsdb 7516
  • Janumet
  • Unii-qfp0p1dv7z
  • C53323300
  • Metformin / sitagliptin
  • Metformin hydrochloride mixture with sitagliptin phosphate
  • Metformin mixture with sitagliptin
  • Sitagliptin-D4
  • Sitagliptin-D4 HCL
  • Sitagliptin API
  • Tadalafil and its interMediate
  • 1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)-
  • (S)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
  • Sitaglipitin
  • Sitagliptin (Metformin,MK-0431)
  • 486460-32-6
  • 1011232-08-8
  • C16H15F6N5O
  • API
  • -
  • Pharmaceutical intermediate
  • Heterocycles
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