3-Hydroxy-p-anisaldehyd
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- CAS-Nr.
- 621-59-0
- Bezeichnung:
- 3-Hydroxy-p-anisaldehyd
- Englisch Name:
- Isovanillin
- Synonyma:
- 3-HYDROXY-4-METHOXYBENZALDEHYDE;ISOVANILIN;sovanillin;5-Formylguaiacol;3-Hydroxy-4-methoxy;Benzaldehyde,3-hydroxy-4-methoxy-;NSC 82996;ISOVANILLIN;lsovanillin;AKOS B022473
- CBNumber:
- CB0705725
- Summenformel:
- C8H8O3
- Molgewicht:
- 152.15
- MOL-Datei:
- 621-59-0.mol
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3-Hydroxy-p-anisaldehyd Eigenschaften
- Schmelzpunkt:
- 113-116 °C
- Siedepunkt:
- 179 °C15 mm Hg(lit.)
- Dichte
- 1.20
- Dampfdruck
- 0Pa at 20℃
- Brechungsindex
- 1.4945 (estimate)
- Flammpunkt:
- 179°C/15mm
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Löslichkeit
- Soluble in acetone and methanol.
- pka
- pK1:8.889 (25°C)
- Aggregatzustand
- crystalline
- Farbe
- faintly brown
- Wasserlöslichkeit
- 2.27g/L at 20℃
- Sensitive
- Air Sensitive
- BRN
- 1073021
- InChIKey
- JVTZFYYHCGSXJV-UHFFFAOYSA-N
- LogP
- 0.95 at 20℃
- CAS Datenbank
- 621-59-0(CAS DataBase Reference)
- NIST chemische Informationen
- Benzaldehyde, 3-hydroxy-4-methoxy-(621-59-0)
- EPA chemische Informationen
- Benzaldehyde, 3-hydroxy-4-methoxy- (621-59-0)
3-Hydroxy-p-anisaldehyd Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Light Tan Cyrstalline Solid
Verwenden
3-Hydroxy-4-methoxybenzaldehyde was used as starting reagent during the two-step stereoselective synthesis of the anticancer drug (
Z)-combretastatin A-4 and glycitein synthesis.
Application
Isovanillin is a kind of fragrance and isomer of vanillin. it has unique properties than vanillin, its fragrance can change with the change of ambient temperature, so it is especially suitable for special cosmetics and some special fragrance industries. Isovanillin is a selective inhibitor of aldehyde oxidase. It is not a substrate of that enzyme, and is metabolized by aldehyde dehydrogenase into isovanillic acid, which could make it a candidate drug for use in alcohol aversion therapy.
synthetische
Synthesis of isovanillin: 4-Hydroxybenzaldehyde is used as raw material, firstly react with bromine to obtain 3-bromo-4-hydroxybenzaldehyde, then react with methyl iodide to obtain 3-bromo-4-methoxybenzaldehyde, and then hydrolyzed under the action of sodium hydroxide and cuprous chloride to produce isovanillin. The yield was 64.1%.
Allgemeine Beschreibung
3-Hydroxy-4-methoxybenzaldehyde on condensation with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide yields Schiff-bases. It undergoes condensation reaction with1-azabicyclo[2.2.2]octan-3-one to give (
Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one.
läuterung methode
Crystallise isovaniline from H2O or *C6H6. The oxime has m 147o. [Beilstein 8 IV 1764.]
3-Hydroxy-p-anisaldehyd Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-Hydroxy-p-anisaldehyd Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 702)Lieferanten
621-59-0(3-Hydroxy-p-anisaldehyd)Verwandte Suche:
- ISOVANILLIN
- 3-HYDROXY-4-ANISALDEHYDE
- 3-HYDROXYANISALDEHYDE
- 3-HYDROXY-P-ANISALDEHYDE
- AKOS B022473
- AKOS BBS-00003278
- TIMTEC-BB SBB008245
- 2-Methoxy-5-formylphenol
- 4-METHOXY-3-HYDROXYBENZALDEHYDE
- 3-Hydroxy-4-methoxybenzaldehyd
- p-Anisaldehyde,3-hydroxy-
- 3-Hydorxy-4-Methoxy Benzoic Acid
- 3-Hydroxy-4-methylhoxy benzaldehyde
- ISOVANILLIN, MATRIX SUBSTANCE FOR MALDI- MS
- Isovanilllin
- Isovanillin, 3-Hydroxyanisaldehyde
- Isovanillin, 3-Hydroxy-p-anisaldehyde, 5-Formylguaiacol, 5-Formyl-2-methoxyphenol
- 3-Hydroxy-4-Methoxybenzaldehyde, 97+%
- Extraordinary fragrance LanSu
- Isovanillin Synonyms 3-Hydroxy-4-methoxybenzaldehyde
- Isovanillin >=95.0%
- 3-hydroxy-4-methoxy-benzaldehyd
- 3-hydroxy-p-anisaldehyd
- Benzaldehyde,3-hydroxy-4-m
- 3-HYDROXY-4-METHOXYBENZALDEHYDE / ISOVANILLIN
- 3-HYDROXY-4-METHOXYBENZALDEHYDE 99+%
- ISOVANILLIN (3-HYDROXY-4-METHOXYBENZALDEHYDE)
- NSC 82996
- 3-Hydroxy-4-methoxybenzaldehyde
4-Methoxy-3-hydroxybenzaldehyde
- 3-Hydroxy-4-methoxybenzaldehyde, 98+%
- 3-Hydroxyanisaldehyde, Isovanillin
- 3-Hydroxy-4-methoxybenzaldehyde, 3-Hydroxyanisaldehyde
- 3-Hydroxy-para-anisaldehyde
- 5-Formyl-2-methoxyphenol
- Isovanicaline
- Isovanillicaldehyde
- Isovanilline
- Oxy-3 methoxy-4 benzaldehyde
- oxy-3methoxy-4benzaldehyde
- p-Anisaldehyde, 3-hydroxy-
- 3-Hydroxy-4-Methoxybenzaldehyde, 98% 5GR
- 3-Hydroxy-4-methoxybenzaL
- Isovanillin>
- 3-Hydroxy-4-methoxybenzaldehyde, 99%, for synthesis
- Isovanillin,>98%
- Gefitinib Impurity 42 (Isovanillin)
- Gefitinib Impurity 91
- 3-Hydroxy-4-methoxybenzaldehyde USP/EP/BP
- Entacapone Impurity 79
- Bloom Tech Chemical Reagent Isovanillin CAS?621-59-0
- ISOVANILINE Extra Pure
- 11 Dihydrocarbamezer
- 11-hydroxy-10
- ISOVANILIN
- 3-HYDROXY-4-METHOXYBENZALDEHYDE
- 3-Hydroxy-4-methoxy
- 5-Formylguaiacol
- Benzaldehyde,3-hydroxy-4-methoxy-
