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Fursultiamin Produkt Beschreibung

Fursultiamine Struktur
804-30-8
CAS-Nr.
804-30-8
Bezeichnung:
Fursultiamin
Englisch Name:
Fursultiamine
Synonyma:
ttfd;judolor;linamin;Retar B1;adventan;diteftin;Alinaxin;alinaminf;Aliaron F;fursultiamin
CBNumber:
CB1161096
Summenformel:
C17H26N4O3S2
Molgewicht:
398.54
MOL-Datei:
804-30-8.mol

Fursultiamin Eigenschaften

Schmelzpunkt:
130-136°C (decompos.)
Siedepunkt:
652.3±55.0 °C(Predicted)
Dichte
1.29
Brechungsindex
1.6270 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
14.42±0.10(Predicted)
CAS Datenbank
804-30-8(CAS DataBase Reference)

Sicherheit

Toxizität LD50 in rats (mg/kg): 2200 orally; 540 i.p. (Yurugi, Fushimi)

Fursultiamin Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Alinamin F,Takeda,Japan,1961

Verwenden

Fursultiamine is an oral source of thiamine, used in comparative pharmacokinectic analysis of thiamine and it’s phosphorylated metabolites administered as multivitamin preparations, identification of drug candidate against prostate cancer from aspect of somatic cell reprogramming, therapeutic tool in number of human neurological diseases.

Manufacturing Process

To a solution of 20 parts of thiamine hydrochloride in 30 parts of water is added an aqueous solution of sodium hydroxide (7.2 parts of NaOH in 30 parts of water), and the mixture is cooled with water. The mixture is allowed to stand for 30 minutes, 60 parts of chloroform is added, followed by a solution of 30 parts of crude sodium tetrahydrofurfurylthiosulfate in 30 parts of water, and the whole is stirred for 30 minutes. The chloroform layer is separated and the aqueous layer is extracted twice with 20 parts of chloroform. All the chloroform solutions are combined and shaken with 50 parts of 5% hydrochloric acid. The acid solution is decolorized and neutralized with alkali carbonate, whereupon thiamine tetrahydrofurfuryl disulfide separates out in the resinous state but soon solidifies [MP 129°C (decamp.)] . The yield is 16 parts. Recrystallization from ethyl acetate gives colorless prisms melting at 132°C (decomp.).

Therapeutic Function

Enzyme cofactor vitamin

Fursultiamin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Fursultiamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 125)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Shandong Natural Micron Pharm Tech Co.,LTD
13752232623
info@nmpharmtech.com CHINA 2736 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Shanghai Time Chemicals CO., Ltd.
+8618017249410 +86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com China 1807 55
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29953 58
HubeiwidelychemicaltechnologyCo.,Ltd
18627774460
faith@widelychemical.com CHINA 743 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu zzwenxi@126.com CHINA 13187 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17384 58

804-30-8(Fursultiamin)Verwandte Suche:


  • ((tetrahydrofurfuryl)dithio)-1-butenyl)-
  • adventan
  • alinaminf
  • diteftin
  • fursultiamin
  • n-(4-amino-2-methylpyrimidin-5-ylmethyl)-n-[4-hydroxy-1-methyl- 2-(tetrahydrofurfuryldithio)but-1-enyl]formamide
  • Fursutiamine
  • Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]- (6CI, 8CI)
  • Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-
  • N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]formamide
  • Retar B1
  • Tetrahydrofurfuryl thiamine disulfide
  • Thiamin tetrahydrofurfuryl disulfide
  • N-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-N-[(E)-5-hydroxy-3-(oxolan-2-ylmethyldisulfanyl)pent-2-en-2-yl]formamide
  • Fursultiamine (base and/or unspecified salts)
  • N-(-4-amino-2-methyl-5-pyrimidinylmethyl)-N-(-4-hydroxyl-1-methyl-2-tetrahyclrofurfury(dithio-1-bute
  • Fursultiamine###Fursultiamine Hcl
  • FURSULTIAMINE
  • Fursultiamine Base
  • Fursultiaminlim
  • N-(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]forma
  • FURSULTIAMINE HYDROCHLORIDE
  • Aliaron F
  • Alinaxin
  • N-[(2-Methyl-4-amino-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydrofuran-2-yl)methyl]dithio]-1-butenyl]formamide
  • judolor
  • linamin
  • retar-b(sub1)
  • thiaminetetrahydrofurfuryldisulfide
  • ttfd
  • Fursultiamine Hydrochloride RS
  • Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-
  • THIAMINE TETRAHYDROFURFURYL DISULFIDE (TTFD)
  • Fursultiamine USP/EP/BP
  • Fursultiamine HCL JP USP/EP/BP
  • Derivative Fursultiamine
  • N-((4-Amino-2-methylpyrimidin-5-yl)methyl)-N-(5-hydroxy-3-(((tetrahydrofuran-2-yl)methyl)disulfanyl)pent-2-en-2-yl)formamide
  • 804-30-8
  • C17H26N4O3S2
  • Vitamins and derivatives
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