4-tert-Butylphenol Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
WEISSE HYGROSKOPISCHE FLOCKEN.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: 0,08 ppm, 0,5 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(2); Hautresorption; Sensibilisierung der Haut; Schwangerschaft: Gruppe D (DFG 2006).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation des Aerosols und über die Haut.
INHALATIONSGEFAHREN
Verdampfung bei 20°C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim Dispergieren schnell erreicht werden.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt stark die Augen, die Hautund die Atemwege. Möglich sind Auswirkungen auf die Haut mit nachfolgender Depigmentierung.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Hautkontakt kann Dermatitis hervorrufen. Wiederholter oder andauernder Kontakt kann zu Hautsensibilisierung führen. Möglich sind Auswirkungen auf Leber, Milz, Schilddrüseund Nervensystem mit nachfolgenden Funktionsstörungen.
LECKAGE
Verschüttetes Material in abdichtbaren Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgfältig sammeln. An sicheren Ort bringen. Persönliche Schutzausrüstung: Atemschutzgerät, A/P2-Filter für organische Dämpfe und schädlichen Staub. NICHT in die Umwelt gelangen lassen.
R-Sätze Betriebsanweisung:
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Para-tertiary-butylphenol formaldehyde resin (PTBPF-
R) is a polycondensate of para-tertiary-butylphenol
and formaldehyde. Major occupational sources are
neoprene glues and adhesives in industry, in the
shoemaking and leather industry or in car production.
It is also used as a box preservative in box and
furniture manufacture, and in the production of
casting moulds, car-brake linings, insulated electrical
cables, adhesives, printing inks and paper laminates.
Para-tertiary-butyl-phenol is the sensitizer.
Chemische Eigenschaften
4-tert-Butylphenol is a white to pale yellow crystalline solid at room temperature and is sold in solid form as flakes or briquettes. 4-tert-butylphenol is employed in coating products, polymers, adhesives, sealants and for the synthesis of other substances.
The major use is as a monomer in chemical synthesis, e.g. for the production of polycarbonate, phenolic resins, epoxy resins. PtBP is used as a chain terminator in the synthesis of polycarbonate polymers. The main uses of polycarbonate are in compact discs, DVD and CD Rom manufacture.
Occurrence
Reported found in origanum (Coridothymus cap. (L.) Richb.)
Verwenden
4-tert-Butylphenol is a phenol derivative. Its contact with skin may lead to leukoderma. It is widely used in the polymer industry. Reaction of 4-tert-Butylphenol with mushroom tyrosinase has been reported to afford 4-t-butyl-o-benzoquinone and kinetics of this enzymatic reaction has been investigated.
synthetische
Prepared by heating phenol with isobutanol in the presence of zinc chloride; also from phenol, tert- butyl chloride and
excess alkali in alcohol
Definition
ChEBI: 4-tert-butylphenol is a member of the class of phenols that is phenol substituted with a tert-butyl group at position 4. It has a role as an allergen.
Application
4-tert-Butylphenol may be employed as carbon and energy supplement in the culture medium of Sphingobium fuliginis strains.
4-tert-Butylphenol is suitable reagent used in kinetic study of hydroxylation of 4-tert-butylphenol by mushroom tyrosinase. It may be used in the synthesis of calix[7]arene.
Allgemeine Beschreibung
Crystals or practically white flakes. Has a disinfectant-like odor. May float or sink in water. Insoluble in water.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
Phenols, such as 4-tert-Butylphenol, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.
Hazard
Irritant to eyes and skin.
Brandgefahr
Combustible.
Kontakt-Allergie
Para-tert-butylphenol is used with formaldehyde to
produce the polycondensate p-tert-butylphenol-formaldehyde
resins (PTBPFR). Major occupational sources
are neoprene glues and adhesives in industry, in the
shoemaking and leather industries or in car production.
It is also used as a box preservative in box and furniture
manufacture and in the production of casting molds,
car brake linings, insulated electrical cables, adhesives,
printing inks, and paper laminates. Para-tertbutylphenol
seems to be the sensitizer
Sicherheitsprofil
Poison by
intraperitoneal route. Moderately toxic by
skin contact and ingestion. A skin and
severe eye irritant. Questionable carcinogen
with experimental neoplastigenic data.
Combustible when exposed to heat or
flame; can react with oxidizing materials. To
fight fire, use foam, CO2, dry chemical.
When heated to decomposition it emits
acrid and irritating fumes. See also
PHENOL and other butyl phenols.
mögliche Exposition
Butylphenols may be used as intermediates in manufacturing varnish and lacquer resins; as a
germicidal agent in detergent disinfectants; as a pour point
depressant, in motor-oil additives; de-emulsifier for oil;
soap-antioxidant, plasticizer, fumigant, and insecticide
Versand/Shipping
UN2430 Alkylphenols, solid, n.o.s. (including
C2-C12 homologues), Hazard class: 8; Labels: 8—
Corrosive material
läuterung methode
Crystallise the phenol to constant melting point from pet ether (b 60-80o). It sublimes in vacuo. Also purify it via the benzoate, as for phenol. The salicylate ester [87-18-30] has m 63-64o (from aqueous EtOH, or EtOH). [Beilstein 6 IV 3296.]
Inkompatibilitäten
Vapors may form explosive mixture with
air. These phenol/cresol materials can react with oxidizers;
reaction may be violent. Incompatible with strong reducing
substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat
of the reaction may cause the gas to ignite and explode.
Heat is also generated by the acid-base reaction with bases;
such heating may initiate polymerization of the organic
compound. React with boranes, alkalies, aliphatic amines,
amides, nitric acid, sulfuric acid. Phenols are sulfonated
very readily (for example, by concentrated sulfuric acid at
room temperature). These reactions generate heat. Phenols
are also nitrated very rapidly, even by dilute nitric acid and
can explode when heated. Many phenols form metal salts
that may be detonated by mild shock
4-tert-Butylphenol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
