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Rocuronium bromide Produkt Beschreibung

Rocuronium bromide Struktur
119302-91-9
CAS-Nr.
119302-91-9
Englisch Name:
Rocuronium bromide
Synonyma:
Eslax;Esmeron;Zemuron;Org-9426;Esmeron:Zemuron;ROCURONIUM BROMIDE;ROCURONIUN BROMIDE;ORG 9426 (Bromide);ORG 9426 fandachem;Rocuronium dibromide
CBNumber:
CB2222507
Summenformel:
C32H53BrN2O4
Molgewicht:
609.68
MOL-Datei:
119302-91-9.mol

Rocuronium bromide Eigenschaften

Schmelzpunkt:
162-1640C
alpha 
D20 +18.7° (c = 1.03 in CHCl3)
storage temp. 
Inert atmosphere,2-8°C
Löslichkeit
H2O: soluble100mg/mL, clear, light yellow
Aggregatzustand
neat
Merck 
14,8246
InChIKey
OYTJKRAYGYRUJK-FMCCZJBLSA-M
CAS Datenbank
119302-91-9(CAS DataBase Reference)

Sicherheit

WGK Germany  3
HS Code  2934990002

Rocuronium bromide Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Off-white Solid

Verwenden

A non-depolarizing neuromuscular blocker used in anesthesia to help insert breathing tubes.

Verwenden

Aminosteroid, competitive neuromuscular blocker

Beschreibung

Rocuronium bromide is a short-acting nondepolarizing steroidal neuromuscular blocker introduced in the U.S.A as Zemuron and in the United Kingdom as Esmeron. k is indicated for use as an adjunct to general anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Rocuroniurn bromide has a significantly more rapid onset than other intermediate acting neuromuscular blockers, comparable to succinylcholine but with a very stable cardiovascular profile and has an improved side effect profile. It has been reported that good to excellent intubation conditions were achieved only one minute after a bolus dose of 600μg/kg of rocuronium bromide. It has a short duration of action, therefore, is useful for rapid sequence intubation without unacceptable delays in the spontaneous recovery of neuromuscular function.

Originator

Organon (Netherlands)

Verwenden

Aminosteroid, competitive neuromuscular blocker.

Definition

ChEBI: The organic bromide salt of a 5alpha androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium subs ituents.

Trademarks

Zemuron (Organon).

Biologische Funktion

Rocuronium bromide (Zemuron) is a recently approved amino steroid neuromuscular blocking agent. It has a rapid onset of action (1 minute), but its duration of action is intermediate (55 minutes), about that of vecuronium. On rare occasions, it may release histamine and cause cardiac irregularities. Rapacuronium bromide (Raplon) is the most recent neuromuscular blocking agent approved by the United States Food and Drug Administration (FDA). It is an analogue of vecuronium and is thus categorized as an amino steroid. It has a rapid onset of action (1.5 minutes) and a short to intermediate duration of action (20 minutes).This makes it a suitable alternative to mivacurium or succinylcholine for short procedures. It is eliminated mainly by the liver.Adverse effects are dose dependent; they include tachycardia, hypotension, and bronchospasm. These effects may be related to the ability of the drug to release a small amount of histamine.

Rocuronium bromide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Rocuronium bromide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 374)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Jinan Ande Pharmaceutical Co.,Ltd.
+8613256107535
andepharm@163.com CHINA 220 58
Shandong ruiyue Biological Technology Co.,Ltd.
008615066100122(Lily wechat)
053188581623 513075341@qq.com;1021501167@qq.com;1456922171@qq.com CHINA 52 58
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 sales@capotchem.com China 20012 60
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26782 60
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967
kaia@neputrading.com CHINA 1011 58
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29953 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 19969 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
alice@crovellbio.com China 5942 58

119302-91-9()Verwandte Suche:


  • ROCURONIUM BROMIDE
  • 1-[(2b,3a,5a,16b,17b)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide
  • Esmeron
  • Org-9426
  • Zemuron
  • [3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enyl-2,3,4,5-tetrahydropyrrol-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl] acetate bromide
  • ROCURONIUN BROMIDE
  • Rocuronium Bromide/1-[17B-(acetyloxy)-3a-hydroxy2B-(4-morpholinyl)-5a-androstan-16B-yl]-1-(2-propenyl)pyrrolidinium bromide
  • 1-[17B-(acetyloxy)-3a-hydroxy2B-(4-morpholinyl)-5a -androstan-16B-yl]-1-(2-propenyl)pyrrolidinium bromide
  • 1-[17B-(acetyloxy)-3a-hydroxy-2B-(4-morpholinyl)-
  • 1-[(2,3a,5a,16,17)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide
  • 1-[(2β,3α,5α,16β,17β)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)andrcstan-16-y1]-1-propenylpyrrolidinium bromide
  • Esmeron:Zemuron
  • Eslax
  • Rocuronium Bromide (250 mg)
  • RocuroniuM BroMide IsoMers
  • 1-[(1S,2S,4S,5S,7S,10R,11S,13S,14R,15S)-14-(acetyloxy)-5-hydroxy-2,15-diMethyl-4-(Morpholin-4-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-13-yl]-1-(prop-2-en-1-yl)pyrrolidin-1-iuM
  • 1-[(2β,3α,5α,16β,17β)-17-(Acetyloxy)-3-hydroxy-2-(4-Morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidiniuM BroMide
  • 1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-diMethyl-2-Morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-iuM broMide
  • RocuroniuM BroMideAPI
  • Pyrrolidinium, 1-[(2β,3α,5α,16β,17β)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)-, bromide
  • Rocuronium hydrobromide
  • 1-[17β-(Acetyloxy)-3α-hydroxy-2β-(morpholin-4-yl)-5α-androstan-16β-yl]-1-(prop-2-enyl)pyrrolidinium bromide
  • Rocuronium bromide CRS
  • Rocuronium for peak identification CRS
  • Rocuronium Bromide >
  • ORG 9426 (Bromide)
  • ORG 9426 fandachem
  • Rocuronium dibromide
  • Rocuronium bromide USP/EP/BP
  • Rocuronium Bromide Crude
  • Rocuronium bromide Impurity 47
  • Rocuronium Bromide (ORG 9426 Bromide)
  • 119302-91-9
  • 19302-91-9
  • 119032-86-2
  • BrC32H53N2O4
  • C34H57NO4
  • C32H53BrNO4
  • C32H53N2O4Br
  • C32H53BrN2O4
  • 1
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