Kalium-[2R-(2α,3Z,5α)]-3-(2-hydroxyethyliden)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptan-2-carboxylat
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- CAS-Nr.
- 61177-45-5
- Bezeichnung:
- Kalium-[2R-(2α,3Z,5α)]-3-(2-hydroxyethyliden)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptan-2-carboxylat
- Englisch Name:
- Potassium clavulanate
- Synonyma:
- CLAVULANATE POTASSIUM;Clavulanate;Potassium Clavulanat;potassium calvulanate;Potassium clavulanate USP/EP/BP;MM 1415;Amonate;brl14151k;Clavulanate K;CLAVULANTE POTASSIUM
- CBNumber:
- CB2722502
- Summenformel:
- C8H10KNO5
- Molgewicht:
- 239.27
- MOL-Datei:
- 61177-45-5.mol
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Kalium-[2R-(2α,3Z,5α)]-3-(2-hydroxyethyliden)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptan-2-carboxylat Eigenschaften
- Schmelzpunkt:
- >1600C (dec)
- alpha
- +55～+60°
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- Freely soluble in water, slightly soluble in ethanol (96 per cent), very slightly soluble in acetone.
- InChIKey
- ABVRVIZBZKUTMK-JSYANWSFSA-M
- CAS Datenbank
- 61177-45-5(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H228 |
Entzündbarer Feststoff. |
Entzündbare Feststoffe |
Kategorie 1 |
Achtung
Warnung |
![GHS hazard pictograms]() src="/GHS02.jpg" width="20" height="20" /> |
P210, P240,P241, P280, P370+P378 |
| H252 |
In großen Mengen selbsterhitzungsfähig; kann in Brand geraten. |
Self-heating substances and mixtures |
Category 2 |
Warnung |
|
P235+P410, P280, P407, P413, P420 |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H334 |
Kann bei Einatmen Allergie, asthmaartige Symptome oder Atembeschwerden verursachen. |
Sensibilisierung der Atemwege |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P261, P285, P304+P341, P342+P311,P501 |
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| Sicherheit |
| P210 |
Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P235 |
Kühl halten |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P403+P235 |
An einem gut belüfteten Ort aufbewahren. Kühl halten. |
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Kalium-[2R-(2α,3Z,5α)]-3-(2-hydroxyethyliden)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptan-2-carboxylat Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Clavulanate is a β-lactamase inhibitor that is effective against Ambler class A β-lactamases (IC
50 values range from 12 to 60 nM). While it is not an effective antibiotic by itself, clavulanate is commonly used with other antibiotics that would be inactivated by β-lactamases secreted by bacteria. It is often combined with amoxicillin and other penicillin-based antibiotics.
Chemische Eigenschaften
Pale Yellowish Solid
Verwenden
A -Lactamase inhibitor, typically added to amoxicillin to increase its effectiveness
Definition
ChEBI: A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin
trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases.
Kalium-[2R-(2α,3Z,5α)]-3-(2-hydroxyethyliden)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptan-2-carboxylat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Kalium-[2R-(2α,3Z,5α)]-3-(2-hydroxyethyliden)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptan-2-carboxylat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 276)Lieferanten
61177-45-5(Kalium-[2R-(2α,3Z,5α)]-3-(2-hydroxyethyliden)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptan-2-carboxylat)Verwandte Suche:
- CLAVULANIC ACID POTASSIUM
- CLAVULANIC ACID POTASSIUM SALT
- CLAVULANTE POTASSIUM
- MM 1415
- 4-Oxa-1-azabicyclo3.2.0heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R,3Z,5R)-
- POTASSIUMCLAVULANATE,EP
- 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R,3Z,5R)- (9CI)
- 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, [2R-(2a,3Z,5a)]-
- clavulanate,potassium salt
- CLAVULANIC ACID POTASSIUM SALT (POTASSIUM CLAVULANATE)/AVICEL (1:1)
- Clavulanate K
- Clavulanic acid potassium salt (Potassium Clavulanate)/Avicel (1
- Clavulanate:Cellulose
- Clavulanic acid Potassium salt:Cellulose (1:1)
- Clavulanate PotassiuMAvicel API
- CLAVULANATE POTASSIUM +AVICE
- potassiuM (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
- ClavubactaM potassiuM, BRL 14151
- Clavullinate PotassiuM USP
- Microcrystalline cellulose (1:1)
- potassium clavulanate sterile
- POTASSIUM CLAVULANATE
- potassium (z)-(2r,5r)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
- brl14151k
- monopotassiumsalt,(2r-(2-alpha,3z,5-alpha))-xo
- CLAVULANIC POTASSIUM
- potassium [2R-(2alpha,3Z,5alpha)]-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
- POTASSIUM CLAVULANATE FROM STREPTOMYCES
- 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, potassium salt (1:1), (2R,3Z,5R)-
- Amonate
- Clavaulanate Potassium with
Microcrystalline Cellulose 1:1
- Amoxicillin with Clavulanate Potassium 4:1
- Trihydrate with Clavanate Potassium 4:1
- Potassium Clavulanate Standard
- Sterile Clavulanate Potassium+Amoxicillin
- Clavulanate potassiumQ: What is
Clavulanate potassium Q: What is the CAS Number of
Clavulanate potassium Q: What is the storage condition of
Clavulanate potassium Q: What are the applications of
Clavulanate potassium
- CLAVULANATE POTASSIUM
- Potassium Clavulanat
- Clavulanate
- potassium calvulanate
- Potassium clavulanate USP/EP/BP
- 2,2′-(oxybismethylene)bis[2-(hydroxymethyl)propane-1,3-diol]hexanitrate(dipentaerythritylhexanitrate).
- Amoxicillin and Clavulanate Potassium: 1: 1
- 61177-45-5
- C8H8NO5K
- C8H8KNO5
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