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Glucosamin Produkt Beschreibung

Glucosamine Struktur
3416-24-8
CAS-Nr.
3416-24-8
Bezeichnung:
Glucosamin
Englisch Name:
Glucosamine
Synonyma:
GLUCOSAMINE;aminoglucose;D-GLUCOSAMINE;SYNTHETICGLUCOSAMINE;D-(+)-Glucosamine hy;Propyl N-Acetyl-β2-Amino-2-deoxyglucose;aldehydo-D-glucosamine;GlucosaMine(Feed grade);D-Glucosamine(HCl form)
CBNumber:
CB3414563
Summenformel:
C6H13NO5
Molgewicht:
179.17
MOL-Datei:
3416-24-8.mol

Glucosamin Eigenschaften

Siedepunkt:
311.69°C (rough estimate)
Dichte
1.3767 (rough estimate)
Brechungsindex
1.4240 (estimate)
Schmelzpunkt:
88 °C
pka
pKa 8.04(H2O,t = 15.5,I=0.00,N2)(Approximate)
CAS Datenbank
3416-24-8(CAS DataBase Reference)
EPA chemische Informationen
Glucosamine (3416-24-8)

Sicherheit

Giftige Stoffe Daten 3416-24-8(Hazardous Substances Data)

Glucosamin Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

(β form.) Colorless needles. Mp 110C (decomposes). Very soluble in water; slightly soluble in methanol and ethanol; insoluble in ether and chloroform.

Occurrence

Glucosamine is found in mucopolysaccharides, chitin, and mucoproteins. Glucosamine is a naturally occurring substance; glucosamine sulfate is manufactured synthetically.

Verwenden

Pharmaceutic aid.

Definition

ChEBI: The open-chain form of D-glucosamine.

Trademarks

Adaxil;Antatril;Arthryl;Chitosamine;Corti-anartril;Dona 200-s;Dona compositum;Donna 200;Pona;Terramycin;Terrastatom;Tetracyn;Thiocondramine;Viartril.

Weltgesundheitsorganisation (WHO)

Glucosamine is found in chitin, mucoproteins and mucopolysaccharides. It is used as a pharmaceutical aid. Glucosamine sulfate has been used in the treatment of rheumatic disorders though it is not widely marketed for this purpose.

Veterinary Drugs and Treatments

These compounds may be useful in treating osteoarthritis or other painful conditions in domestic animals, but large, well-designed controlled clinical studies proving efficacy were not located. One study in dogs (McCarthy, O’Donovan et al. 2007) showed some positive effect, but this study was not placebo controlled and compared responses versus carprofen. Another placebo-controlled, blinded study in dogs (Moreau, Dupuis et al. 2003), did not demonstrate statistically significant improvement after 60 days of treatment.
These compounds potentially could be of benefit in cats with FLUTD (feline lower urinary tract disease) because of the presence of glycosaminoglycans as part of the protective layer of the urinary tract. Controlled studies have shown some positive effects in some cats, but overall did not appear to make a significant difference.

läuterung methode

Crystallise the amines from MeOH. The free base has been obtained from the hydrochloride (21.5g, see below) in a mixture of Et3N (15mL) and EtOH (125mL) by shaking for 2days at room temperature, and the solid Et3N.HCl is filtered off and the process repeated with more Et3N (3-4 times) until the D-glucosamine (15g) is free from Cl ions. It has m 88o , [] D20 +100o mutarotating to +47.5o (c 1, H2O). When Et2NH is used as base, the  to  conversion is complete giving D-glucosamine. The pentaacetate is purified by dissolving in CHCl3, treating with charcoal, drying (MgSO4), evaporating the solvent, and adding a little dry Et2O to induce crystallisation. It has m 124-126o, [] D +113o (c 1, CHCl3) after 16hours in a desiccator. [Leaback Biochemical Preparations 10 118 1963.] The N-acetyl derivative, m 203-205o from MeOH/Et2O (dry in vacuum P2O5) has [] D +75o to +41o (c 2, H2O); this derivative can also be purified by dissolving in the minimum volume of H2O to which is added 7-8volumes of EtOH followed by Et2O until turbid and keeping at ~20o to crystallise. Wash the crystals with MeOH then Et2O and dry in vacuo over P2O5. [Horton Biochemical Preparations 11 1 1966.]

Glucosamin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Glucosamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 117)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Henan Xiangtong Chemical Co., Ltd.
86-371-61312303
86-371-86017988 xtchem2019@gmail.com CHINA 286 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22631 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24697 60
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2368 55
City Chemical LLC
2039322489
203.937.8400 sales@citychemical.com United States 98 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23979 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28235 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 14160 58
hdzhl biotechnology co., ltd
86-13032617415
sales@luchibiology.com CHINA 1278 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6372 58

3416-24-8(Glucosamin)Verwandte Suche:


  • 2-Amino-2-deoxyglucose
  • D-Glucose, 2-amino-2-deoxy-
  • SHRIMP-DERIVEDGLUCOSAMINE
  • SYNTHETICGLUCOSAMINE
  • 2-amino-2-deoxy-d-glucos
  • 2-amino-2-deoxy-d-glucose
  • D-GLUCOSAMINE
  • GLUCOSAMINE
  • 2-Amino-2-deoxy-beta-D-glucopyranose
  • 2-Amino-2-deoxy-α-D-glucopyranose
  • 2-Deoxy-2-amino-D-glucopyranose
  • D-(+)-Glucosamine hy
  • GlucosaMine(Feed grade)
  • D-Glucosamine(HCl form)
  • 2-hydroxy-3-(5-(morpholinomethyl)pyridin-2-yl)-1H-indole-5
  • aminoglucose
  • Propyl N-Acetyl-&beta
  • aldehydo-D-glucosamine
  • D-Glucosamine (Free Base)
  • 3416-24-8
  • C6H14O5NCl
  • Inhibitors
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