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Esmolol Produkt Beschreibung

Esmolol Struktur
81147-92-4
CAS-Nr.
81147-92-4
Englisch Name:
Esmolol
Synonyma:
ESMOLOL;asl8052-001;Methyl 3-[4-(2-hydroxy-3-propan-2-ylamino-propoxy)phenyl]propanoate;Methyl 4-[2-hydoxy-3[(1-methylethyl)amino]-propoxy]benzenepropanoate;methyl4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate;4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-benzenepropanoicacimethyle;Methyl 3-[4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]propanoate;3-[4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl]propanoic acid methyl ester;3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester;4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropionic acid methyl ester
CBNumber:
CB6454935
Summenformel:
C16H25NO4
Molgewicht:
295.37
MOL-Datei:
81147-92-4.mol

Esmolol Eigenschaften

Schmelzpunkt:
48-50 °C
Siedepunkt:
430.2±40.0 °C(Predicted)
Dichte
1.026
pka
13.88±0.20(Predicted)
Wasserlöslichkeit
Slightly soluble
Merck 
14,3700
CAS Datenbank
81147-92-4(CAS DataBase Reference)

Sicherheit

RTECS-Nr. DA8345500

Esmolol Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Agricultural chemical.

Hazard

A reproductive hazard.

Clinical Use

Esmolol (Brevibloc) is a short-acting intravenously administered β1-selective adrenoceptor blocking agent. It does not possess membrane-stabilizing activity or sympathomimetic activity.
Esmolol is used in the treatment of supraventricular tachyarrhythmias for rapid control of ventricular rate and reduction of myocardial oxygen consumption. Discontinuation of administration is followed by a rapid reversal of its pharmacological effects because of esmolol’s rapid hydrolysis by plasma esterases.

Nebenwirkungen

The most frequently reported adverse effects are hypotension, nausea, dizziness, headache, and dyspnea.As with many β-blocking drugs, esmolol is contraindicated in patients with overt heart failure and those in cardiogenic shock.

Stoffwechsel

The -blocker esmolol (Brevibloc) is unusual in that it is very rapidly metabolized; its plasma half-life is only 9 minutes. It is subject to hydrolysis by cytosolic esterases in red blood cells to yield methanol and an acid metabolite, the latter having an elimination half-life of about 4 hours. Only 2% of the administered esmolol is excreted unchanged. Because of its rapid onset and short duration of action, esmolol is used by the intravenous route for the control of ventricular arrhythmias in emergencies.

Esmolol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Esmolol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 37)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Henan tianfu chemical co. LTD
0371-55170695
info@hnbon.com CHINA 20537 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47484 58
Mainchem Co., Ltd. +86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32445 55
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TOKYO CHEMICAL INDUSTRY CO., LTD. 03-3668-0489
03-3668-0520 Sales-JP@TCIchemicals.com Japan 28448 80
TCI Europe +32 (0)3 735 07 00
+32 (0)3 735 07 01 sales@tcieurope.eu Europe 27908 75
TCI AMERICA +1-800-423-8616 / +1-503-283-1681
+1-888-520-1075 / +1-503-283-1987 sales@tciamerica.com United States 27728 75
Nanjing Sunlida Biological Technology Co., Ltd. 025-58378339
025-57019371 sales@sunlidabio.com;sales@sunlidabio.com China 3817 55
Wuhan DKY Technology Co.,Ltd. 18007166089 27-81302488-
027-81302088 info@dkybpc.com;2851686510@qq.com China 1986 58
Suzhou Shang Enda Biotechnology Ltd. 0512-66907022 18036087221
0512-66242155 sedswkj@163.com China 103 55

81147-92-4()Verwandte Suche:


  • ESMOLOL
  • 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester
  • 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-benzenepropanoicacimethyle
  • asl8052-001
  • methyl4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate
  • 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester
  • Methyl 3-[4-(2-hydroxy-3-propan-2-ylamino-propoxy)phenyl]propanoate
  • Methyl 4-[2-hydoxy-3[(1-methylethyl)amino]-propoxy]benzenepropanoate
  • 3-[4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl]propanoic acid methyl ester
  • 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropionic acid methyl ester
  • Methyl 3-[4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]propanoate
  • 81147-92-4
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