Natrium-4-propoxycarbonylphenoxid Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White or almost white, hygroscopic, crystalline powder.
Verwenden
Sodium Propylparaben is a preservative. Sodium Propylparaben is also an excipient used in various pharmaceutical formulations.
Vorbereitung Methode
Propylparaben sodium is produced from benzoic acid.
Pharmazeutische Anwendungen
Propylparaben sodium is used as an antimicrobial or antifungal
preservative in oral pharmaceuticals and in many water-based
cosmetics. It is generally used in combination with other paraben
esters.
Kontakt-Allergie
This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid
and an alcohol. They are largely used as biocides in
cosmetics and toiletries, medicaments, or food. They
have synergistic power with other biocides. Parabens
can induce allergic contact dermatitis, mainly in
chronic dermatitis and wounded skin.
Sicherheit(Safety)
Propylparaben sodium is used in oral pharmaceuticals and
cosmetics. The pure form is toxic by the IV route and moderately
toxic by ingestion and the IP route. Propylparaben sodium may
cause asthma, rashes, and hyperactivity.
LD50 (mouse, IP): 0.49 g/kg
LD50 (mouse, IV): 0.18 g/kg
LD50 (mouse, oral): 3.7 g/kg
Lager
Propylparaben sodium is stable under normal conditions. It
decomposes on heating. Store in a tightly closed container.
Inkompatibilitäten
The activity of propylparaben sodium can be adversely affected by
the presence of other excipients or active ingredients, such as
atropine, essential oils, iron, magnesium trisilicate, talc, polysorbate
80 and other nonionic surfactants, sorbitol, weak alkalis, and
strong acids.
Regulatory Status
Included in the FDA Inactive Ingredients Database (oral capsules,
tablets, suspensions). Accepted for use as a food additive in Europe.
Included in nonparenteral medicines (oral capsules, mixtures,
orodispersible tablets, solutions and suspensions; cutaneous emulsions)
licensed in the UK.
Natrium-4-propoxycarbonylphenoxid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
